Your Input: | |
| | TEK | TEK receptor tyrosine kinase. (1147 aa) |
| | TESK1 | Dual specificity testis-specific protein kinase 1 isoform X1. (629 aa) |
| | ADAM15 | Disintegrin and metalloproteinase domain-containing protein 15 isoform 6 preproprotein. (866 aa) |
| | DLC1 | Rho GTPase-activating protein 7 isoform X1. (1528 aa) |
| | FERMT1 | Fermitin family member 1. (676 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa) |
| | COL26A1 | Collagen type XXVI alpha 1 chain. (439 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | AP1AR | Adaptor related protein complex 1 associated regulatory protein. (280 aa) |
| | DMTN | Dematin actin binding protein. (405 aa) |
| | DOCK5 | Dedicator of cytokinesis 5; Belongs to the DOCK family. (1867 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (436 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | NID1 | Nidogen 1. (1309 aa) |
| | PLAU | Urokinase-type plasminogen activator short chain A; Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. (442 aa) |
| | VCL | Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa) |
| | PEAK1 | Pseudopodium enriched atypical kinase 1. (1748 aa) |
| | CIB1 | Calcium and integrin-binding protein 1 isoform b. (191 aa) |
| | F1RMG9_PIG | Uncharacterized protein. (298 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (829 aa) |
| | F1RW79_PIG | Uncharacterized protein. (708 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | LDB1 | LID domain-containing protein. (411 aa) |
| | FBLN2 | Fibulin-2 isoform a. (1221 aa) |
| | HRG | Uncharacterized protein. (561 aa) |
| | BCL6 | B-cell lymphoma 6 protein isoform X1. (706 aa) |
| | MELTF | Melanotransferrin; Belongs to the transferrin family. (737 aa) |
| | ARHGAP6 | Rho GTPase activating protein 6. (705 aa) |
| | EGFL6 | EGF like domain multiple 6. (536 aa) |
| | CAMSAP3 | Calmodulin regulated spectrin associated protein family member 3. (1271 aa) |
| | CALR | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa) |
| | RELL2 | RELT like 2. (305 aa) |
| | SEMA3E | Semaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | EPHA1 | Ephrin type-A receptor 1. (982 aa) |
| | EGFLAM | EGF like, fibronectin type III and laminin G domains. (745 aa) |
| | CCL28 | C-C motif chemokine. (176 aa) |
| | TBCD | TFCD_C domain-containing protein. (1197 aa) |
| | UNC13D | Unc-13 homolog D. (1090 aa) |
| | JUP | Junction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...] (744 aa) |
| | NF1 | Neurofibromin 1. (2847 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (511 aa) |
| | ILK | Integrin linked kinase. (479 aa) |
| | VTN | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1340 aa) |
| | EPHA3 | Ephrin type-A receptor 3 isoform X1. (984 aa) |
| | VIT | Vitrin. (656 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | HOXA7 | Homeobox A7. (234 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (766 aa) |
| | PHLDB2 | Pleckstrin homology like domain family B member 2. (1253 aa) |
| | SERPINE1 | Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa) |
| | RIN2 | Ras and Rab interactor 2. (517 aa) |
| | ECM2 | Extracellular matrix protein 2. (696 aa) |
| | JAK2 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1131 aa) |
| | APOD | Apolipoprotein D. (228 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1360 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | CDC42 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (786 aa) |
| | S100A10 | Protein S100-A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase. (97 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | DDR1 | Tyrosine-protein kinase receptor. (1005 aa) |
| | LIMS2 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (357 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (674 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa) |
| | COL16A1 | Collagen alpha-1(XVI) chain isoform X2. (1624 aa) |
| | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (439 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (270 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (385 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | CARMIL1 | Capping protein regulator and myosin 1 linker 1. (1429 aa) |
| | PLET1 | Placenta-expressed transcript 1 protein; Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle (By similarity). (202 aa) |
| | CCL21 | Putative CCL21 chemokine. (134 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (731 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (274 aa) |
