STRINGSTRING
PPP1R3D PPP1R3D GYS1 GYS1 GSK3A GSK3A G6PC G6PC SLC37A4 SLC37A4 PPP1CC PPP1CC PPP1R3B PPP1R3B ACADM ACADM GSK3B GSK3B GBE1 GBE1 PYGB PYGB GYG2 GYG2 STBD1 STBD1 PPP1CB PPP1CB AGL AGL GYS2 GYS2 PHKA2 PHKA2 PYGM PYGM PYGL PYGL PHKB PHKB EPM2AIP1 EPM2AIP1 NR1D1 NR1D1 GYG1 GYG1 STK40 STK40 PPP1CA PPP1CA UGP2 UGP2 IL6ST IL6ST RB1CC1 RB1CC1 LEPR LEPR GAA GAA PRKAG2 PRKAG2 PRKAG3 PRKAG3 PCDH12 PCDH12 PHKA1 PHKA1 PPP1R3C PPP1R3C PGM2 PGM2 PHKG2 PHKG2 PHKG1 PHKG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R3DProtein phosphatase 1 regulatory subunit. (299 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (744 aa)
GSK3AProtein kinase domain-containing protein. (566 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (369 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (339 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). (454 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (414 aa)
GBE11,4-alpha-glucan branching enzyme 1. (702 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
GYG2Glycogenin 2. (488 aa)
STBD1CBM20 domain-containing protein. (508 aa)
PPP1CBSerine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] (389 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1541 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (699 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1237 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1369 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1090 aa)
EPM2AIP1EPM2A interacting protein 1. (608 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1 isoform X2. (616 aa)
GYG1Glycogenin 1. (333 aa)
STK40Serine/threonine-protein kinase 40 isoform 2. (435 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase; Plays a central role as a glucosyl donor in cellular metabolic pathways; Belongs to the UDPGP type 1 family. (517 aa)
IL6STInterleukin 6 signal transducer. (938 aa)
RB1CC1RB1 inducible coiled-coil 1. (1608 aa)
LEPRLeptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] (1165 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (937 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (619 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] (499 aa)
PCDH12Protocadherin 12. (1200 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1227 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
PGM2Phosphoglucomutase 2. (624 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
PHKG1Phosphorylase kinase gamma 1; Belongs to the protein kinase superfamily. (388 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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