STRINGSTRING
SPINK7 SPINK7 AMBP AMBP AGT AGT SRC SRC PAX2 PAX2 ANXA2 ANXA2 MT3 MT3 LOC110261633 LOC110261633 CDKN2D CDKN2D SERPINA4 SERPINA4 SPOCK1 SPOCK1 SERPINH1 SERPINH1 WFDC2 WFDC2 RNF34 RNF34 ITIH4 ITIH4 LOC110261265 LOC110261265 CSTA CSTA WFIKKN1 WFIKKN1 PTGS2 PTGS2 TMED10 TMED10 GAPDH GAPDH SERPINB12 SERPINB12 LOC106504547 LOC106504547 TIMP3 TIMP3 CD109 CD109 APLP2 APLP2 SLPI SLPI XIAP XIAP WFDC11 WFDC11 SPINK6 SPINK6 BST2 BST2 SERPINA5 SERPINA5 NLE1 NLE1 PIH1D1 PIH1D1 BIRC5 BIRC5 WFDC10AL WFDC10AL SPINK14 SPINK14 C5 C5 RPS6KA1 RPS6KA1 A0A287AKL9_PIG A0A287AKL9_PIG LOC100621494 LOC100621494 SERPINB13 SERPINB13 NR4A1 NR4A1 KIF12 KIF12 SIAH2 SIAH2 CRYAB CRYAB BIN1 BIN1 SPAI-2 SPAI-2 TFPI TFPI IFI6 IFI6 A0A287AXL0_PIG A0A287AXL0_PIG GAS6 GAS6 PTI PTI SERPINE2 SERPINE2 SERPINF1 SERPINF1 MMP9 MMP9 COL6A3 COL6A3 FAM124B FAM124B CST9L CST9L UBE2Z UBE2Z LTF LTF SERPINE1 SERPINE1 UPTI UPTI LXN LXN WFDC10A WFDC10A SERPINB11 SERPINB11 PSMF1 PSMF1 LOC100524679 LOC100524679 PCSK1N PCSK1N CSTB CSTB VTN VTN USP14 USP14 DPEP1 DPEP1 LOC396905 LOC396905 WFIKKN2 WFIKKN2 PTTG1 PTTG1 WAP WAP VIL1 VIL1 HGF HGF TFPI2 TFPI2 PICALM PICALM SPINK9 SPINK9 FNIP1 FNIP1 CAST CAST C3 C3 CD44 CD44 SERPING1 SERPING1 PRDX5 PRDX5 CST6 CST6 SERPINA7 SERPINA7 TIMP1 TIMP1 DDX3X DDX3X APP APP PAK2 PAK2 HRG HRG FETUB FETUB SERPINI2 SERPINI2 LOC100736951 LOC100736951 ITIH5 ITIH5 ITIH2 ITIH2 SPINK4 SPINK4 UCHL5 UCHL5 PRDX3 PRDX3 SERPIND1 SERPIND1 SPOCK3 SPOCK3 SH3RF1 SH3RF1 PCID2 PCID2 SERPINE3 SERPINE3 CSN2 CSN2 SFRP2 SFRP2 BIRC6 BIRC6 CRIM1 CRIM1 INTS1 INTS1 WFDC3 WFDC3 WFDC9 WFDC9 WFDC8 WFDC8 WFDC5 WFDC5 AVP AVP CST7 CST7 CST8 CST8 LOC100515765 LOC100515765 CST11 CST11 CSTL1 CSTL1 CRB2 CRB2 SERPINB5 SERPINB5 SERPINB7 SERPINB7 SERPINB2 SERPINB2 SERPINB10 SERPINB10 SERPINB8 SERPINB8 THBS1 THBS1 MICAL1 MICAL1 PARK7 PARK7 LOC396684 LOC396684 LOC106504545 LOC106504545 UABP-2 UABP-2 SERPINA11 SERPINA11 SERPINA12 SERPINA12 SERPINA1 SERPINA1 SERPINA6 SERPINA6 PAPLN PAPLN SERPINB1 SERPINB1 CD27 CD27 A2ML1 A2ML1 A2M A2M BIRC3 BIRC3 TIMP4 TIMP4 SERPINF2 SERPINF2 A0A287B8V2_PIG A0A287B8V2_PIG PLAUR PLAUR LOC100512873 LOC100512873 UBE2O UBE2O A0A287B396_PIG A0A287B396_PIG ITIH1 ITIH1 NOL3 NOL3 LAMTOR5 LAMTOR5 RFFL RFFL CST3 CST3 AHSG AHSG SPINT1 SPINT1 LOC100153783 LOC100153783 PI3 PI3 SPINK2 SPINK2 FURIN FURIN SPINT2 SPINT2 COL28A1 COL28A1 BIRC7 BIRC7 SERPINB6 SERPINB6 SERPINA3-2 SERPINA3-2 NGF NGF LRP11 LRP11 PZP PZP SERPINB9 SERPINB9 SPINK1 SPINK1 SORL1 SORL1 ITIH3 ITIH3 A0A287BQB3_PIG A0A287BQB3_PIG FAM124A FAM124A TNFAIP8 TNFAIP8 ANXA8 ANXA8 AQP1 AQP1 LOC100517145 LOC100517145 C4A C4A SERPINI1 SERPINI1 SPINK13 SPINK13 LOC100739218 LOC100739218 SPINK5 SPINK5 USP47 USP47 RECK RECK ROCK1 ROCK1 RARRES1 RARRES1 CSNK2A1 CSNK2A1 LOC100158011 LOC100158011 TNFSF14 TNFSF14 TIMP2 TIMP2 SERPINC1 SERPINC1 SPINK8 SPINK8 LOC100516119 LOC100516119 KNG1 KNG1 RPS6KA3 RPS6KA3 A0A5G2R112_PIG A0A5G2R112_PIG BIRC7-2 BIRC7-2 A0A5G2RMR0_PIG A0A5G2RMR0_PIG A0A5G2RGT7_PIG A0A5G2RGT7_PIG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SPINK7Serine peptidase inhibitor, Kazal type 7 (putative). (85 aa)
AMBPInter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. (364 aa)
AGTAngiotensinogen; Belongs to the serpin family. (482 aa)
SRCTyrosine-protein kinase. (559 aa)
PAX2Paired box 2. (416 aa)
ANXA2Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (414 aa)
MT3Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa)
LOC110261633SERPIN domain-containing protein; Belongs to the serpin family. (388 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
SERPINA4Serpin family A member 4; Belongs to the serpin family. (371 aa)
SPOCK1SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (439 aa)
SERPINH1SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)
WFDC2WAP four-disulfide core domain protein 2; Broad range protease inhibitor. (123 aa)
