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| | SNRPC | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (181 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (1117 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (234 aa) |
| | SRSF9 | Uncharacterized protein. (221 aa) |
| | RBM19 | RNA binding motif protein 19. (940 aa) |
| | ARL6IP4 | ADP ribosylation factor like GTPase 6 interacting protein 4. (238 aa) |
| | SFSWAP | Splicing factor, suppressor of white-apricot homolog isoform 2. (944 aa) |
| | CCAR2 | DBC1 domain-containing protein. (916 aa) |
| | ZC3H13 | Zinc finger CCCH-type containing 13. (1640 aa) |
| | F1RWB7_PIG | CSD_1 domain-containing protein. (264 aa) |
| | DHX15 | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15. (795 aa) |
| | DDX1 | DEAD-box helicase 1. (741 aa) |
| | SF3B6 | Splicing factor 3B subunit 6. (125 aa) |
| | SNRNP200 | U5 small nuclear ribonucleoprotein 200 kDa helicase isoform X1. (2136 aa) |
| | RNPS1 | RNA binding protein with serine rich domain 1. (341 aa) |
| | LUC7L | LUC7 like. (459 aa) |
| | SNRNP25 | Small nuclear ribonucleoprotein U11/U12 subunit 25. (132 aa) |
| | UMOD | Uromodulin. (642 aa) |
| | CD2BP2 | CD2 cytoplasmic tail binding protein 2. (369 aa) |
| | BUD31 | Protein BUD31 homolog isoform X2. (144 aa) |
| | CTNNBL1 | DUF1716 domain-containing protein. (583 aa) |
| | DDX20 | Putative ATP-dependent RNA helicase DDX20 isoform X1. (832 aa) |
| | SCNM1 | Sodium channel modifier 1. (230 aa) |
| | VIRMA | Vir like m6A methyltransferase associated. (1812 aa) |
| | SETX | Senataxin. (2676 aa) |
| | PTBP3 | Polypyrimidine tract-binding protein 3 isoform 3. (557 aa) |
| | PRPF39 | Pre-mRNA processing factor 39. (666 aa) |
| | MAGOH | Mago homolog, exon junction complex subunit. (146 aa) |
| | SRSF11 | Uncharacterized protein. (423 aa) |
| | ZRANB2 | Zinc finger Ran-binding domain-containing protein 2; Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection (By similarity); Belongs to the ZRANB2 family. (316 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa) |
| | SNRNP40 | Small nuclear ribonucleoprotein U5 subunit 40. (355 aa) |
| | SNRPA | U1 small nuclear ribonucleoprotein A; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity). (281 aa) |
| | USB1 | U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (267 aa) |
| | NRDE2 | NRDE-2, necessary for RNA interference, domain containing. (1166 aa) |
| | CDC5L | Cell division cycle 5-like protein. (802 aa) |
| | USP49 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (682 aa) |
| | RBM28 | RNA binding motif protein 28. (758 aa) |
| | SNRPA1 | Small nuclear ribonucleoprotein polypeptide A. (269 aa) |
| | AAR2 | AAR2 splicing factor. (402 aa) |
| | LGALS3 | Galectin. (271 aa) |
| | A0A5G2QJP9_PIG | Uncharacterized protein. (1151 aa) |
| | PTBP1 | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). (647 aa) |
| | WBP11 | WW domain-binding protein 11. (641 aa) |
| | RSRC1 | Arginine and serine rich coiled-coil 1. (334 aa) |
| | A0A5G2QGV3_PIG | Uncharacterized protein. (186 aa) |
| | GEMIN2 | Gem nuclear organelle associated protein 2. (372 aa) |
| | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa) |
| | LOC102162486 | FMC1-LUC7L2 readthrough. (392 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (369 aa) |
| | CLNS1A | Chloride nucleotide-sensitive channel 1A. (236 aa) |
| | BTBD19 | BTB domain containing 19. (290 aa) |
| | PRMT1 | Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (383 aa) |
| | LOC110258135 | Uncharacterized protein. (177 aa) |
| | SRSF4 | Serine and arginine rich splicing factor 4. (489 aa) |
| | CWC15 | CWC15 spliceosome associated protein homolog. (254 aa) |
| | AMH | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). (577 aa) |
| | ARVCF | ARVCF delta catenin family member. (961 aa) |
