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| | C1QBP | Mitochondrial complement component 1 Q subcomponent-binding protein. (281 aa) |
| | MYF6 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). (249 aa) |
| | LIMK1 | LIM domain kinase 1. (681 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (931 aa) |
| | MAN2A1 | Alpha-mannosidase. (1164 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (835 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) |
| | F11R | Uncharacterized protein. (347 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | PLXND1 | Plexin D1. (1926 aa) |
| | MYADM | Myeloid associated differentiation marker. (391 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (924 aa) |
| | S1PR2 | Sphingosine 1-phosphate receptor 2. (351 aa) |
| | P4HB | Protein disulfide-isomerase. (623 aa) |
| | ROBO1 | Roundabout guidance receptor 1. (1687 aa) |
| | GOLGA4 | Golgin A4. (2241 aa) |
| | NTN1 | Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...] (651 aa) |
| | MYF5 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (253 aa) |
| | TGM2 | Transglutaminase 2. (696 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa) |
| | FERMT2 | Fermitin family member 2. (776 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (461 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | A0A5G2QF80_PIG | Uncharacterized protein. (287 aa) |
| | LAYN | C-type lectin domain-containing protein. (382 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (1011 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (489 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (670 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (332 aa) |
| | LOC110259156 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | NKX6-2 | Homeobox protein Nkx-6.2. (277 aa) |
| | A0A287BNW8_PIG | Uncharacterized protein. (99 aa) |
| | NEFL | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. (560 aa) |
| | ZFYVE27 | Zinc finger FYVE-type containing 27. (404 aa) |
| | NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (385 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CAPRIN1 | Cell cycle associated protein 1. (709 aa) |
| | IST1 | IST1 factor associated with ESCRT-III. (401 aa) |
| | SLC9B2 | Solute carrier family 9 member B2. (537 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) |
| | LIMS1 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa) |
| | DBN1 | Drebrin 1. (857 aa) |
| | NKX2-2 | Homeobox protein Nkx-2.2. (273 aa) |
| | ABL1 | Tyrosine-protein kinase. (1146 aa) |
| | OBSL1 | Obscurin-like protein 1 isoform X2. (1896 aa) |
| | IL1RAPL2 | Interleukin 1 receptor accessory protein like 2. (686 aa) |
| | LOC110255300 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (824 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (280 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (455 aa) |
| | SS18L1 | SS18L1 subunit of BAF chromatin remodeling complex. (416 aa) |
| | NIN | Ninein. (2136 aa) |
| | FAIM | Fas apoptotic inhibitory molecule. (207 aa) |
| | LRP2 | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4626 aa) |
| | BNC1 | Basonuclin 1. (987 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (433 aa) |
| | SERPINE2 | SERPIN domain-containing protein; Belongs to the serpin family. (378 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (596 aa) |
| | A0A287AXM5_PIG | PA14 domain-containing protein. (723 aa) |
| | FLNA | Filamin A. (2897 aa) |
| | BIN1 | Bridging integrator 1. (588 aa) |
| | MYOG | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] (215 aa) |
| | HES1 | Uncharacterized protein. (280 aa) |
| | CDH5 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] (782 aa) |
| | SHANK3 | SH3 and multiple ankyrin repeat domains 3. (1740 aa) |
| | ADIPOQ | C1q domain-containing protein. (332 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa) |
| | CDKL5 | Cyclin dependent kinase like 5. (999 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (260 aa) |
| | ZNF488 | Zinc finger protein 488. (323 aa) |
| | RNF112 | Ring finger protein 112. (628 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (967 aa) |
| | LOC110258579 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa) |
| | TRIOBP | TRIO and F-actin binding protein. (2043 aa) |
| | CASS4 | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). (810 aa) |
| | IL1B-2 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (244 aa) |
| | BAD | BCL2 associated agonist of cell death. (209 aa) |
| | ASPA | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). (380 aa) |
| | A0A287AB88_PIG | Uncharacterized protein. (124 aa) |
| | MYOC | Myocilin. (489 aa) |
| | NUMB | NUMB endocytic adaptor protein. (653 aa) |
| | PTN | Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups. Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone (By similarity). Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation (By similarity). Binds PTPRZ1, leading to neutralization of the negative char [...] (215 aa) |
| | IL34 | Interleukin 34. (243 aa) |
| | NPTN | Neuroplastin. (412 aa) |
| | PLXNA1 | Plexin A1. (1909 aa) |
| | LOC110258582 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (245 aa) |
| | FOXG1 | Forkhead box G1. (486 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (854 aa) |
| | PLXNC1 | Plexin C1. (1612 aa) |
| | BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) |
| | ISLR2 | Immunoglobulin superfamily containing leucine rich repeat 2. (806 aa) |
| | METRN | Uncharacterized protein. (393 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | LIF | Leukemia inhibitory factor isoform X1. (202 aa) |
| | BHLHB9 | Protein BHLHb9 Bhlhb9. (558 aa) |
| | SOX10 | Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). (542 aa) |
| | CARMIL1 | Capping protein regulator and myosin 1 linker 1. (1429 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa) |