RNF34E3 ubiquitin-protein ligase RNF34 isoform 2. (383 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain H4; Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. (976 aa)
LOC110261265NTR domain-containing protein. (239 aa)
CSTACystatin-A8; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (103 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
TMED10Transmembrane emp24 domain-containing protein 10. (219 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (398 aa)
SERPINB12Serpin family B member 12; Belongs to the serpin family. (425 aa)
LOC106504547SERPIN domain-containing protein; Belongs to the serpin family. (445 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
CD109CD109 antigen isoform 1 preproprotein. (1449 aa)
APLP2Amyloid beta precursor like protein 2. (770 aa)
SLPIAntileukoproteinase; Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance t [...] (170 aa)
XIAPX-linked inhibitor of apoptosis. (514 aa)
WFDC11WAP four-disulfide core domain 11. (90 aa)
SPINK6Serine peptidase inhibitor, Kazal type 6. (80 aa)
BST2Uncharacterized protein. (177 aa)
SERPINA5Plasma serine protease inhibitor preproprotein; Belongs to the serpin family. (408 aa)
NLE1Notchless homolog 1. (487 aa)
PIH1D1PIH1 domain containing 1. (289 aa)
BIRC5Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] (142 aa)
WFDC10ALWAP four-disulfide core domain protein 10A. (108 aa)
SPINK14Serine peptidase inhibitor, Kazal type 14 (putative). (98 aa)
C5Complement C5a anaphylatoxin; Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. (1677 aa)
RPS6KA1Ribosomal protein S6 kinase. (856 aa)
A0A287AKL9_PIGWAP four-disulfide core domain protein 15B. (79 aa)
LOC100621494SERPIN domain-containing protein; Belongs to the serpin family. (407 aa)
SERPINB13Serpin family B member 13; Belongs to the serpin family. (390 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1 isoform 2. (598 aa)
KIF12Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (651 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (237 aa)
BIN1Bridging integrator 1. (588 aa)
SPAI-2Sodium/potassium ATPase inhibitor SPAI-2; Inhibits Na(+),K(+) ATPase by the competitive mode against Na(+). (187 aa)
TFPITissue factor pathway inhibitor. (303 aa)
IFI6Interferon alpha inducible protein 6. (171 aa)
A0A287AXL0_PIGUncharacterized protein. (502 aa)
GAS6Uncharacterized protein. (682 aa)
PTIBPTI/Kunitz inhibitor domain-containing protein. (247 aa)
SERPINE2SERPIN domain-containing protein; Belongs to the serpin family. (378 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (433 aa)
MMP9Matrix metalloproteinase-9. (708 aa)
COL6A3Collagen type VI alpha 3 chain. (2911 aa)
FAM124BFamily with sequence similarity 124 member B. (454 aa)
CST9LCystatin-9-like. (149 aa)
UBE2ZUbiquitin-conjugating enzyme E2 Z. (356 aa)
LTFLactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa)
SERPINE1Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa)
UPTIUterine plasmin/trypsin inhibitor; Inhibitor of plasmin and trypsin. Also has a weak affinity for chymotrypsin. Could serve to neutralize the activities of one or more serine proteinases generated by the proliferating trophoblast during the formation of the noninvasive placenta. (103 aa)
LXNLatexin. (222 aa)
WFDC10AWAP four-disulfide core domain 10A. (78 aa)
SERPINB11Serpin family B member 11 (gene/pseudogene); Belongs to the serpin family. (392 aa)
PSMF1Uncharacterized protein. (351 aa)
LOC100524679Uncharacterized protein. (1397 aa)
PCSK1NProprotein convertase subtilisin/kexin type 1 inhibitor. (259 aa)
CSTBCystatin-B; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (98 aa)
VTNVitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (505 aa)
DPEP1Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (409 aa)
LOC396905Sperm-associated acrosin inhibitor; Inhibits acrosin. (162 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (580 aa)
PTTG1Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] (202 aa)
