STRINGSTRING
SCD5 SCD5 TET2 TET2 FBXL5 FBXL5 XDH XDH CYP26B1 CYP26B1 PHF2 PHF2 LOC100737768 LOC100737768 HBZ HBZ CYP2W1 CYP2W1 CYP24A1 CYP24A1 PTGIS PTGIS CYP7B1 CYP7B1 F1S3X0_PIG F1S3X0_PIG CYP4A24 CYP4A24 LOC100522145 LOC100522145 FTL FTL ETHE1 ETHE1 CYP2B22 CYP2B22 CYP2F1 CYP2F1 CYP2A19 CYP2A19 FA2H FA2H CYP46A1 CYP46A1 EGLN3 EGLN3 CYP1A1 CYP1A1 CYP1A2 CYP1A2 P3H3 P3H3 TPH2 TPH2 CYP2D25 CYP2D25 PIGS PIGS TF-2 TF-2 SCD SCD LOC102167481 LOC102167481 A0A5G2RE08_PIG A0A5G2RE08_PIG ISCA2 ISCA2 ABCE1 ABCE1 A0A5G2QZD3_PIG A0A5G2QZD3_PIG NFU1 NFU1 CYP2E1 CYP2E1 EGLN2-2 EGLN2-2 FXN FXN P3H4 P3H4 PLOD1 PLOD1 AOX4 AOX4 A0A5G2R083_PIG A0A5G2R083_PIG EGLN2 EGLN2 MIOX MIOX PPEF2 PPEF2 HBM HBM PLOD3 PLOD3 MIOX-2 MIOX-2 CYP21A2 CYP21A2 CYP4A21 CYP4A21 PAH PAH JMJD6 JMJD6 SAAL1 SAAL1 ACO1 ACO1 CH25H CH25H CYP39A1 CYP39A1 CYP2C36 CYP2C36 CYP4F3 CYP4F3 CYP1B1 CYP1B1 LCN2 LCN2 A0A287B9Z5_PIG A0A287B9Z5_PIG P4HA2 P4HA2 ADO ADO HIF1AN HIF1AN CYP4F2 CYP4F2 CYP4V2 CYP4V2 CCNDBP1 CCNDBP1 TH TH LYRM4 LYRM4 FTO FTO CYP19A1 CYP19A1 A0A287ARF8_PIG A0A287ARF8_PIG TTI2 TTI2 FAXDC2 FAXDC2 CRTAP CRTAP FTH1 FTH1 DNAJC24 DNAJC24 A0A287AK55_PIG A0A287AK55_PIG CYP4B1 CYP4B1 LOC110260194 LOC110260194 METTL26 METTL26 A0A287AFR3_PIG A0A287AFR3_PIG DOHH DOHH A0A287AF21_PIG A0A287AF21_PIG OGFOD1 OGFOD1 CYP51A1 CYP51A1 CYP2R1 CYP2R1 CYP8B1 CYP8B1 CYP2S1 CYP2S1 A0A287A6V0_PIG A0A287A6V0_PIG A0A287A5K8_PIG A0A287A5K8_PIG RIOX1 RIOX1 CYP2U1 CYP2U1 A0A286ZXL3_PIG A0A286ZXL3_PIG LOC110256857 LOC110256857 MSMO1 MSMO1 A0A286ZW25_PIG A0A286ZW25_PIG P4HA1 P4HA1 LOC110255328 LOC110255328 A0A286ZRK1_PIG A0A286ZRK1_PIG CYP7A1 CYP7A1 A0A286ZQC2_PIG A0A286ZQC2_PIG OGFOD3 OGFOD3 HAAO HAAO RIOX2 RIOX2 ALOX5 ALOX5 CYP2J34 CYP2J34 ALOX15 ALOX15 HBQ1 HBQ1 CCDC160 CCDC160 SC5D SC5D LTF LTF ISCU ISCU PPEF1 PPEF1 LOC102162930 LOC102162930 I3LP88_PIG I3LP88_PIG P4HA3 P4HA3 ALKBH1 ALKBH1 CYP4F22 CYP4F22 EIPR1 EIPR1 CYP11A1 CYP11A1 CYP27B1 CYP27B1 CYP4F8 CYP4F8 CYP3A22 CYP3A22 ADI1 ADI1 AOX1 AOX1 CYP27A1 CYP27A1 ALKBH8 ALKBH8 LOC100627093 LOC100627093 P3H1 P3H1 LOC100737508 LOC100737508 ALOXE3 ALOXE3 ALOX12B ALOX12B ALOX15B ALOX15B CYGB CYGB F1SJA8_PIG F1SJA8_PIG TBXAS1 TBXAS1 KDM7A KDM7A AOX2 AOX2 TYW5 TYW5 FTMT FTMT CDO1 CDO1 ACP5 ACP5 BBOX1 BBOX1 TMLHE TMLHE HEPH HEPH PHF8 PHF8 F1RXT0_PIG F1RXT0_PIG FTHL17 FTHL17 MELTF MELTF P3H2 P3H2 PLOD2 PLOD2 P4HTM P4HTM CYP17A1 CYP17A1 CYP2C33 CYP2C33 CYP26A1 CYP26A1 CYP26C1 CYP26C1 KDM3A KDM3A TET1 TET1 EGLN1 EGLN1 ALKBH2 ALKBH2 OGFOD2 OGFOD2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (332 aa)
TET2Tet methylcytosine dioxygenase 2. (2019 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
XDHXanthine dehydrogenase/oxidase. (1336 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
PHF2PHD finger protein 2. (1107 aa)
LOC100737768Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues. (142 aa)
HBZHemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin; Belongs to the globin family. (142 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (469 aa)
CYP24A125-hydroxyvitamin D3-24-hydroxylase; Belongs to the cytochrome P450 family. (514 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (503 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa)
F1S3X0_PIGUncharacterized protein. (285 aa)
CYP4A24Cytochrome P450 4A24; Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Has no activity toward taurochenodeoxycholic acid; Belongs to the cytochrome P450 family. (482 aa)
LOC100522145Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
FTLFerritin light chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity); Belongs to the ferritin family. (206 aa)
ETHE1ETHE1 persulfide dioxygenase. (257 aa)
CYP2B22Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (492 aa)
CYP2A19Cytochorme P450 2A19; Belongs to the cytochrome P450 family. (494 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (371 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (501 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (538 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
P3H3Prolyl 3-hydroxylase 3. (727 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
CYP2D25Vitamin D(3) 25-hydroxylase; Catalyzes the first step in the metabolic activation of vitamin D(3) into 1-alpha,25-dihydroxyvitamin D(3), its active, hormonal form. (500 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (622 aa)
TF-2Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (702 aa)
SCDAcyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid ox [...] (425 aa)
LOC102167481Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
A0A5G2RE08_PIGNifU_N domain-containing protein. (190 aa)
ISCA2Iron-sulfur cluster assembly 2. (208 aa)
ABCE1ATP binding cassette subfamily E member 1. (589 aa)
A0A5G2QZD3_PIGUncharacterized protein. (153 aa)
NFU1NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 2. (253 aa)
CYP2E1Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (499 aa)
EGLN2-2Fe2OG dioxygenase domain-containing protein. (125 aa)
FXNFrataxin. (264 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (455 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (726 aa)
AOX4Uncharacterized protein. (1335 aa)
A0A5G2R083_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (177 aa)
EGLN2Uncharacterized protein. (257 aa)
MIOXInositol oxygenase. (320 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (751 aa)
HBMHemoglobin subunit mu; Belongs to the globin family. (192 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa)
MIOX-2Inositol oxygenase. (293 aa)
CYP21A2Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. (526 aa)
CYP4A21Cytochrome P450 4A24; Belongs to the cytochrome P450 family. (529 aa)
PAHPhenylalanine hydroxylase. (450 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa)
SAAL1Serum amyloid A like 1. (490 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
CH25HCholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. Plays a key role in cell positioning and movement in lymphoid tissues: 25- hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25- dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory eleme [...] (311 aa)
CYP39A1Uncharacterized protein; Belongs to the cytochrome P450 family. (461 aa)
CYP2C36Cytochrome P450 2C42; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (843 aa)
CYP4F3Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (524 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
LCN2Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (314 aa)
A0A287B9Z5_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (141 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha 2. (555 aa)
ADO2-aminoethanethiol (Cysteamine) dioxygenase. (270 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (361 aa)
CYP4F2Phylloquinone omega-hydroxylase CYP4F2; Belongs to the cytochrome P450 family. (524 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
CCNDBP1Cyclin-D1-binding protein 1. (357 aa)
THTyrosine hydroxylase. (596 aa)
LYRM4Uncharacterized protein; Belongs to the complex I LYR family. (301 aa)
FTOFTO_NTD domain-containing protein. (509 aa)
CYP19A1Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. (551 aa)
A0A287ARF8_PIGUncharacterized protein. (161 aa)
TTI2TELO2 interacting protein 2. (507 aa)
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (338 aa)
CRTAPCartilage-associated protein. (401 aa)
FTH1Ferritin heavy chain, N-terminally processed; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). (181 aa)
DNAJC24DnaJ heat shock protein family (Hsp40) member C24. (187 aa)
A0A287AK55_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (133 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (459 aa)
LOC110260194Cytochrome P450 11B1, mitochondrial; A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) [...] (503 aa)
METTL26Methyltransferase like 26. (204 aa)
A0A287AFR3_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (75 aa)
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (305 aa)
A0A287AF21_PIGFerritin domain-containing protein. (154 aa)
OGFOD12-oxoglutarate and iron dependent oxygenase domain containing 1. (560 aa)
CYP51A1Lanosterol 14-alpha demethylase; A cytochrome P450 monooxygenase involved in sterol biosynthesis. Catalyzes 14-alpha demethylation of lanosterol and 24,25- dihydrolanosterol likely through sequential oxidative conversion of 14- alpha methyl group to hydroxymethyl, then to carboxylaldehyde, followed by the formation of the delta 14,15 double bond in the sterol core and concomitant release of formic acid. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P45 [...] (503 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (500 aa)
