(22 nodes) Negative regulation of epithelial to mesenchymal transition network (Sus scrofa)

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Your Input:
	FUZ	Fuzzy planar cell polarity protein. (418 aa)
	TRIM62	E3 ubiquitin-protein ligase TRIM62 isoform 1. (475 aa)
	DAB2IP	DAB2 interacting protein. (1196 aa)
	EFNA1	Ephrin-A1, secreted form; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial c [...] (205 aa)
	SFRP2	Uncharacterized protein. (294 aa)
	IL17RD	Interleukin-17 receptor D isoform a. (737 aa)
	PPP2CA	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa)
	EPHA4	EPH receptor A4. (986 aa)
	MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
	SFRP1	Secreted frizzled-related protein 1. (308 aa)
	FOXA1	Forkhead box A1. (468 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
	FOXA2	Hepatocyte nuclear factor 3-beta isoform 1. (463 aa)
	VASN	Vasorin isoform X2. (677 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (321 aa)
	SPRED1	Sprouty related EVH1 domain containing 1. (445 aa)
	SDHAF2	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (172 aa)
	HPN	Hepsin; Belongs to the peptidase S1 family. (449 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (315 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	NKX2-1	NK2 homeobox 1. (399 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAB2IP	SPRED1	ENSSSCP00000005920	ENSSSCP00000068826	DAB2 interacting protein.	Sprouty related EVH1 domain containing 1.	0.444
EFNA1	EPHA4	ENSSSCP00000006959	ENSSSCP00000017193	Ephrin-A1, secreted form; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial c [...]	EPH receptor A4.	0.987
EPHA4	EFNA1	ENSSSCP00000017193	ENSSSCP00000006959	EPH receptor A4.	Ephrin-A1, secreted form; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial c [...]	0.987
FOXA1	FOXA2	ENSSSCP00000042307	ENSSSCP00000035009	Forkhead box A1.	Hepatocyte nuclear factor 3-beta isoform 1.	0.401
FOXA1	GATA3	ENSSSCP00000042307	ENSSSCP00000041348	Forkhead box A1.	Trans-acting T-cell-specific transcription factor GATA-3.	0.979
FOXA1	NKX2-1	ENSSSCP00000042307	ENSSSCP00000054869	Forkhead box A1.	NK2 homeobox 1.	0.620
FOXA2	FOXA1	ENSSSCP00000035009	ENSSSCP00000042307	Hepatocyte nuclear factor 3-beta isoform 1.	Forkhead box A1.	0.401
FOXA2	GATA3	ENSSSCP00000035009	ENSSSCP00000041348	Hepatocyte nuclear factor 3-beta isoform 1.	Trans-acting T-cell-specific transcription factor GATA-3.	0.438
FOXA2	NKX2-1	ENSSSCP00000035009	ENSSSCP00000054869	Hepatocyte nuclear factor 3-beta isoform 1.	NK2 homeobox 1.	0.632
FOXA2	NOG	ENSSSCP00000035009	ENSSSCP00000053671	Hepatocyte nuclear factor 3-beta isoform 1.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.655
GATA3	FOXA1	ENSSSCP00000041348	ENSSSCP00000042307	Trans-acting T-cell-specific transcription factor GATA-3.	Forkhead box A1.	0.979
GATA3	FOXA2	ENSSSCP00000041348	ENSSSCP00000035009	Trans-acting T-cell-specific transcription factor GATA-3.	Hepatocyte nuclear factor 3-beta isoform 1.	0.438
NKX2-1	FOXA1	ENSSSCP00000054869	ENSSSCP00000042307	NK2 homeobox 1.	Forkhead box A1.	0.620
NKX2-1	FOXA2	ENSSSCP00000054869	ENSSSCP00000035009	NK2 homeobox 1.	Hepatocyte nuclear factor 3-beta isoform 1.	0.632
NOG	FOXA2	ENSSSCP00000053671	ENSSSCP00000035009	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Hepatocyte nuclear factor 3-beta isoform 1.	0.655
PPP2CA	SPRY2	ENSSSCP00000015208	ENSSSCP00000069477	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity).	Sprouty RTK signaling antagonist 2.	0.549
SPRED1	DAB2IP	ENSSSCP00000068826	ENSSSCP00000005920	Sprouty related EVH1 domain containing 1.	DAB2 interacting protein.	0.444
SPRY1	SPRY2	ENSSSCP00000067830	ENSSSCP00000069477	Sprouty RTK signaling antagonist 1.	Sprouty RTK signaling antagonist 2.	0.586
SPRY2	PPP2CA	ENSSSCP00000069477	ENSSSCP00000015208	Sprouty RTK signaling antagonist 2.	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity).	0.549
SPRY2	SPRY1	ENSSSCP00000069477	ENSSSCP00000067830	Sprouty RTK signaling antagonist 2.	Sprouty RTK signaling antagonist 1.	0.586