STRINGSTRING
MYOZ2 MYOZ2 SVIL SVIL DES DES MYLK2 MYLK2 UNC45A UNC45A CD164 CD164 UNC45B UNC45B CACNA1S CACNA1S TRIM72 TRIM72 C9orf24 C9orf24 COL19A1 COL19A1 MYORG MYORG BIN3 BIN3 MYF5 MYF5 SAP30 SAP30 SRPK3 SRPK3 DMD DMD PKP2 PKP2 CNTF CNTF ZNF764 ZNF764 KEL KEL EMD EMD RYR2 RYR2 MYLPF MYLPF FOXL2 FOXL2 HLX HLX ARID5B ARID5B SELENON SELENON MYF6 MYF6 LOC102158424 LOC102158424 HOMER1 HOMER1 MTM1 MTM1 S1PR1 S1PR1 MYL2 MYL2 HEYL HEYL SOX8 SOX8 PITX1 PITX1 WNT10B WNT10B DSP DSP RIPOR2 RIPOR2 STRA6 STRA6 CFL2 CFL2 NR2F2 NR2F2 GSC GSC VRK3 VRK3 CITED2 CITED2 HEY2 HEY2 VGLL2 VGLL2 POPDC3 POPDC3 SMAD7 SMAD7 SMAD4 SMAD4 ACTC1 ACTC1 SIX1 SIX1 FOXH1 FOXH1 ZFPM2 ZFPM2 JPH1 JPH1 MSC MSC CHD7 CHD7 FRG1 FRG1 MYL10 MYL10 PRR14 PRR14 SMYD1 SMYD1 MSX1 MSX1 EDNRA EDNRA PPP3CA PPP3CA RB1 RB1 EGLN1 EGLN1 EGR2 EGR2 MYOZ1 MYOZ1 ACTA2 ACTA2 VAX1 VAX1 KLHL40 KLHL40 MYL3 MYL3 KY KY POPDC2 POPDC2 CSRP3 CSRP3 MYOD1 MYOD1 MEF2C MEF2C WT1 WT1 STAC3 STAC3 SGCE SGCE CDK5 CDK5 SHOX2 SHOX2 DMRTA2 DMRTA2 EP300 EP300 EID2 EID2 WNT3A WNT3A KRAS KRAS LBX1 LBX1 SPG11 SPG11 CDON CDON FXR1 FXR1 MAFF MAFF I3LLG5_PIG I3LLG5_PIG ACTN1 ACTN1 DLL1 DLL1 TNNT2 TNNT2 MKX MKX PPP3CB PPP3CB ENG ENG TGFB1 TGFB1 FHL1 FHL1 ITGB1 ITGB1 TGFBR1 TGFBR1 TNNI1 TNNI1 CAV1 CAV1 EGR1 EGR1 MEOX2 MEOX2 ATF3 ATF3 CCNT2 CCNT2 CHRNA1 CHRNA1 HOXD10 HOXD10 HOXD9 HOXD9 DNER DNER CHRND CHRND SHH SHH SMO SMO CAV2 CAV2 TBX20 TBX20 ISL1 ISL1 MED1 MED1 HLF HLF NF1 NF1 COL3A1 COL3A1 TCF15 TCF15 SIX4 SIX4 USP2 USP2 LIF LIF NPHS1 NPHS1 BMP2 BMP2 ASB2 ASB2 ALX4 ALX4 WNT5A WNT5A GTF3C5 GTF3C5 BMP10 BMP10 FOXN2 FOXN2 PAX5 PAX5 HIVEP3 HIVEP3 BMPR1A BMPR1A MYLK MYLK R3HDM1 R3HDM1 DISP1 DISP1 HAND1 HAND1 NKX2-5 NKX2-5 TCAP TCAP FZD2 FZD2 MEF2D MEF2D KLHL41 KLHL41 TNNC1 TNNC1 CPT1B CPT1B ZNF689 ZNF689 R3HDM2 R3HDM2 NR4A1 NR4A1 METTL8 METTL8 KLF5 KLF5 RHOA RHOA ANKRD1 ANKRD1 CRYAB CRYAB LEMD2 LEMD2 VAMP5 VAMP5 MYOG MYOG P2RX2 P2RX2 ELN ELN XBP1 XBP1 CAVIN4 CAVIN4 LRP2 LRP2 ZFPM1 ZFPM1 NOTCH1 NOTCH1 SCX SCX A0A287B5X4_PIG A0A287B5X4_PIG WNT2 WNT2 GPCPD1 GPCPD1 PROX1 PROX1 TCF21 TCF21 PLEC PLEC BVES BVES POU4F1 POU4F1 ID3 ID3 NOG NOG ZBTB18 ZBTB18 DAG1 DAG1 DLL4 DLL4 ANKRD33B ANKRD33B SMTNL1 SMTNL1 ACTA1 ACTA1 ADARB1 ADARB1 TMEM182 TMEM182 KMT5B KMT5B BCL9L BCL9L PHOX2B PHOX2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYOZ2Calsarcin 1. (264 aa)
SVILSupervillin. (2229 aa)
DESDesmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-ancho [...] (471 aa)
MYLK2Myosin light chain kinase 2. (652 aa)
UNC45AUnc-45 myosin chaperone A. (1084 aa)
CD164Sialomucin core protein 24 isoform 1. (194 aa)
UNC45BUNC45-central domain-containing protein. (919 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
TRIM72Tripartite motif-containing protein 72. (478 aa)
C9orf24Chromosome 9 open reading frame 24. (262 aa)
COL19A1Collagen type XIX alpha 1 chain. (1132 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (713 aa)
BIN3Bridging integrator 3. (324 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (253 aa)
SAP30Histone deacetylase complex subunit SAP30. (221 aa)
SRPK3SRSF protein kinase 3; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity). (604 aa)
DMDDystrophin; Anchors the extracellular matrix to the cytoskeleton via F- actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. (3679 aa)
PKP2Plakophilin 2. (837 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy (By similarity). (619 aa)
ZNF764Uncharacterized protein. (408 aa)
KELKell metallo-endopeptidase (Kell blood group). (763 aa)
EMDLEM domain-containing protein. (400 aa)
RYR2Ryanodine receptor 2. (4966 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (209 aa)
FOXL2Forkhead box protein L2; Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity). Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells (By similarity). Suppresses ESR1- mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Activates SIRT1 transcription under cellular stress conditions (By similarity). Activates [...] (270 aa)
HLXH2.0 like homeobox. (556 aa)
ARID5BAT-rich interaction domain 5B. (1194 aa)
SELENONSelenoprotein N. (556 aa)
