20 items (Sus scrofa) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Your Input:
	IDO1	Uncharacterized protein. (429 aa)
	DENND1B	DENN domain containing 1B. (766 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (133 aa)
	ANXA1	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa)
	TBX21	Uncharacterized protein. (535 aa)
	STAT6	Signal transducer and activator of transcription. (847 aa)
	ECM1	Extracellular matrix protein 1. (559 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
	IL27RA	Uncharacterized protein. (683 aa)
	RARA	Retinoic acid receptor alpha isoform X1. (462 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
	NDFIP1	Uncharacterized protein. (254 aa)
	CD74	Thyroglobulin type-1 domain-containing protein. (347 aa)
	RSAD2	Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] (362 aa)
	NOD2	Uncharacterized protein. (1013 aa)
	HLX	H2.0 like homeobox. (556 aa)
	BCL6	B-cell lymphoma 6 protein isoform X1. (706 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	CD81	Tetraspanin. (258 aa)
	ARG2	Arginase. (354 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	CD81	ENSSSCP00000005658	ENSSSCP00000073970	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	Tetraspanin.	0.585
ARG2	IDO1	ENSSSCP00000002491	ENSSSCP00000007468	Arginase.	Uncharacterized protein.	0.458
ARG2	IL4	ENSSSCP00000002491	ENSSSCP00000015193	Arginase.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.653
BCL6	GATA3	ENSSSCP00000012581	ENSSSCP00000041348	B-cell lymphoma 6 protein isoform X1.	Trans-acting T-cell-specific transcription factor GATA-3.	0.640
BCL6	IL27RA	ENSSSCP00000012581	ENSSSCP00000029613	B-cell lymphoma 6 protein isoform X1.	Uncharacterized protein.	0.428
BCL6	IL4	ENSSSCP00000012581	ENSSSCP00000015193	B-cell lymphoma 6 protein isoform X1.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.773
BCL6	STAT6	ENSSSCP00000012581	ENSSSCP00000019659	B-cell lymphoma 6 protein isoform X1.	Signal transducer and activator of transcription.	0.401
BCL6	TBX21	ENSSSCP00000012581	ENSSSCP00000018565	B-cell lymphoma 6 protein isoform X1.	Uncharacterized protein.	0.703
CD81	ANXA1	ENSSSCP00000073970	ENSSSCP00000005658	Tetraspanin.	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	0.585
GATA3	BCL6	ENSSSCP00000041348	ENSSSCP00000012581	Trans-acting T-cell-specific transcription factor GATA-3.	B-cell lymphoma 6 protein isoform X1.	0.640
GATA3	IL4	ENSSSCP00000041348	ENSSSCP00000015193	Trans-acting T-cell-specific transcription factor GATA-3.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.806
GATA3	STAT6	ENSSSCP00000041348	ENSSSCP00000019659	Trans-acting T-cell-specific transcription factor GATA-3.	Signal transducer and activator of transcription.	0.699
GATA3	TBX21	ENSSSCP00000041348	ENSSSCP00000018565	Trans-acting T-cell-specific transcription factor GATA-3.	Uncharacterized protein.	0.992
IDO1	ARG2	ENSSSCP00000007468	ENSSSCP00000002491	Uncharacterized protein.	Arginase.	0.458
IDO1	IL4	ENSSSCP00000007468	ENSSSCP00000015193	Uncharacterized protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.601
IL27RA	BCL6	ENSSSCP00000029613	ENSSSCP00000012581	Uncharacterized protein.	B-cell lymphoma 6 protein isoform X1.	0.428
IL27RA	IL4	ENSSSCP00000029613	ENSSSCP00000015193	Uncharacterized protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.708
IL4	ARG2	ENSSSCP00000015193	ENSSSCP00000002491	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	Arginase.	0.653
IL4	BCL6	ENSSSCP00000015193	ENSSSCP00000012581	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	B-cell lymphoma 6 protein isoform X1.	0.773
IL4	GATA3	ENSSSCP00000015193	ENSSSCP00000041348	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	Trans-acting T-cell-specific transcription factor GATA-3.	0.806