STRINGSTRING
STX18 STX18 ZFYVE27 ZFYVE27 LNPK LNPK RETREG3 RETREG3 VAPB VAPB TMEM170A TMEM170A GET4 GET4 SEC61A1 SEC61A1 TRAM1 TRAM1 ATL2 ATL2 REEP3 REEP3 RNF112 RNF112 REEP4 REEP4 GET3 GET3 TMCC1 TMCC1 PEX5 PEX5 PCNX1 PCNX1 CAMLG CAMLG TRAM2 TRAM2 PCNX4 PCNX4 ATL3 ATL3 TMEM33 TMEM33 SEC16B SEC16B TMEM38B TMEM38B SEC16A SEC16A GET1 GET1 RETREG1 RETREG1 EMC4 EMC4 LOC100627175 LOC100627175 UBL4B UBL4B LMAN2L LMAN2L CERT1 CERT1 TOR1AIP2 TOR1AIP2 TEX28 TEX28 C6H16orf74 C6H16orf74 CCDC47 CCDC47 ESYT3 ESYT3 POLR2M POLR2M BNIP1 BNIP1 CAV2 CAV2 RETREG2 RETREG2 EMC1 EMC1 MIA3 MIA3 CACNA1S CACNA1S MOSPD3 MOSPD3 LPCAT3 LPCAT3 EMC8 EMC8 REEP5 REEP5 SGTA SGTA SEC31A SEC31A EMC2 EMC2 REEP1 REEP1 ESYT1 ESYT1 EMC10 EMC10 SEC31B SEC31B SPTSSB SPTSSB WDR83OS WDR83OS REEP2 REEP2 LMAN2 LMAN2 UMOD UMOD PCNX2 PCNX2 SHTN1 SHTN1 EMC3 EMC3 CXorf56 CXorf56 PCNX3 PCNX3 LRRK2 LRRK2 BAG6 BAG6 LMAN1L LMAN1L RTN3 RTN3 GRAMD2A GRAMD2A EMC9 EMC9 LMAN1 LMAN1 ATL1 ATL1 VCPIP1 VCPIP1 CASQ1 CASQ1 RTN4 RTN4 TMEM38A TMEM38A ESYT2 ESYT2 A0A287BDP1_PIG A0A287BDP1_PIG EMC7 EMC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STX18Syntaxin 18. (341 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (404 aa)
LNPKLunapark, ER junction formation factor. (429 aa)
RETREG3Reticulophagy regulator family member 3. (466 aa)
VAPBVesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. (309 aa)
TMEM170AUncharacterized protein. (144 aa)
GET4Uncharacterized protein. (668 aa)
SEC61A1SEC61 translocon alpha 1 subunit. (481 aa)
TRAM1TLC domain-containing protein. (409 aa)
ATL2Atlastin GTPase 2. (584 aa)
REEP3Receptor expression-enhancing protein. (253 aa)
RNF112Ring finger protein 112. (628 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
GET3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (347 aa)
TMCC1Uncharacterized protein. (657 aa)
PEX5Peroxisomal biogenesis factor 5. (660 aa)
PCNX1Pecanex 1. (2341 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (300 aa)
TRAM2Translocation associated membrane protein 2. (392 aa)
PCNX4Pecanex 4. (1233 aa)
ATL3Atlastin GTPase 3. (553 aa)
TMEM33Transmembrane protein 33. (326 aa)
SEC16BProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1021 aa)
TMEM38BTrimeric intracellular cation channel type B. (290 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2318 aa)
GET1Guided entry of tail-anchored proteins factor 1. (174 aa)
RETREG1Reticulophagy regulator 1. (565 aa)
EMC4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (183 aa)
LOC100627175GRAM domain-containing protein 2A isoform X1. (365 aa)
UBL4BUbiquitin-like domain-containing protein. (62 aa)
LMAN2LLectin, mannose binding 2 like. (388 aa)
CERT1Ceramide transporter 1. (562 aa)
TOR1AIP2Torsin 1A interacting protein 2. (531 aa)
TEX28Testis expressed 28. (408 aa)
C6H16orf74Uncharacterized protein. (74 aa)
CCDC47Coiled-coil domain-containing protein 47. (483 aa)
ESYT3Extended synaptotagmin 3. (889 aa)
POLR2MRNA polymerase II subunit M. (369 aa)
BNIP1BCL2 interacting protein 1. (228 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa)
RETREG2Reticulophagy regulator family member 2. (542 aa)
EMC1ER membrane protein complex subunit 1. (1075 aa)
MIA3MIA SH3 domain ER export factor 3. (1996 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
MOSPD3MSP domain-containing protein. (308 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
EMC8Uncharacterized protein. (284 aa)
REEP5Receptor expression-enhancing protein. (209 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (394 aa)
SEC31ASEC31 homolog A, COPII coat complex component. (1251 aa)
EMC2ER membrane protein complex subunit 2. (326 aa)
REEP1Receptor expression-enhancing protein. (359 aa)
ESYT1Extended synaptotagmin 1. (1109 aa)
EMC10ER membrane protein complex subunit 10. (273 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1210 aa)
SPTSSBSerine palmitoyltransferase small subunit B. (110 aa)
WDR83OSProtein Asterix; Belongs to the Asterix family. (110 aa)
REEP2Receptor expression-enhancing protein. (275 aa)
LMAN2Lectin, mannose binding 2. (359 aa)
UMODUromodulin. (642 aa)
PCNX2Uncharacterized protein. (414 aa)
SHTN1Shootin 1. (631 aa)
EMC3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
CXorf56Chromosome X open reading frame 56. (222 aa)
PCNX3Pecanex-like protein 3. (2031 aa)
LRRK2Uncharacterized protein. (2501 aa)
BAG6Large proline-rich protein BAG6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1163 aa)
LMAN1LLectin, mannose binding 1 like. (504 aa)
RTN3Reticulon. (255 aa)
GRAMD2AGRAM domain-containing protein. (314 aa)
EMC9ER membrane protein complex subunit 9 isoform X1. (206 aa)
LMAN1Lectin, mannose binding 1. (518 aa)
ATL1Atlastin GTPase 1. (558 aa)
VCPIP1Valosin containing protein interacting protein 1. (1223 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa)
RTN4Reticulon. (1199 aa)
TMEM38ATrimeric intracellular cation channel type A. (299 aa)
ESYT2Extended synaptotagmin 2. (863 aa)
A0A287BDP1_PIGUncharacterized protein. (48 aa)
EMC7DUF2012 domain-containing protein. (250 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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