WAPWhey acidic protein; Could be a protease inhibitor. May play an important role in mammary gland development and tissue remodeling. (132 aa)
VIL1Villin-1; Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the inte [...] (826 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa)
TFPI2Tissue factor pathway inhibitor. (232 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (700 aa)
SPINK9Serine peptidase inhibitor, Kazal type 9. (84 aa)
FNIP1Folliculin interacting protein 1. (1061 aa)
CASTCalpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue; Belongs to the protease inhibitor I27 (calpastatin) family. (835 aa)
C3Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. (1661 aa)
CD44CD44 molecule (Indian blood group). (767 aa)
SERPING1Plasma protease C1 inhibitor isoform X1; Belongs to the serpin family. (491 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (170 aa)
CST6Cystatin E/M; Belongs to the cystatin family. (149 aa)
SERPINA7Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. (420 aa)
TIMP1Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (756 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
HRGUncharacterized protein. (561 aa)
FETUBFetuin-B isoform 1. (377 aa)
SERPINI2Serpin family I member 2; Belongs to the serpin family. (405 aa)
LOC100736951Uncharacterized protein. (177 aa)
ITIH5Inter-alpha-trypsin inhibitor heavy chain 5. (944 aa)
ITIH2Inter-alpha-trypsin inhibitor heavy chain H2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. (923 aa)
SPINK4Serine protease inhibitor Kazal-type 4; Inhibits the glucose-induced insulin secretion from perfused pancreas; also plays a role in the immune system. Does not inhibit trypsin. (86 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase isozyme L5; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity). (327 aa)
PRDX3Thioredoxin domain-containing protein. (261 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (517 aa)
SPOCK3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (436 aa)
SH3RF1E3 ubiquitin-protein ligase SH3RF1 isoform X1. (849 aa)
PCID2PCI domain-containing protein 2 isoform X1. (399 aa)
SERPINE3Serpin family E member 3; Belongs to the serpin family. (408 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (231 aa)
SFRP2Uncharacterized protein. (294 aa)
BIRC6Baculoviral IAP repeat containing 6. (4843 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1031 aa)
INTS1Integrator complex subunit 1. (2191 aa)
WFDC3WAP domain-containing protein. (94 aa)
WFDC9WAP four-disulfide core domain 9. (88 aa)
WFDC8WAP four-disulfide core domain 8. (252 aa)
WFDC5WAP four-disulfide core domain 5. (166 aa)
AVPVasopressin-neurophysin 2-copeptin. (217 aa)
CST7Cystatin domain-containing protein. (146 aa)
CST8Cystatin domain-containing protein. (274 aa)
LOC100515765Cystatin domain-containing protein. (128 aa)
CST11Cystatin 11. (137 aa)
CSTL1Cystatin like 1. (137 aa)
CRB2Crumbs cell polarity complex component 2. (1283 aa)
SERPINB5Serpin family B member 5; Belongs to the serpin family. (375 aa)
SERPINB7Serpin family B member 7; Belongs to the serpin family. (380 aa)
SERPINB2Plasminogen activator inhibitor 2; Belongs to the serpin family. (440 aa)
SERPINB10SERPIN domain-containing protein; Belongs to the serpin family. (397 aa)
SERPINB8Serpin family B member 8; Belongs to the serpin family. (374 aa)
THBS1Uncharacterized protein. (1170 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1122 aa)
PARK7DJ-1 protein. (189 aa)
LOC396684SERPIN domain-containing protein; Belongs to the serpin family. (411 aa)
LOC106504545SERPIN domain-containing protein; Belongs to the serpin family. (417 aa)
UABP-2Uteroferrin-associated basic protein 2. (420 aa)
SERPINA11Serpin family A member 11; Belongs to the serpin family. (514 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (414 aa)
SERPINA1Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity). (420 aa)
