STRINGSTRING
BCL2L11 BCL2L11 FGB FGB HPSE HPSE THSD1 THSD1 NID1 NID1 VWA2 VWA2 ITGA8 ITGA8 ITGA9 ITGA9 BCL6 BCL6 COL5A3 COL5A3 ADAM9 ADAM9 HOXD3 HOXD3 ZYX ZYX ITGA2 ITGA2 CDK5 CDK5 ILK ILK VTN VTN FGG FGG TAOK2 TAOK2 RHOD RHOD ACTN1 ACTN1 MSLNL MSLNL ADAMTS12 ADAMTS12 EPDR1 EPDR1 ITGA3 ITGA3 SRC SRC EDA EDA TNXB TNXB ITGB1 ITGB1 DDR1 DDR1 ITGAV ITGAV ITGA6 ITGA6 CD96 CD96 ITGAE ITGAE CTNNB1 CTNNB1 COL3A1 COL3A1 ITGB1BP1 ITGB1BP1 CCL21 CCL21 ITGA7 ITGA7 SRF SRF MADCAM1 MADCAM1 CCN2 CCN2 EMP2 EMP2 CD34 CD34 PTPRK PTPRK ITGA10 ITGA10 A0A287AB18_PIG A0A287AB18_PIG ITGA4 ITGA4 ITGB7 ITGB7 BCR BCR ITGB6 ITGB6 ITGB2 ITGB2 NID2 NID2 RCC2 RCC2 RHOA RHOA ITGB8 ITGB8 ITGB5 ITGB5 ITGBL1 ITGBL1 THY1 THY1 MUC4 MUC4 ITGA11 ITGA11 MKLN1 MKLN1 BCAM BCAM TNN TNN FREM1 FREM1 CORO2A CORO2A FERMT3 FERMT3 SNED1 SNED1 AJUBA AJUBA EMILIN1 EMILIN1 TECTA TECTA L1CAM L1CAM FERMT2 FERMT2 PXN PXN ACTN2 ACTN2 ITGA1 ITGA1 PIP5K1A PIP5K1A ITGB4 ITGB4 ITGB3 ITGB3 TSC1 TSC1 ACTN3 ACTN3 COL13A1 COL13A1 PEAK1 PEAK1 ANGPTL3 ANGPTL3 TRPM7 TRPM7 CORO2B CORO2B FERMT1 FERMT1 ITGAM ITGAM ITGAL ITGAL OTOA OTOA LOC100524016 LOC100524016 ITGA5 ITGA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL2L11Uncharacterized protein. (433 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (534 aa)
HPSEHeparanase isoform 1 preproprotein. (551 aa)
THSD1Thrombospondin type 1 domain containing 1. (858 aa)
NID1Nidogen 1. (1309 aa)
VWA2Von Willebrand factor A domain containing 2. (735 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
BCL6B-cell lymphoma 6 protein isoform X1. (706 aa)
COL5A3Collagen type V alpha 3 chain. (1747 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (819 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
ZYXZyxin. (588 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1178 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
ILKIntegrin linked kinase. (479 aa)
VTNVitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa)
FGGFibrinogen gamma chain. (454 aa)
TAOK2TAO kinase 2. (1241 aa)
RHODRas homolog family member D. (203 aa)
ACTN1Uncharacterized protein. (888 aa)
MSLNLMesothelin like. (716 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
EPDR1Ependymin related 1. (234 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1085 aa)
SRCTyrosine-protein kinase. (559 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (389 aa)
TNXBUncharacterized protein. (4137 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa)
DDR1Tyrosine-protein kinase receptor. (1005 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa)
CD96CD96 molecule. (571 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1168 aa)
CTNNB1Catenin beta 1. (808 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1471 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (270 aa)
CCL21Putative CCL21 chemokine. (134 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1169 aa)
SRFSerum response factor. (512 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1 isoform a. (390 aa)
CCN2CCN family member 2; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation- dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity). (354 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
CD34CD34 molecule. (393 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1554 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1352 aa)
A0A287AB18_PIGUncharacterized protein. (385 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1055 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (882 aa)
BCRBCR activator of RhoGEF and GTPase. (1274 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (854 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (903 aa)
NID2Nidogen 2. (1348 aa)
RCC2Regulator of chromosome condensation 2. (554 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (722 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ITGBL1Integrin subunit beta like 1. (507 aa)
THY1Thy-1 cell surface antigen. (165 aa)
MUC4Uncharacterized protein. (1173 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1282 aa)
MKLN1Muskelin 1. (754 aa)
BCAMBasal cell adhesion molecule (Lutheran blood group). (770 aa)
TNNTenascin N. (1472 aa)
FREM1FRAS1 related extracellular matrix 1. (2182 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (505 aa)
FERMT3Fermitin family member 3. (667 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1413 aa)
AJUBAAjuba LIM protein. (565 aa)
EMILIN1Elastin microfibril interfacer 1. (1292 aa)
TECTATectorin alpha. (2469 aa)
L1CAML1 cell adhesion molecule. (1256 aa)
FERMT2Fermitin family member 2. (776 aa)
PXNUncharacterized protein. (1072 aa)
ACTN2Uncharacterized protein. (933 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1175 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (584 aa)
ITGB4Integrin beta. (1814 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (835 aa)
TSC1TSC complex subunit 1. (1166 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (931 aa)
COL13A1Collagen type XIII alpha 1 chain. (726 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1748 aa)
ANGPTL3Fibrinogen C-terminal domain-containing protein. (461 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1886 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (554 aa)
FERMT1Fermitin family member 1. (676 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1272 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1235 aa)
OTOAOtoancorin. (1133 aa)
LOC100524016Uncharacterized protein. (593 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1057 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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