STRINGSTRING
PLXNB3 PLXNB3 PPARA PPARA WNT1 WNT1 ACVRL1 ACVRL1 LAG3 LAG3 ADTRP ADTRP RIPOR2 RIPOR2 NOTCH4 NOTCH4 LRRC1 LRRC1 DEF6 DEF6 F1RMG9_PIG F1RMG9_PIG ARG2 ARG2 IL4I1 IL4I1 EPHB2 EPHB2 SMAD7 SMAD7 THBS1 THBS1 CORO2B CORO2B BMP4 BMP4 CD274 CD274 ANXA1 ANXA1 NRARP NRARP F1S1H9_PIG F1S1H9_PIG MUC1 MUC1 ADAM15 ADAM15 VTCN1 VTCN1 PTPN22 PTPN22 DLC1 DLC1 IDO1 IDO1 JAG1 JAG1 TMEM131L TMEM131L AP1AR AP1AR DMTN DMTN SH2B3 SH2B3 NF2 NF2 ADORA2A ADORA2A PPM1F PPM1F VSIR VSIR PLXNB1 PLXNB1 HRG HRG BCL6 BCL6 MELTF MELTF CD80 CD80 DSCAM DSCAM ARHGAP6 ARHGAP6 IRF1 IRF1 IL4 IL4 LAX1 LAX1 SEMA3E SEMA3E FGL2 FGL2 IL10 IL10 ZNF703 ZNF703 FZD7 FZD7 IHH IHH EPHA4 EPHA4 SHH SHH PODXL PODXL GLI3 GLI3 CCL28 CCL28 TBCD TBCD FOXJ1 FOXJ1 ERBB2 ERBB2 TBX21 TBX21 NF1 NF1 AKNA AKNA ERBB3 ERBB3 LOC110255214 LOC110255214 CORO1C CORO1C PLXNA2 PLXNA2 HOXA7 HOXA7 SOCS1 SOCS1 PIK3R1 PIK3R1 CBLL1 CBLL1 MARCHF7 MARCHF7 MAD2L2 MAD2L2 LPXN LPXN CD9 CD9 HAVCR2 HAVCR2 I3LQK7_PIG I3LQK7_PIG PHLDB2 PHLDB2 SERPINE1 SERPINE1 C1QTNF6 C1QTNF6 PLXNA3 PLXNA3 ATP5F1B ATP5F1B CD86 CD86 CD300A CD300A APOD APOD SEMA4D SEMA4D ALOX15 ALOX15 TGFB1 TGFB1 DUSP1 DUSP1 DLG1 DLG1 CTLA4 CTLA4 PLXNA4 PLXNA4 GPNMB GPNMB ILDR2 ILDR2 PLA2G2F PLA2G2F APOA1 APOA1 SPOCK1 SPOCK1 TIGIT TIGIT EFNA5 EFNA5 ITGB1BP1 ITGB1BP1 PLET1 PLET1 A0A286ZWW0_PIG A0A286ZWW0_PIG PDE3B PDE3B PTPN6 PTPN6 CCL21 CCL21 FGL1 FGL1 EPB41L5 EPB41L5 BMP2 BMP2 CRTAM CRTAM PLXNC1 PLXNC1 SNAI2 SNAI2 ACER2 ACER2 PLA2G2D PLA2G2D MAD1L1 MAD1L1 GCNT2 GCNT2 PLXNA1 PLXNA1 LRRC32 LRRC32 ACTN4 ACTN4 PTPRC PTPRC ASS1 ASS1 MYOC MYOC RC3H1 RC3H1 PRKG1 PRKG1 VSIG4 VSIG4 ITCH ITCH SOCS6 SOCS6 PRKAR1A PRKAR1A TSPAN32 TSPAN32 MAPK7 MAPK7 FBLN1 FBLN1 LGALS9 LGALS9 RCC2 RCC2 A0A287ANH8_PIG A0A287ANH8_PIG RHOA RHOA CEBPB CEBPB C1QTNF1 C1QTNF1 LGALS7 LGALS7 PAWR PAWR ADIPOQ ADIPOQ CBLB CBLB PAG1 PAG1 A0A287AXM5_PIG A0A287AXM5_PIG SERPINE2 SERPINE2 A0A287AZ68_PIG A0A287AZ68_PIG NDFIP1 NDFIP1 TNFRSF21 TNFRSF21 FOXP3 FOXP3 NOTCH1 NOTCH1 CD74 CD74 PELI1 PELI1 SEMA6A SEMA6A UBASH3B UBASH3B ABL1 ABL1 PRKCD PRKCD ZC3H12A ZC3H12A KANK1 KANK1 SPINT2 SPINT2 BMP6 BMP6 CORO2A CORO2A CYP1B1 CYP1B1 NEXMIF NEXMIF RC3H2 RC3H2 ZC3H8 ZC3H8 AJAP1 AJAP1 ABCA12 ABCA12 HFE HFE CDH1 CDH1 PTPN2 PTPN2 ADAMTS18 ADAMTS18 ZBTB7B ZBTB7B IL2 IL2 RND1 RND1 FZD4 FZD4 CDH13 CDH13 RASA1 RASA1 SWAP70 SWAP70 TNR TNR MBP MBP DLG2 DLG2 A0A5G2QF80_PIG A0A5G2QF80_PIG TRPV4 TRPV4 PDCD1LG2 PDCD1LG2 PTPN11 PTPN11 GLMN GLMN YTHDF2 YTHDF2 NCKAP1L NCKAP1L COL1A1 COL1A1 CXCL12 CXCL12 LOXL3 LOXL3 ADAM10 ADAM10 ANGPT2 ANGPT2 TWSG1 TWSG1 CCL25 CCL25 CLEC4G CLEC4G MYADM MYADM PLXND1 PLXND1 KNG1 KNG1 JAM3 JAM3 SPRY4 SPRY4 TARM1 TARM1 CASK CASK CBFB CBFB DLG5 DLG5 TNFAIP8L2 TNFAIP8L2 HLX HLX SOCS5 SOCS5 DUSP3 DUSP3 B4GALNT2 B4GALNT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXNB3Plexin B3. (1894 aa)
PPARAUncharacterized protein. (469 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
LAG3Uncharacterized protein. (507 aa)
ADTRPAndrogen dependent TFPI regulating protein. (230 aa)
RIPOR2PL48 domain-containing protein. (1063 aa)
NOTCH4Uncharacterized protein. (1993 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
DEF6Differentially expressed in FDCP 6 homolog. (631 aa)
F1RMG9_PIGUncharacterized protein. (298 aa)
ARG2Arginase. (354 aa)
IL4I1Amine oxidase. (578 aa)
EPHB2EPH receptor B2. (987 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
THBS1Uncharacterized protein. (1170 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (554 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CD274CD274 molecule. (311 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
F1S1H9_PIGPA14 domain-containing protein. (752 aa)
MUC1SEA domain-containing protein. (638 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform 6 preproprotein. (866 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (282 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (821 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
IDO1Uncharacterized protein. (429 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa)
TMEM131LTransmembrane 131 like. (1682 aa)
AP1ARAdaptor related protein complex 1 associated regulatory protein. (280 aa)
DMTNDematin actin binding protein. (405 aa)
SH2B3SH2B adaptor protein 3. (600 aa)
