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| | BTBD11 | Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform a. (1108 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa) |
| | GDF11 | Growth/differentiation factor 11 preproprotein. (404 aa) |
| | INHBE | Inhibin subunit beta E. (350 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (924 aa) |
| | GDF3 | Growth differentiation factor 3. (363 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (668 aa) |
| | PML | Promyelocytic leukemia. (827 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. (581 aa) |
| | ETV2 | ETS variant 2. (242 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2789 aa) |
| | BMP8B | TGF_BETA_2 domain-containing protein. (401 aa) |
| | BMP8A | TGF_BETA_2 domain-containing protein. (360 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog 4; Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in r [...] (552 aa) |
| | ONECUT2 | One cut domain family member. (694 aa) |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | SPTBN5 | Spectrin beta, non-erythrocytic 5. (3616 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (496 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | FOXH1 | Forkhead box H1. (354 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa) |
| | BMP7 | Bone morphogenetic protein 7. (650 aa) |
| | ZNF831 | Zinc finger protein 831. (1649 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (315 aa) |
| | CCDC142 | Coiled-coil domain containing 142. (768 aa) |
| | MSX1 | Homeobox domain-containing protein. (303 aa) |
| | AFP | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. (610 aa) |
| | SFRP2 | Uncharacterized protein. (294 aa) |
| | SMAD9 | Mothers against decapentaplegic homolog. (467 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase NAD(+) isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | HNF1A | Hepatocyte nuclear factor 1-alpha isoform 2. (631 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1065 aa) |
| | GDF2 | Growth differentiation factor 2. (427 aa) |
| | GDF10 | Growth differentiation factor 10. (480 aa) |
| | LOC100524517 | Left-right determination factor. (373 aa) |
| | SKIL | Ski-like protein isoform X1. (661 aa) |
| | F1S1P4_PIG | PC4 domain-containing protein. (120 aa) |
| | ZCCHC18 | Zinc finger CCHC-type containing 18. (378 aa) |
| | FSHB | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa) |
| | COMP | Cartilage oligomeric matrix protein. (756 aa) |
| | GDF1 | Uncharacterized protein. (363 aa) |
| | RGMB | Repulsive guidance molecule BMP co-receptor b. (480 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) |
| | COL1A2 | Fibrillar collagen NC1 domain-containing protein. (1135 aa) |
| | ADAM9 | Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (819 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | MSTN | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa) |
| | CFC1B | EGF-like domain-containing protein. (210 aa) |
| | ZYX | Zyxin. (588 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa) |
| | FST | Follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). (343 aa) |
| | STAT3 | Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (580 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | MTMR4 | Myotubularin related protein 4. (1205 aa) |
| | FAM83G | Family with sequence similarity 83 member G. (812 aa) |
| | DSG4 | Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1042 aa) |
| | TMPRSS6 | Transmembrane serine protease 6; Belongs to the peptidase S1 family. (812 aa) |
| | LEFTY2 | Left-right determination factor. (366 aa) |
| | EID2 | EP300 interacting inhibitor of differentiation 2. (178 aa) |
| | GDF7 | Growth differentiation factor 7. (449 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family. (364 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | LOC102162178 | USP domain-containing protein; Belongs to the peptidase C19 family. (690 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1208 aa) |
| | BMPR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | LOC100625207 | USP domain-containing protein; Belongs to the peptidase C19 family. (2554 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | GLG1 | Golgi glycoprotein 1. (1210 aa) |
| | BMP3 | TGF_BETA_2 domain-containing protein. (719 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (186 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (604 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | SRC | Tyrosine-protein kinase. (559 aa) |
| | ENG | Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] (619 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | CHRDL1 | Chordin like 1. (526 aa) |
| | TGFB3 | Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi appa [...] (456 aa) |
| | TGFBR1 | TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] (560 aa) |
| | INHBC | Inhibin beta C chain preproprotein. (354 aa) |
| | GDF15 | Growth differentiation factor 15. (308 aa) |
| | ZNF8 | Zinc finger protein 8. (616 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2365 aa) |