MYF6Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). (249 aa)
LOC102158424Uncharacterized protein; Belongs to the actin family. (466 aa)
HOMER1Homer scaffold protein 1. (365 aa)
MTM1Myotubularin isoform X3. (603 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
SOX8SRY-box transcription factor 8. (460 aa)
PITX1Homeobox protein. (314 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
DSPDesmoplakin. (2883 aa)
RIPOR2PL48 domain-containing protein. (1063 aa)
STRA6Stimulated by retinoic acid 6. (666 aa)
CFL2Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity). (166 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
GSCGoosecoid homeobox. (256 aa)
VRK3VRK serine/threonine kinase 3. (513 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
VGLL2Vestigial like family member 2. (319 aa)
POPDC3Popeye domain-containing protein 3. (291 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD4Mothers against decapentaplegic homolog 4; Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in r [...] (552 aa)
ACTC1Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa)
SIX1Six homeobox 1. (284 aa)
FOXH1Forkhead box H1. (354 aa)
ZFPM2Uncharacterized protein. (1153 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (656 aa)
MSCMusculin. (201 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2863 aa)
FRG1FSHD region gene 1. (257 aa)
MYL10Myosin light chain 10. (167 aa)
PRR14Proline rich 14. (705 aa)
SMYD1SET and MYND domain containing 1. (539 aa)
MSX1Homeobox domain-containing protein. (303 aa)
EDNRAEndothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity). (427 aa)
PPP3CASerine/threonine-protein phosphatase. (523 aa)
RB1RB transcriptional corepressor 1. (938 aa)
EGLN1Uncharacterized protein. (427 aa)
EGR2E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity); Belongs to the EGR C2H2-type zinc-finger protein family. (471 aa)
MYOZ1Myozenin-1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis (By similarity). (297 aa)
ACTA2Actin alpha 2, smooth muscle. (386 aa)
VAX1Ventral anterior homeobox 1. (333 aa)
KLHL40Kelch like family member 40. (623 aa)
MYL3Uncharacterized protein. (196 aa)
KYKyphoscoliosis peptidase. (662 aa)
POPDC2Popeye domain-containing protein 2 isoform 1. (368 aa)
CSRP3Uncharacterized protein. (200 aa)
MYOD1Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa)
MEF2CMyocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa)
WT1Wilms tumor protein homolog; Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isofor [...] (523 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
SGCESarcoglycan epsilon. (473 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
SHOX2Short stature homeobox 2. (321 aa)
DMRTA2Doublesex-and mab-3-related transcription factor A2. (535 aa)
EP300E1A binding protein p300. (2420 aa)
EID2EP300 interacting inhibitor of differentiation 2. (178 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LBX1Ladybird homeobox 1. (281 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2467 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X1. (677 aa)
MAFFMAF bZIP transcription factor F. (166 aa)
I3LLG5_PIGUncharacterized protein. (131 aa)
ACTN1Uncharacterized protein. (888 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (729 aa)
TNNT2Uncharacterized protein. (295 aa)
MKXMohawk homeobox. (351 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
ENGEndoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] (619 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
FHL1Four and a half LIM domains 1. (450 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa)
TGFBR1TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] (560 aa)
TNNI1Troponin I1, slow skeletal type. (228 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (177 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
MEOX2Homeobox domain-containing protein. (303 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3 isoform X1. (250 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (618 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (457 aa)