NF2Neurofibromin 2. (586 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (414 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (436 aa)
VSIRV-set immunoregulatory receptor. (310 aa)
PLXNB1Plexin B1. (2133 aa)
HRGUncharacterized protein. (561 aa)
BCL6B-cell lymphoma 6 protein isoform X1. (706 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (737 aa)
CD80CD80 molecule. (297 aa)
DSCAMDS cell adhesion molecule. (2008 aa)
ARHGAP6Rho GTPase activating protein 6. (705 aa)
IRF1Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] (320 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (133 aa)
LAX1Lymphocyte transmembrane adaptor 1. (401 aa)
SEMA3ESemaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa)
FGL2Fibroleukin. (495 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (219 aa)
ZNF703Zinc finger protein 703. (591 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
EPHA4EPH receptor A4. (986 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (516 aa)
GLI3GLI family zinc finger 3. (1586 aa)
CCL28C-C motif chemokine. (176 aa)
TBCDTFCD_C domain-containing protein. (1197 aa)
FOXJ1Forkhead box J1. (421 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
TBX21Uncharacterized protein. (535 aa)
NF1Neurofibromin 1. (2847 aa)
AKNAAT-hook transcription factor. (1429 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1342 aa)
LOC110255214Glyco_trans_2-like domain-containing protein. (506 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (511 aa)
PLXNA2Plexin A2. (1937 aa)
HOXA7Homeobox A7. (234 aa)
SOCS1Suppressor of cytokine signaling 1. (220 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
CBLL1Cbl proto-oncogene like 1. (529 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (708 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
CD9CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, [...] (226 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (283 aa)
I3LQK7_PIGGalectin. (135 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1253 aa)
SERPINE1Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa)
C1QTNF6C1q domain-containing protein. (285 aa)
PLXNA3Plexin A3. (1871 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (570 aa)
CD86T-lymphocyte activation antigen CD86 isoform 1. (337 aa)
CD300ACMRF35-like molecule 8 isoform 1. (309 aa)
APODApolipoprotein D. (228 aa)
SEMA4DSemaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa)
ALOX15Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (786 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (353 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CTLA4Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. (223 aa)
PLXNA4Plexin-A4 isoform X1. (1893 aa)
GPNMBGlycoprotein nmb. (565 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (641 aa)
PLA2G2FPhospholipase A(2). (302 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa)
SPOCK1SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (439 aa)
TIGITT cell immunoreceptor with Ig and ITIM domains. (223 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (270 aa)
PLET1Placenta-expressed transcript 1 protein; Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle (By similarity). (202 aa)
A0A286ZWW0_PIGAIG1-type G domain-containing protein. (321 aa)
PDE3BPhosphodiesterase. (1117 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (612 aa)
CCL21Putative CCL21 chemokine. (134 aa)
FGL1Fibrinogen like 1. (315 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (731 aa)
BMP2Bone morphogenetic protein 2 preproprotein. (395 aa)
CRTAMCytotoxic and regulatory T cell molecule. (400 aa)
PLXNC1Plexin C1. (1612 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (274 aa)
PLA2G2DPhospholipase A(2). (161 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (737 aa)
GCNT2Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa)
PLXNA1Plexin A1. (1909 aa)
LRRC32Leucine rich repeat containing 32. (688 aa)
ACTN4Actinin alpha 4. (1160 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1092 aa)
ASS1Argininosuccinate synthase 1. (428 aa)
MYOCMyocilin. (489 aa)
RC3H1Ring finger and CCCH-type domains 1. (1132 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
VSIG4V-set and immunoglobulin domain containing 4. (399 aa)
ITCHE3 ubiquitin-protein ligase. (873 aa)