| | SOX8 | SRY-box transcription factor 8. (460 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (548 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (385 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | LRP8 | LDL receptor related protein 8. (998 aa) |
| | ADD1 | Adducin 1. (786 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa) |
| | PAX6 | Paired box 6. (498 aa) |
| | ZNF335 | Zinc finger protein 335. (1354 aa) |
| | LOC110258125 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | OLIG2 | Oligodendrocyte transcription factor 2. (323 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (674 aa) |
| | JADE2 | Jade family PHD finger 2. (784 aa) |
| | LIMS2 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (357 aa) |
| | CTNNB1 | Catenin beta 1. (808 aa) |
| | SPEN | Spen family transcriptional repressor. (2726 aa) |
| | GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | PLXNA4 | Plexin-A4 isoform X1. (1893 aa) |
| | ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa) |
| | IL6ST | Interleukin 6 signal transducer. (938 aa) |
| | S100A10 | Protein S100-A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase. (97 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | CDC42 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa) |
| | SEMA4D | Semaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa) |
| | PLXNA3 | Plexin A3. (1871 aa) |
| | UFL1 | E3 UFM1-protein ligase 1. (792 aa) |
| | NR2E1 | Nuclear receptor subfamily 2 group E member 1. (385 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | CAPRIN2 | Caprin family member 2. (1069 aa) |
| | DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv1. (1012 aa) |
| | PROC | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. (523 aa) |
| | NUMBL | PID domain-containing protein. (1029 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa) |
| | SRRT | Serrate, RNA effector molecule. (875 aa) |
| | CDH4 | Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (914 aa) |
| | DISC1 | DISC1 scaffold protein. (819 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa) |
| | SEMA7A | Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (615 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | DMRTA2 | Doublesex-and mab-3-related transcription factor A2. (535 aa) |
| | ILK | Integrin linked kinase. (479 aa) |
| | PLXNA2 | Plexin A2. (1937 aa) |
| | SNW1 | SNW domain-containing protein 1 isoform 2. (536 aa) |
| | SHOX2 | Short stature homeobox 2. (321 aa) |
| | PDE3A | Phosphodiesterase. (1145 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | HAP1 | Huntingtin associated protein 1. (637 aa) |
| | GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (468 aa) |
| | UNC13D | Unc-13 homolog D. (1090 aa) |
| | METRNL | Meteorin like, glial cell differentiation regulator. (306 aa) |
| | GLI3 | GLI family zinc finger 3. (1586 aa) |
| | DBNL | Drebrin like. (429 aa) |
| | HOXA11 | Homeobox protein Hox-A11. (317 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa) |
| | STK25 | Serine/threonine kinase 25. (476 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | RELN | Reelin. (3458 aa) |
| | MAP6 | Microtubule associated protein 6. (820 aa) |
| | CDKL3 | Cyclin dependent kinase like 3. (617 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (133 aa) |
| | OTP | Orthopedia homeobox. (325 aa) |
| | CALR | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) |
| | MYOD1 | Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa) |
| | CLCF1 | Uncharacterized protein. (484 aa) |
| | PLXNB3 | Plexin B3. (1894 aa) |
| | DSCAM | DS cell adhesion molecule. (2008 aa) |
| | CHODL | Chondrolectin. (272 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (636 aa) |
| | TWF2 | Twinfilin actin binding protein 2. (500 aa) |
| | PLXNB1 | Plexin B1. (2133 aa) |
| | SHTN1 | Shootin 1. (631 aa) |
| | NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (638 aa) |
| | EGR2 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity); Belongs to the EGR C2H2-type zinc-finger protein family. (471 aa) |
| | ZNF365 | Zinc finger protein 365. (407 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | CUX2 | Homeobox protein cut-like. (1490 aa) |
| | DOCK5 | Dedicator of cytokinesis 5; Belongs to the DOCK family. (1867 aa) |
| | DMTN | Dematin actin binding protein. (405 aa) |
| | LIG4 | DNA ligase. (910 aa) |
| | DCT | L-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (519 aa) |
| | SLITRK1 | SLIT and NTRK-like protein 1. (695 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa) |
| | NKX6-1 | NK6 homeobox 1. (370 aa) |
| | GSX2 | GS homeobox 2. (304 aa) |
| | LOC110258578 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | IL1B2 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | CRABP2 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | PLAG1 | PLAG1 zinc finger. (499 aa) |
| | F1S1H9_PIG | PA14 domain-containing protein. (752 aa) |
| | TRIM32 | Tripartite motif containing 32. (652 aa) |
| | TESK1 | Dual specificity testis-specific protein kinase 1 isoform X1. (629 aa) |
| | PRKCH | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (374 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | KHDC3L | MOEP19 domain-containing protein. (142 aa) |
| | OPRM1 | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (418 aa) |
| | TIAM2 | T cell lymphoma invasion and metastasis 2. (1704 aa) |
| | LPAR3 | Lysophosphatidic acid receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa) |
| | EPHB2 | EPH receptor B2. (987 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2789 aa) |
| | ANKRD27 | Ankyrin repeat domain 27. (1059 aa) |
| | ISLR | Immunoglobulin superfamily containing leucine rich repeat. (436 aa) |
| | CIB1 | Calcium and integrin-binding protein 1 isoform b. (191 aa) |
| | F1RMG9_PIG | Uncharacterized protein. (298 aa) |
| | SRF | Serum response factor. (512 aa) |
| | CUL7 | Cullin-7 isoform X6; Belongs to the cullin family. (1691 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (829 aa) |
| | F1RW79_PIG | Uncharacterized protein. (708 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