SERPINA6Corticosteroid-binding globulin; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. (434 aa)
PAPLNPapilin, proteoglycan like sulfated glycoprotein. (961 aa)
SERPINB1Leukocyte elastase inhibitor; Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Acts also as a [...] (413 aa)
CD27CD27. (249 aa)
A2ML1Alpha-2-macroglobulin like 1. (1457 aa)
A2MAlpha-2-macroglobulin. (1504 aa)
BIRC3Baculoviral IAP repeat containing 3. (603 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
SERPINF2Alpha-2-antiplasmin isoform X2; Belongs to the serpin family. (563 aa)
A0A287B8V2_PIGWAP domain-containing protein. (73 aa)
PLAURPlasminogen activator, urokinase receptor. (330 aa)
LOC100512873Antileukoproteinase. (157 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1296 aa)
A0A287B396_PIGWAP domain-containing protein. (73 aa)
ITIH1Inter-alpha-trypsin inhibitor heavy chain H1; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. (927 aa)
NOL3Nucleolar protein 3. (237 aa)
LAMTOR5Ragulator complex protein LAMTOR5; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assem [...] (229 aa)
RFFLUncharacterized protein. (799 aa)
CST3Cystatin C; Belongs to the cystatin family. (146 aa)
AHSGAlpha-2-HS-glycoprotein. (394 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
LOC100153783Ovalbumin isoform X1; Belongs to the serpin family. (385 aa)
PI3Elafin; Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis (By similarity). (167 aa)
SPINK2Serine protease inhibitor Kazal-type 2 isoform 1. (85 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (252 aa)
COL28A1Collagen type XXVIII alpha 1 chain. (1236 aa)
BIRC7RING-type domain-containing protein. (151 aa)
SERPINB6SERPIN domain-containing protein; Belongs to the serpin family. (399 aa)
SERPINA3-2SERPIN domain-containing protein; Belongs to the serpin family. (473 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (385 aa)
LRP11LDL receptor related protein 11. (517 aa)
PZPUncharacterized protein. (1416 aa)
SERPINB9SERPIN domain-containing protein; Belongs to the serpin family. (495 aa)
SPINK1Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). (79 aa)
SORL1Sortilin related receptor 1. (2213 aa)
ITIH3Inter-alpha-trypsin inhibitor heavy chain 3. (907 aa)
A0A287BQB3_PIGUncharacterized protein. (149 aa)
FAM124AFamily with sequence similarity 124 member A. (591 aa)
TNFAIP8TNF alpha induced protein 8. (212 aa)
ANXA8Annexin. (354 aa)
AQP1Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (280 aa)
LOC100517145Uncharacterized protein. (1670 aa)
C4AUncharacterized protein. (1758 aa)
SERPINI1Serpin family I member 1; Belongs to the serpin family. (502 aa)
SPINK13Kazal-like domain-containing protein. (173 aa)
LOC100739218Uncharacterized protein. (143 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1023 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1356 aa)
RECKReversion-inducing cysteine-rich protein with Kazal motifs isoform 1. (971 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
RARRES1Retinoic acid receptor responder protein 1 isoform X1. (290 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (398 aa)
LOC100158011BPTI/Kunitz inhibitor domain-containing protein. (128 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform 1. (241 aa)
TIMP2Uncharacterized protein. (257 aa)
SERPINC1SERPIN domain-containing protein; Belongs to the serpin family. (431 aa)
SPINK8Serine peptidase inhibitor, Kazal type 8 (putative). (95 aa)
LOC100516119Cystatin domain-containing protein. (186 aa)
KNG1Kininogen 1. (630 aa)
RPS6KA3Ribosomal protein S6 kinase. (744 aa)
A0A5G2R112_PIGBPTI/Kunitz inhibitor domain-containing protein. (84 aa)
BIRC7-2Uncharacterized protein. (428 aa)
A0A5G2RMR0_PIGWAP domain-containing protein. (128 aa)
A0A5G2RGT7_PIGUncharacterized protein. (147 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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