CYP8B15-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Involved in bile acid synthesis and is responsible for the conversion of 5 beta-cholestane-3-alpha,7-alpha-diol into 5 beta- cholestane-3-alpha,7-alpha,12-alpha triol. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. The enzyme can also hydroxylate the substrate at the 25 and 26 position, but to a lesser extent. (501 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (650 aa)
A0A287A6V0_PIGUncharacterized protein. (155 aa)
A0A287A5K8_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (74 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (667 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa)
A0A286ZXL3_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (72 aa)
LOC110256857Uncharacterized protein. (162 aa)
MSMO1Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family. (293 aa)
A0A286ZW25_PIGUncharacterized protein. (80 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha-1 isoform 1. (534 aa)
LOC110255328Uncharacterized protein; Belongs to the cytochrome P450 family. (507 aa)
A0A286ZRK1_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
CYP7A1Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] (554 aa)
A0A286ZQC2_PIGUncharacterized protein. (502 aa)
OGFOD3P4Hc domain-containing protein. (470 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (464 aa)
ALOX5Arachidonate 5-lipoxygenase. (638 aa)
CYP2J34Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa)
ALOX15Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (786 aa)
HBQ1Hemoglobin subunit theta-1; Belongs to the globin family. (142 aa)
CCDC160Coiled-coil domain-containing protein 160 isoform X1. (324 aa)
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (336 aa)
LTFLactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa)
ISCUIron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (196 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (652 aa)
LOC102162930Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
I3LP88_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha-3 isoform 1. (544 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (425 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the sec [...] (520 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (678 aa)
CYP3A22Cytochrome P450 3A29; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (667 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
AOX1Uncharacterized protein. (1338 aa)
CYP27A1Uncharacterized protein; Belongs to the cytochrome P450 family. (581 aa)
ALKBH8AlkB homolog 8, tRNA methyltransferase. (614 aa)
LOC100627093Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
P3H1Prolyl 3-hydroxylase 1 isoform 1. (698 aa)
LOC100737508Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
ALOXE3Arachidonate lipoxygenase 3. (710 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (698 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (718 aa)
CYGBGLOBIN domain-containing protein; Belongs to the globin family. (410 aa)
F1SJA8_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (221 aa)
TBXAS1Thromboxane-A synthase; Belongs to the cytochrome P450 family. (535 aa)
KDM7ALysine-specific demethylase 7A. (942 aa)
AOX2Uncharacterized protein. (1345 aa)
TYW5tRNA wybutosine-synthesizing protein 5. (315 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (242 aa)
CDO1Cysteine dioxygenase. (200 aa)
ACP5Tartrate-resistant acid phosphatase type 5; Uteroferrin is a phosphoprotein phosphatase, synthesized in response to progesterone. It appears to function in transplacental transport of iron in pig. (373 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (387 aa)
TMLHETrimethyllysine dioxygenase, mitochondrial isoform 1. (421 aa)
HEPHHephaestin; Belongs to the multicopper oxidase family. (1210 aa)
PHF8PHD finger protein 8. (1060 aa)
F1RXT0_PIGFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (177 aa)
FTHL17Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (737 aa)
P3H2Prolyl 3-hydroxylase 2 isoform a. (706 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (760 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (496 aa)
CYP17A1Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (509 aa)
CYP2C33Cytochrome P450 2C8 isoform a; Belongs to the cytochrome P450 family. (494 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
KDM3ALysine demethylase 3A. (1323 aa)
TET1CXXC-type domain-containing protein. (2149 aa)
EGLN1Uncharacterized protein. (427 aa)
ALKBH2AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (260 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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