28 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	CENPP	Centromere protein P. (286 aa)
	KAT6B	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2065 aa)
	HAT1	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (418 aa)
	KAT2A	Lysine acetyltransferase 2A. (857 aa)
	EP300	E1A binding protein p300. (2420 aa)
	MCM3AP	Minichromosome maintenance complex component 3 associated protein. (1860 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa)
	TAF1	Transcription initiation factor TFIID subunit. (2001 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (831 aa)
	BRCA2	Tower domain-containing protein. (1163 aa)
	GTF3C4	General transcription factor 3C polypeptide 4. (679 aa)
	CLOCK	Clock circadian regulator. (857 aa)
	TAF9	Transcription initiation factor TFIID subunit 9. (265 aa)
	USP22	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (522 aa)
	KAT8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (461 aa)
	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit. (239 aa)
	KAT7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa)
	KAT6A	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (829 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (576 aa)
	METTL8	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (426 aa)
	NCOA1	Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...] (1441 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	A0A287B8J8_PIG	Uncharacterized protein. (617 aa)
	NAA60	N(alpha)-acetyltransferase 60, NatF catalytic subunit. (327 aa)
	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit. (168 aa)
	GTF2B	General transcription factor IIB. (337 aa)
	NCOA3	Uncharacterized protein. (1296 aa)
	CREBBP	CREB-binding protein isoform a. (2440 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A287B8J8_PIG	BRCA2	ENSSSCP00000052851	ENSSSCP00000028073	Uncharacterized protein.	Tower domain-containing protein.	0.900
ATF2	CREBBP	ENSSSCP00000052628	ENSSSCP00000008490	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	CREB-binding protein isoform a.	0.970
ATF2	EP300	ENSSSCP00000052628	ENSSSCP00000020812	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	E1A binding protein p300.	0.905
ATF2	HAT1	ENSSSCP00000052628	ENSSSCP00000016904	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	0.497
ATF2	KAT5	ENSSSCP00000052628	ENSSSCP00000065734	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.414
ATF2	KAT8	ENSSSCP00000052628	ENSSSCP00000060374	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.406
BRCA2	A0A287B8J8_PIG	ENSSSCP00000028073	ENSSSCP00000052851	Tower domain-containing protein.	Uncharacterized protein.	0.900
CENPP	GTF2B	ENSSSCP00000008619	ENSSSCP00000007384	Centromere protein P.	General transcription factor IIB.	0.438
CLOCK	CREBBP	ENSSSCP00000039247	ENSSSCP00000008490	Clock circadian regulator.	CREB-binding protein isoform a.	0.607
CLOCK	EP300	ENSSSCP00000039247	ENSSSCP00000020812	Clock circadian regulator.	E1A binding protein p300.	0.464
CREBBP	ATF2	ENSSSCP00000008490	ENSSSCP00000052628	CREB-binding protein isoform a.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.970
CREBBP	CLOCK	ENSSSCP00000008490	ENSSSCP00000039247	CREB-binding protein isoform a.	Clock circadian regulator.	0.607
CREBBP	EP300	ENSSSCP00000008490	ENSSSCP00000020812	CREB-binding protein isoform a.	E1A binding protein p300.	0.997
CREBBP	GTF2B	ENSSSCP00000008490	ENSSSCP00000007384	CREB-binding protein isoform a.	General transcription factor IIB.	0.489
CREBBP	KAT2A	ENSSSCP00000008490	ENSSSCP00000018451	CREB-binding protein isoform a.	Lysine acetyltransferase 2A.	0.952
CREBBP	KAT2B	ENSSSCP00000008490	ENSSSCP00000026852	CREB-binding protein isoform a.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.973
CREBBP	KAT5	ENSSSCP00000008490	ENSSSCP00000065734	CREB-binding protein isoform a.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.422
CREBBP	KAT6A	ENSSSCP00000008490	ENSSSCP00000056682	CREB-binding protein isoform a.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.561
CREBBP	NCOA1	ENSSSCP00000008490	ENSSSCP00000048096	CREB-binding protein isoform a.	Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...]	0.986
CREBBP	NCOA3	ENSSSCP00000008490	ENSSSCP00000007946	CREB-binding protein isoform a.	Uncharacterized protein.	0.956