| | JADE2 | Jade family PHD finger 2. (784 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | LOC100512195 | PC4 domain-containing protein. (127 aa) |
| | COL3A1 | Collagen alpha-1(III) chain preproprotein. (1471 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (429 aa) |
| | AKAP3 | A-kinase (PRKA) anchor protein 3. (854 aa) |
| | TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa) |
| | LOC110261493 | Lymphocyte antigen 6 complex locus G6E. (133 aa) |
| | AKAP4 | A-kinase anchoring protein 4. (863 aa) |
| | BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | NCEH1 | Neutral cholesterol ester hydrolase 1 isoform b. (408 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa) |
| | APPL1 | Adaptor protein phosphotyrosine interaction PH domain and leucine zipper containing 1. (708 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1554 aa) |
| | GCNT2 | Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa) |
| | BMP10 | Bone morphogenetic protein 10 preproprotein. (423 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (688 aa) |
| | HEXA | Beta-hexosaminidase. (545 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | USP9X | Putative ubiquitin carboxyl-terminal hydrolase FAF-X isoform X4; Belongs to the peptidase C19 family. (2554 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (797 aa) |
| | TGFBR3L | Transforming growth factor beta receptor 3 like. (285 aa) |
| | SKI | SKI proto-oncogene. (728 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (554 aa) |
| | DLX5 | Homeobox protein DLX-5. (290 aa) |
| | PDCD4 | Programmed cell death protein 4 isoform 1. (469 aa) |
| | SOST | Sclerostin. (212 aa) |
| | CDH5 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] (782 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (748 aa) |
| | HES1 | Uncharacterized protein. (280 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (722 aa) |
| | NODAL | Nodal growth differentiation factor. (316 aa) |
| | SUB1 | SUB1 regulator of transcription. (127 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (656 aa) |
| | TBXT | T-box transcription factor T. (435 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (432 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa) |
| | SCX | Basic helix-loop-helix transcription factor scleraxis. (310 aa) |
| | RBM14 | RNA-binding protein 14 isoform 1. (669 aa) |
| | INHBA | Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (424 aa) |
| | RNF111 | Ring finger protein 111. (992 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (1028 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (519 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | ABL1 | Tyrosine-protein kinase. (1146 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (226 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP- 1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and m [...] (472 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (704 aa) |
| | BMP6 | TGF_BETA_2 domain-containing protein. (537 aa) |
| | ACVR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (729 aa) |
| | NANOG | Homeobox domain-containing protein. (304 aa) |
| | ZFYVE9 | Zinc finger FYVE domain-containing protein. (1422 aa) |
| | GDF6 | Growth/differentiation factor 6 preproprotein. (459 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1332 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa) |
| | SPART | Spartin. (666 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (395 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (456 aa) |
| | INHBB | Inhibin beta B chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (407 aa) |
| | AMH | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). (577 aa) |
| | SLC33A1 | Solute carrier family 33 member 1. (751 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | FGF9 | Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa) |
| | ARRB2 | Arrestin beta 2. (493 aa) |
| | AMHR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (583 aa) |
| | TMEM100 | Transmembrane protein 100 isoform X1. (134 aa) |
| | FERMT2 | Fermitin family member 2. (776 aa) |
| | PXN | Uncharacterized protein. (1072 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (229 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (611 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (505 aa) |
| | ACVR2B | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] (565 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (291 aa) |
| | BMPER | BMP binding endothelial regulator. (699 aa) |
| | HIVEP1 | Human immunodeficiency virus type I enhancer binding protein 1. (2721 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (859 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1622 aa) |
| | TGFBR3 | Transforming growth factor beta receptor type 3; Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. (952 aa) |
| | RUNX2 | Runt-related transcription factor 2 isoform a. (625 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) |
| | PPM1L | Protein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (547 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (434 aa) |
| | TF-2 | Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (702 aa) |