| | GEMIN7 | Gem nuclear organelle associated protein 7. (131 aa) |
| | DDX39A | DExD-box helicase 39A. (452 aa) |
| | PRPF3 | U4/U6 small nuclear ribonucleoprotein Prp3 isoform 1. (592 aa) |
| | SRSF1 | Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...] (253 aa) |
| | RNF113A | Ring finger protein 113A. (350 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa) |
| | SUGP1 | SURP and G-patch domain containing 1. (633 aa) |
| | GEMIN4 | Gem nuclear organelle associated protein 4. (1059 aa) |
| | DBR1 | Debranching RNA lariats 1. (539 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (755 aa) |
| | ZNF638 | Zinc finger protein 638. (1975 aa) |
| | CELF3 | CUGBP Elav-like family member 3. (495 aa) |
| | DHX38 | DEAH-box helicase 38. (1325 aa) |
| | PRPF40A | Pre-mRNA processing factor 40 homolog A. (994 aa) |
| | SRRM2 | Serine/arginine repetitive matrix 2. (2662 aa) |
| | CDK12 | Cyclin dependent kinase 12. (1483 aa) |
| | PSIP1 | PC4 and SFRS1 interacting protein 1. (530 aa) |
| | THOC7 | THO complex subunit 7 homolog isoform X1. (233 aa) |
| | SREK1 | Splicing regulatory glutamic acid and lysine rich protein 1. (631 aa) |
| | SRPK2 | SRSF protein kinase 2. (763 aa) |
| | RTRAF | RNA transcription, translation and transport factor protein. (261 aa) |
| | ACIN1 | Apoptotic chromatin condensation inducer 1. (1333 aa) |
| | SRSF10 | Serine and arginine rich splicing factor 10. (261 aa) |
| | QKI | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). (338 aa) |
| | IVNS1ABP | Influenza virus NS1A binding protein. (668 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | CELF1 | CUGBP Elav-like family member 1. (551 aa) |
| | RBM14 | RNA-binding protein 14 isoform 1. (669 aa) |
| | SLFNL1 | Schlafen like 1. (422 aa) |
| | TSEN34 | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (350 aa) |
| | NOL3 | Nucleolar protein 3. (237 aa) |
| | ZCRB1 | Zinc finger CCHC-type and RNA binding motif containing 1. (217 aa) |
| | ZMAT5 | Zinc finger matrin-type protein 5. (170 aa) |
| | A0A287B019_PIG | RRM domain-containing protein. (135 aa) |
| | A0A287B004_PIG | RRM domain-containing protein. (337 aa) |
| | A0A287AZB7_PIG | Uncharacterized protein. (65 aa) |
| | YTHDC1 | YTH domain containing 1. (743 aa) |
| | SYF2 | SYF2 pre-mRNA splicing factor. (245 aa) |
| | GEMIN6 | Gem nuclear organelle associated protein 6. (171 aa) |
| | PUF60 | Poly(U)-binding-splicing factor PUF60 isoform a. (587 aa) |
| | CELF4 | CUGBP Elav-like family member 4. (545 aa) |
| | SUGP2 | SURP and G-patch domain containing 2. (1095 aa) |
| | A0A287AVU1_PIG | Uncharacterized protein. (110 aa) |
| | PQBP1 | Polyglutamine binding protein 1. (265 aa) |
| | ESS2 | Ess-2 splicing factor homolog. (521 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (1150 aa) |
| | SRSF7 | Serine/arginine-rich splicing factor 7 isoform 1. (238 aa) |
| | CLP1 | Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (592 aa) |
| | METTL14 | N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa) |
| | THOC5 | THO complex subunit 5 homolog isoform X1. (694 aa) |
| | SF3B3 | Splicing factor 3B subunit 3. (1217 aa) |
| | USP4 | Ubiquitin specific peptidase 4; Belongs to the peptidase C19 family. (979 aa) |
| | MTHFSD | Methenyltetrahydrofolate synthase domain-containing protein isoform 4. (386 aa) |
| | WBP4 | WW domain-binding protein 4. (373 aa) |
| | A0A287ANQ5_PIG | Uncharacterized protein. (412 aa) |
| | PRPF31 | U4/U6 small nuclear ribonucleoprotein Prp31 isoform X1. (499 aa) |
| | A0A287AJR4_PIG | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | MFAP1 | Microfibril associated protein 1. (439 aa) |
| | U2AF1 | Splicing factor U2AF 35 kDa subunit; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron (By similarity). (239 aa) |
| | A0A287AIY4_PIG | RRM domain-containing protein. (246 aa) |