| | CCDC80 | Coiled-coil domain containing 80. (1016 aa) |
| | GCNT2 | Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa) |
| | ACTN4 | Actinin alpha 4. (1160 aa) |
| | MYOC | Myocilin. (489 aa) |
| | ACTG1 | Actin gamma 1. (381 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa) |
| | FOXF1 | Forkhead box protein F1. (423 aa) |
| | CASS4 | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). (810 aa) |
| | RRAS | RAS related. (218 aa) |
| | MACF1 | Microtubule actin crosslinking factor 1. (4482 aa) |
| | TRIOBP | TRIO and F-actin binding protein. (2043 aa) |
| | FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (819 aa) |
| | AGR2 | Anterior gradient 2, protein disulphide isomerase family member. (206 aa) |
| | LIMCH1 | LIM and calponin homology domains 1. (1469 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (554 aa) |
| | RHOA | Transforming protein RhoA isoform 1. (193 aa) |
| | SLK | STE20 like kinase. (1237 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (414 aa) |
| | SPOCK2 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (424 aa) |
| | FLNA | Filamin A. (2897 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) |
| | ARL2 | ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family. (211 aa) |
| | THY1 | Thy-1 cell surface antigen. (165 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PTPRA | Protein tyrosine phosphatase receptor type A. (850 aa) |
| | FMN1 | Formin 1. (1195 aa) |
| | ABL1 | Tyrosine-protein kinase. (1146 aa) |
| | SKAP1 | Src kinase-associated phosphoprotein 1. (367 aa) |
| | VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (451 aa) |
| | LIMS1 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa) |
| | KANK1 | KN motif and ankyrin repeat domains 1. (1331 aa) |
| | CORO2A | Coronin; Belongs to the WD repeat coronin family. (505 aa) |
| | EFEMP2 | EGF containing fibulin extracellular matrix protein 2. (498 aa) |
| | EDIL3 | EGF like repeats and discoidin domains 3. (477 aa) |
| | NEXMIF | Neurite extension and migration factor. (1514 aa) |
| | AJAP1 | Adherens junctions associated protein 1. (527 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | PLEKHA2 | Pleckstrin homology domain containing A2. (424 aa) |
| | CSF1 | Colony stimulating factor 1. (656 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa) |
| | CDH13 | Uncharacterized protein. (771 aa) |
| | RASA1 | RAS p21 protein activator 1. (1040 aa) |
| | RSU1 | Ras suppressor protein 1. (281 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (1292 aa) |
| | RAC1 | Rac family small GTPase 1. (186 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. (364 aa) |
| | ABI3BP | ABI family member 3 binding protein. (1668 aa) |
| | A0A5G2QF80_PIG | Uncharacterized protein. (287 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | FERMT2 | Fermitin family member 2. (776 aa) |
| | C1QBP | Mitochondrial complement component 1 Q subcomponent-binding protein. (281 aa) |
| | MYF5 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (253 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1477 aa) |
| | CCN1 | Cellular communication network factor 1. (382 aa) |
| | EMID1 | EMI domain containing 1. (509 aa) |
| | BST1 | Bone marrow stromal cell antigen 1. (302 aa) |
| | ANGPT2 | Angiopoietin-2; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell- matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). (495 aa) |
| | UTRN | Uncharacterized protein. (3433 aa) |
| | DMD | Dystrophin; Anchors the extracellular matrix to the cytoskeleton via F- actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. (3679 aa) |
| | P4HB | Protein disulfide-isomerase. (623 aa) |
| | CCL25 | C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (924 aa) |
| | MYADM | Myeloid associated differentiation marker. (391 aa) |
| | SPRY4 | Sprouty RTK signaling antagonist 4. (325 aa) |
| | RAC2 | Rac family small GTPase 2. (217 aa) |
| | COL8A1 | Collagen type VIII alpha 1 chain. (759 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (925 aa) |
| | STK4 | Serine/threonine kinase 4. (502 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (835 aa) |
| | TSC1 | TSC complex subunit 1. (1166 aa) |
| | PDPN | Uncharacterized protein. (159 aa) |
| | ONECUT2 | One cut domain family member. (694 aa) |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | THBS1 | Uncharacterized protein. (1170 aa) |
| | CORO2B | Coronin; Belongs to the WD repeat coronin family. (554 aa) |