SOCS6Suppressor of cytokine signaling 6 isoform X1. (535 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. (433 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (239 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (840 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (819 aa)
LGALS9Uncharacterized protein. (450 aa)
RCC2Regulator of chromosome condensation 2. (554 aa)
A0A287ANH8_PIGUncharacterized protein. (466 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
C1QTNF1C1q and TNF related 1. (273 aa)
LGALS7Galectin. (138 aa)
PAWRPro-apoptotic WT1 regulator. (336 aa)
ADIPOQC1q domain-containing protein. (332 aa)
CBLBE3 ubiquitin-protein ligase CBL-B isoform X1. (1047 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (435 aa)
A0A287AXM5_PIGPA14 domain-containing protein. (723 aa)
SERPINE2SERPIN domain-containing protein; Belongs to the serpin family. (378 aa)
A0A287AZ68_PIGPDZ domain-containing protein. (909 aa)
NDFIP1Uncharacterized protein. (254 aa)
TNFRSF21TNF receptor superfamily member 21. (813 aa)
FOXP3Forkhead box protein P3 isoform a. (475 aa)
NOTCH1Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
CD74Thyroglobulin type-1 domain-containing protein. (347 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
SEMA6ASemaphorin-6A isoform 1; Belongs to the semaphorin family. (1047 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (638 aa)
ABL1Tyrosine-protein kinase. (1146 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (582 aa)
KANK1KN motif and ankyrin repeat domains 1. (1331 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (252 aa)
BMP6TGF_BETA_2 domain-containing protein. (537 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (505 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
NEXMIFNeurite extension and migration factor. (1514 aa)
RC3H2Ring finger and CCCH-type domains 2. (1192 aa)
ZC3H8Zinc finger CCCH-type containing 8. (309 aa)
AJAP1Adherens junctions associated protein 1. (527 aa)
ABCA12ATP binding cassette subfamily A member 12. (2593 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (395 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (925 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (447 aa)
ADAMTS18ADAM metallopeptidase with thrombospondin type 1 motif 18. (1223 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B isoform X1. (543 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa)
RND1Rho family GTPase 1. (244 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa)
CDH13Uncharacterized protein. (771 aa)
RASA1RAS p21 protein activator 1. (1040 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
TNRTenascin R. (1270 aa)
MBPMyelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). (295 aa)
DLG2Discs large MAGUK scaffold protein 2. (1012 aa)
A0A5G2QF80_PIGUncharacterized protein. (287 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (924 aa)
PDCD1LG2IG domain-containing protein. (290 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
GLMNGlomulin, FKBP associated protein. (613 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
NCKAP1LNCK associated protein 1 like. (1128 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
LOXL3Lysyl oxidase like 3. (814 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion [...] (748 aa)
ANGPT2Angiopoietin-2; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell- matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). (495 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (291 aa)
CCL25C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa)
CLEC4GC-type lectin domain-containing protein. (358 aa)
MYADMMyeloid associated differentiation marker. (391 aa)
PLXND1Plexin D1. (1926 aa)
KNG1Kininogen 1. (630 aa)
JAM3Junctional adhesion molecule 3. (360 aa)
SPRY4Sprouty RTK signaling antagonist 4. (325 aa)
TARM1T cell-interacting, activating receptor on myeloid cells 1. (265 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (925 aa)
CBFBCore-binding factor subunit beta. (204 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1920 aa)
TNFAIP8L2Tumor necrosis factor alpha-induced protein 8-like 2. (184 aa)
HLXH2.0 like homeobox. (556 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
B4GALNT2Glyco_trans_2-like domain-containing protein. (656 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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