| | SNRNP70 | Small nuclear ribonucleoprotein U1 subunit 70. (436 aa) |
| | RBM4B | RNA-binding protein 4B; Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA (By similarity). (369 aa) |
| | DNAJC17 | DnaJ heat shock protein family (Hsp40) member C17. (309 aa) |
| | MBNL1 | Muscleblind like splicing regulator 1. (436 aa) |
| | SNRPB | Small nuclear ribonucleoprotein-associated protein. (231 aa) |
| | U2AF2 | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa) |
| | PPIL1 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa) |
| | IK | IK cytokine. (554 aa) |
| | CELF5 | CUGBP Elav-like family member 5 isoform X1. (485 aa) |
| | C11orf58 | Chromosome 11 open reading frame 58. (171 aa) |
| | LENG8 | Leukocyte receptor cluster member 8 isoform X1. (917 aa) |
| | KHDC4 | KH domain containing 4, pre-mRNA splicing factor. (489 aa) |
| | DDX41 | DEAD-box helicase 41. (782 aa) |
| | LOC396706 | C3H1-type domain-containing protein. (263 aa) |
| | TSEN15 | tRNA splicing endonuclease subunit 15. (204 aa) |
| | WDR25 | WD repeat domain 25. (536 aa) |
| | SF3A1 | Splicing factor 3a subunit 1. (722 aa) |
| | SNRPB2 | RU2B. (225 aa) |
| | RBM44 | RNA binding motif protein 44. (1056 aa) |
| | PRPF40B | Pre-mRNA processing factor 40 homolog B. (983 aa) |
| | NOVA1 | NOVA alternative splicing regulator 1. (487 aa) |
| | SRSF2 | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5 [...] (221 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (670 aa) |
| | PRMT7 | Protein arginine methyltransferase 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (914 aa) |
| | TARDBP | TAR DNA binding protein. (414 aa) |
| | WTAP | Uncharacterized protein. (649 aa) |
| | DDX47 | Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (493 aa) |
| | GPATCH2L | G patch domain-containing protein 2-like isoform 1. (482 aa) |
| | SFPQ | Splicing factor, proline-and glutamine-rich isoform X1. (702 aa) |
| | TSEN54 | tRNA splicing endonuclease subunit 54. (607 aa) |
| | SCAF1 | SR-related CTD associated factor 1. (1307 aa) |
| | U2AF1L4 | Splicing factor U2AF 35 kDa subunit-like protein isoform 2. (247 aa) |
| | TXNL4A | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | LOC102162880 | Uncharacterized protein. (256 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (972 aa) |
| | SRSF5 | Serine and arginine rich splicing factor 5. (271 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1511 aa) |
| | C19orf54 | Chromosome 19 open reading frame 54. (366 aa) |
| | EIF4A3 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] (488 aa) |
| | ERN1 | Uncharacterized protein. (1029 aa) |
| | SRSF3 | Serine and arginine rich splicing factor 3. (164 aa) |
| | SRPK1 | SRSF protein kinase 1. (831 aa) |
| | DHX16 | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Required for pre-mRNA splicing as component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily. (1062 aa) |
| | SNRNP48 | U11/U12 small nuclear ribonucleoprotein 48 kDa protein. (340 aa) |
| | PRPF4B | Pre-mRNA processing factor 4B. (1056 aa) |
| | SNRPF | Sm domain-containing protein. (86 aa) |
| | MAGOHB | Mago homolog B, exon junction complex subunit. (148 aa) |
| | DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (820 aa) |
| | RTCB | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa) |
| | SNU13 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2. (717 aa) |
| | PNN | Uncharacterized protein. (736 aa) |
| | CDC40 | Pre-mRNA-processing factor 17. (579 aa) |
| | NSRP1 | Nuclear speckle splicing regulatory protein 1. (614 aa) |
| | NOVA2 | NOVA alternative splicing regulator 2. (492 aa) |
| | CELF2 | Uncharacterized protein. (542 aa) |
| | GPATCH2 | G-patch domain containing 2. (492 aa) |
| | HNRNPA1 | Heterogeneous nuclear ribonucleoprotein A1. (373 aa) |
| | RBFOX3 | RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (371 aa) |
