58 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GDF11	Growth/differentiation factor 11 preproprotein. (404 aa)
	NRL	Neural retina leucine zipper. (237 aa)
	RPGRIP1	RPGR interacting protein 1. (939 aa)
	CRB2	Crumbs cell polarity complex component 2. (1283 aa)
	CALB1	Calbindin 1. (261 aa)
	HIPK1	Homeodomain-interacting protein kinase 1 isoform 1. (1210 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	BARHL2	BarH like homeobox 2. (384 aa)
	FOXN4	Fork-head domain-containing protein. (517 aa)
	NF2	Neurofibromin 2. (586 aa)
	PDE6C	Phosphodiesterase. (859 aa)
	CRB1	Crumbs cell polarity complex component 1. (1464 aa)
	ACTL6A	Actin-like protein 6A isoform X1; Belongs to the actin family. (429 aa)
	USH1C	USH1 protein network component harmonin. (858 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
	STAT3	Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa)
	FJX1	Four-jointed box kinase 1. (437 aa)
	HCN1	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (885 aa)
	GPM6A	Glycoprotein M6A. (278 aa)
	VSX1	Visual system homeobox 1. (364 aa)
	ATOH7	Atonal bHLH transcription factor 7. (155 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1208 aa)
	PTF1A	Pancreas associated transcription factor 1a. (328 aa)
	IGFN1	Uncharacterized protein. (1253 aa)
	RS1	Retinoschisin 1. (228 aa)
	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1647 aa)
	LHX1	LIM homeobox 1. (436 aa)
	RPGRIP1L	Protein fantom isoform X1. (1270 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (548 aa)
	SOX8	SRY-box transcription factor 8. (460 aa)
	RDH13	Retinol dehydrogenase 13 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
	LOC110258874	Fork-head domain-containing protein. (493 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1507 aa)
	TFAP2B	Transcription factor AP-2 beta. (469 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	NEUROD4	Neurogenic differentiation factor. (331 aa)
	MEGF11	Multiple EGF like domains 11. (1140 aa)
	MYPN	Myopalladin isoform a. (1320 aa)
	HES1	Uncharacterized protein. (280 aa)
	NOTCH1	Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
	PROM1	Prominin 1. (838 aa)
	THY1	Thy-1 cell surface antigen. (165 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	TSPAN12	Tetraspanin. (305 aa)
	TTC8	Tetratricopeptide repeat domain 8. (587 aa)
	AHI1	Abelson helper integration site 1. (1114 aa)
	TTN	Uncharacterized protein. (563 aa)
	THRB	Thyroid hormone receptor beta isoform X2. (476 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (744 aa)
	CABP4	Calcium binding protein 4. (311 aa)
	BBS4	Uncharacterized protein. (826 aa)
	CNTF	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy (By similarity). (619 aa)
	RP1	RP1 axonemal microtubule associated. (2142 aa)
	RORB	RAR related orphan receptor B. (548 aa)
	ZHX2	Zinc fingers and homeoboxes 2. (827 aa)
	SDK1	Sidekick cell adhesion molecule 1. (2141 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL6A	SMARCA4	ENSSSCP00000012532	ENSSSCP00000031107	Actin-like protein 6A isoform X1; Belongs to the actin family.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.	0.993
ACTL6A	SMARCD3	ENSSSCP00000012532	ENSSSCP00000034915	Actin-like protein 6A isoform X1; Belongs to the actin family.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3.	0.957
AHI1	RPGRIP1	ENSSSCP00000058055	ENSSSCP00000002328	Abelson helper integration site 1.	RPGR interacting protein 1.	0.527
AHI1	RPGRIP1L	ENSSSCP00000058055	ENSSSCP00000032496	Abelson helper integration site 1.	Protein fantom isoform X1.	0.823
ATOH7	FOXN4	ENSSSCP00000023438	ENSSSCP00000010603	Atonal bHLH transcription factor 7.	Fork-head domain-containing protein.	0.729
ATOH7	GDF11	ENSSSCP00000023438	ENSSSCP00000000380	Atonal bHLH transcription factor 7.	Growth/differentiation factor 11 preproprotein.	0.495
ATOH7	GNAT2	ENSSSCP00000023438	ENSSSCP00000007278	Atonal bHLH transcription factor 7.	G protein subunit alpha transducin 2.	0.553
ATOH7	LOC110258874	ENSSSCP00000023438	ENSSSCP00000036845	Atonal bHLH transcription factor 7.	Fork-head domain-containing protein.	0.527
ATOH7	PTF1A	ENSSSCP00000023438	ENSSSCP00000025304	Atonal bHLH transcription factor 7.	Pancreas associated transcription factor 1a.	0.537
ATOH7	RORB	ENSSSCP00000023438	ENSSSCP00000070829	Atonal bHLH transcription factor 7.	RAR related orphan receptor B.	0.621
ATOH7	VSX1	ENSSSCP00000023438	ENSSSCP00000023121	Atonal bHLH transcription factor 7.	Visual system homeobox 1.	0.711
BARHL2	FOXN4	ENSSSCP00000007371	ENSSSCP00000010603	BarH like homeobox 2.	Fork-head domain-containing protein.	0.608
BARHL2	LOC110258874	ENSSSCP00000007371	ENSSSCP00000036845	BarH like homeobox 2.	Fork-head domain-containing protein.	0.608
BARHL2	PTF1A	ENSSSCP00000007371	ENSSSCP00000025304	BarH like homeobox 2.	Pancreas associated transcription factor 1a.	0.809
BBS4	RPGRIP1L	ENSSSCP00000066147	ENSSSCP00000032496	Uncharacterized protein.	Protein fantom isoform X1.	0.503
BBS4	TTC8	ENSSSCP00000066147	ENSSSCP00000055383	Uncharacterized protein.	Tetratricopeptide repeat domain 8.	0.997
CABP4	ROM1	ENSSSCP00000065271	ENSSSCP00000051122	Calcium binding protein 4.	Retinal outer segment membrane protein 1.	0.400
CABP4	RPGRIP1	ENSSSCP00000065271	ENSSSCP00000002328	Calcium binding protein 4.	RPGR interacting protein 1.	0.558
CALB1	SOX9	ENSSSCP00000006534	ENSSSCP00000018278	Calbindin 1.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.493
CRB1	CRB2	ENSSSCP00000011618	ENSSSCP00000005978	Crumbs cell polarity complex component 1.	Crumbs cell polarity complex component 2.	0.914