HOXD10Homeobox protein Hox-D10. (410 aa)
HOXD9Homeobox D9. (351 aa)
DNERDelta/notch like EGF repeat containing. (738 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (502 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa)
TBX20T-box transcription factor TBX20 isoform 1. (449 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
NF1Neurofibromin 1. (2847 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1471 aa)
TCF15Transcription factor 15. (197 aa)
SIX4Homeobox domain-containing protein. (785 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (668 aa)
LIFLeukemia inhibitory factor isoform X1. (202 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1239 aa)
BMP2Bone morphogenetic protein 2 preproprotein. (395 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (607 aa)
ALX4ALX homeobox 4. (406 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
GTF3C5Uncharacterized protein. (551 aa)
BMP10Bone morphogenetic protein 10 preproprotein. (423 aa)
FOXN2Forkhead box protein N2 isoform X1. (439 aa)
PAX5Paired box 5. (390 aa)
HIVEP3Uncharacterized protein. (591 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYLKMyosin light chain kinase, smooth muscle; Phosphorylates a specific serine in the N-terminus of a myosin light chain. Also regulates actin-myosin interaction through a non-kinase activity (By similarity). (1981 aa)
R3HDM1R3H domain-containing protein 1 isoform X1. (1134 aa)
DISP1Dispatched RND transporter family member 1. (1590 aa)
HAND1Heart and neural crest derivatives expressed 1. (218 aa)
NKX2-5NK2 homeobox 5. (323 aa)
TCAPUncharacterized protein. (262 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa)
MEF2DMyocyte enhancer factor 2D. (531 aa)
KLHL41Kelch like family member 41. (601 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (184 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform. (807 aa)
ZNF689Zinc finger protein 689. (500 aa)
R3HDM2Uncharacterized protein. (1079 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1 isoform 2. (598 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (426 aa)
KLF5Uncharacterized protein. (457 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
ANKRD1Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes (By similarity). (339 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (237 aa)
LEMD2LEM domain containing 2. (527 aa)
VAMP5Vesicle associated membrane protein 5. (118 aa)
MYOGMyogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] (215 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (459 aa)
ELNElastin. (674 aa)
XBP1BZIP domain-containing protein. (378 aa)
CAVIN4Muscle-related coiled-coil protein. (362 aa)
LRP2Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4626 aa)
ZFPM1Zinc finger protein, FOG family member 1. (965 aa)
NOTCH1Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
SCXBasic helix-loop-helix transcription factor scleraxis. (310 aa)
A0A287B5X4_PIGUncharacterized protein. (100 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
GPCPD1Glycerophosphocholine phosphodiesterase GPCPD1. (672 aa)
PROX1Prospero homeobox 1. (737 aa)
TCF21Transcription factor 21. (179 aa)
PLECPlectin. (5422 aa)
BVESBlood vessel epicardial substance; Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epitheli [...] (360 aa)
POU4F1POU domain protein. (421 aa)
ID3BHLH domain-containing protein. (118 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ZBTB18Zinc finger and BTB domain-containing protein 18 isoform X1. (531 aa)
DAG1Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (912 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
ANKRD33BAnkyrin repeat domain-containing protein 33B. (490 aa)
SMTNL1Calponin-homology (CH) domain-containing protein. (182 aa)
ACTA1Actin, alpha skeletal muscle. (465 aa)
ADARB1Adenosine deaminase RNA specific B1. (702 aa)
TMEM182Transmembrane protein 182 isoform a. (229 aa)
KMT5BLysine methyltransferase 5B. (915 aa)
BCL9LBCL9 like. (1526 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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