| | A0A286ZN96_PIG | RRM domain-containing protein. (90 aa) |
| | A0A286ZN63_PIG | Sm domain-containing protein. (68 aa) |
| | A0A286ZLJ2_PIG | Uncharacterized protein. (178 aa) |
| | DDX17 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. (588 aa) |
| | A0A286ZLE8_PIG | Ribosomal_L7Ae domain-containing protein. (74 aa) |
| | LSM6 | LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (124 aa) |
| | RBFOX2 | RNA binding fox-1 homolog 2. (578 aa) |
| | CWC25 | Pre-mRNA-splicing factor CWC25 homolog. (425 aa) |
| | RBM5 | RNA binding motif protein 5. (893 aa) |
| | PPIE | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (310 aa) |
| | PHF5A | PHD finger protein 5A. (139 aa) |
| | SCAF11 | SR-related CTD associated factor 11. (1398 aa) |
| | AQR | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa) |
| | A0A286ZI50_PIG | RRM domain-containing protein. (184 aa) |
| | SF3B1 | Splicing factor 3B subunit 1 isoform 1. (1304 aa) |
| | DDX39B | Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (467 aa) |
| | FUS | FUS RNA binding protein. (518 aa) |
| | LOC110257929 | RRM domain-containing protein. (307 aa) |
| | FMR1 | Fragile X mental retardation protein 1. (632 aa) |
| | GPKOW | G-patch domain and KOW motifs. (481 aa) |
| | DHX9 | ATP-dependent RNA helicase A. (1384 aa) |
| | RBM10 | RNA binding motif protein 10. (931 aa) |
| | PRR3 | Proline-rich protein 3. (222 aa) |
| | CWF19L2 | CWF19 like cell cycle control factor 2. (856 aa) |
| | PRPF18 | SFM domain-containing protein. (342 aa) |
| | PABPC1 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa) |
| | SNIP1 | Smad nuclear interacting protein 1. (395 aa) |
| | SMNDC1 | Survival motor neuron domain containing 1. (278 aa) |
| | PTBP2 | Polypyrimidine tract binding protein 2. (506 aa) |
| | PRPF38A | Pre-mRNA processing factor 38A. (312 aa) |
| | SNRNP35 | U11/U12 small nuclear ribonucleoprotein 35 kDa protein. (246 aa) |
| | SNRPG | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | NCBP2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa) |
| | RBM22 | RNA binding motif protein 22. (559 aa) |
| | RBMX2 | RRM domain-containing protein. (349 aa) |
| | HNRNPC | Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1. (307 aa) |
| | THRAP3 | Thyroid hormone receptor-associated protein 3 isoform 1. (958 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa) |
| | METTL3 | N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (580 aa) |
| | PPP1R8 | Protein phosphatase 1 regulatory subunit 8. (351 aa) |
| | ZMAT2 | Zinc finger matrin-type 2. (199 aa) |
| | C9orf78 | Telomere length and silencing protein 1 homolog. (289 aa) |
| | UBL5 | Ubiquitin-like protein 5. (73 aa) |
| | TSEN2 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (495 aa) |
| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | RNPC3 | RNA binding region (RNP1, RRM) containing 3. (515 aa) |
| | PRPF4 | U4/U6 small nuclear ribonucleoprotein Prp4 isoform X1. (521 aa) |
| | GCFC2 | GC-rich sequence DNA-binding factor 2 isoform 1. (784 aa) |
| | HTATSF1 | HIV-1 Tat specific factor 1. (684 aa) |
| | SNRPN | Small nuclear ribonucleoprotein-associated protein. (250 aa) |
| | TRA2B | Transformer 2 beta homolog. (288 aa) |
| | I3LBC7_PIG | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (110 aa) |
| | SNRNP27 | U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein. (155 aa) |
| | SNW1 | SNW domain-containing protein 1 isoform 2. (536 aa) |
| | FAM172A | Family with sequence similarity 172 member A. (416 aa) |
| | ZBTB8OS | Zinc finger and BTB domain containing 8 opposite strand. (167 aa) |
| | WT1 | Wilms tumor protein homolog; Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isofor [...] (523 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | CASC3 | CASC3 exon junction complex subunit. (633 aa) |
| | DHX8 | DEAH-box helicase 8. (1211 aa) |
| | EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component. (972 aa) |
| | TFIP11 | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (836 aa) |
| | SNRPD3 | Sm domain-containing protein. (281 aa) |
| | CWF19L1 | CWF19 like cell cycle control factor 1. (538 aa) |
| | SMU1 | Uncharacterized protein. (511 aa) |
| | RBM17 | RNA binding motif protein 17. (401 aa) |
| | RBM6 | RNA-binding protein 6 isoform 1. (1120 aa) |
| | PAXBP1 | PAX3 and PAX7 binding protein 1. (916 aa) |
| | GEMIN8 | Gem nuclear organelle associated protein 8. (239 aa) |
| | RBM41 | RNA binding motif protein 41. (442 aa) |
| | NCBP2L | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (152 aa) |
| | SF3B2 | Splicing factor 3B subunit 2 isoform X1. (895 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (803 aa) |
| | TRPT1 | tRNA phosphotransferase 1. (261 aa) |
| | PRPF19 | Pre-mRNA-processing factor 19. (504 aa) |
| | HNRNPM | Heterogeneous nuclear ribonucleoprotein M. (814 aa) |
| | WDR83 | WD repeat domain-containing protein 83. (311 aa) |
| | CCDC130 | Coiled-coil domain containing 130. (404 aa) |
| | FAM193B | FAM193_C domain-containing protein. (902 aa) |
| | LRRC51 | Uncharacterized protein. (193 aa) |
| | BUD13 | BUD13 homolog. (644 aa) |
| | ZPR1 | ZPR1 zinc finger. (455 aa) |
| | DCPS | m7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7- methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not h [...] (337 aa) |
| | RPUSD4 | RNA pseudouridylate synthase domain-containing protein 4. (376 aa) |
| | PUS7 | Pseudouridine synthase 7. (816 aa) |
| | HNRNPA3 | Heterogeneous nuclear ribonucleoprotein A3 isoform a. (379 aa) |
| | CWC22 | CWC22 spliceosome associated protein homolog. (903 aa) |
| | PPIL3 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa) |
| | CDK13 | Cyclin dependent kinase 13. (1513 aa) |
| | PPWD1 | Peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 1. (646 aa) |
| | SMN1 | Tudor domain-containing protein. (381 aa) |
| | SLU7 | Pre-mRNA-splicing factor SLU7 isoform X1. (586 aa) |
| | LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa) |
| | THOC3 | THO complex 3. (362 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (92 aa) |
| | SF3A3 | Splicing factor 3a subunit 3. (517 aa) |
| | LSM7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (150 aa) |
| | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor. (638 aa) |
| | RP9 | RP9 pre-mRNA splicing factor. (234 aa) |
| | USP39 | U4/U6.U5 tri-snRNP-associated protein 2 isoform 1. (565 aa) |
| | DNAJC8 | DnaJ heat shock protein family (Hsp40) member C8. (285 aa) |
| | ALYREF | Aly/REF export factor. (348 aa) |
| | TRA2A | Transformer 2 alpha homolog. (294 aa) |
| | XAB2 | XPA binding protein 2. (858 aa) |
| | CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (693 aa) |
| | CLASRP | CLK4 associating serine/arginine rich protein. (675 aa) |
| | SREK1IP1 | SREK1 interacting protein 1. (155 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (140 aa) |
| | YBX1 | Y-box binding protein 1. (419 aa) |
| | SRRM3 | Serine/arginine repetitive matrix 3. (746 aa) |
| | RBFOX1 | RNA binding fox-1 homolog 1. (577 aa) |
| | YJU2 | YJU2 splicing factor homolog. (377 aa) |
| | ZRSR2 | U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2. (479 aa) |
| | LSM8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (127 aa) |
| | SRPK3 | SRSF protein kinase 3; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity). (604 aa) |
| | TXNL4B | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa) |
| | DDX46 | DEAD-box helicase 46. (1033 aa) |
| | A0A5G2QMF2_PIG | RRM domain-containing protein. (318 aa) |
| | CELF6 | Uncharacterized protein. (610 aa) |
| | C1QBP | Mitochondrial complement component 1 Q subcomponent-binding protein. (281 aa) |
| | STRAP | Serine-threonine kinase receptor-associated protein. (350 aa) |
