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HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (525 aa) | ||||
IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (230 aa) | ||||
RGL2 | Uncharacterized protein. (802 aa) | ||||
PPARD | Peroxisome proliferator-activated receptor delta. (441 aa) | ||||
SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (414 aa) | ||||
FGR | Tyrosine-protein kinase. (537 aa) | ||||
ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (797 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1147 aa) | ||||
DAB2IP | DAB2 interacting protein. (1196 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (795 aa) | ||||
HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools; Belongs to the HAX1 family. (284 aa) | ||||
PPP1R16B | Protein phosphatase 1 regulatory inhibitor subunit 16B isoform X1. (568 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (286 aa) | ||||
NCF1 | Uncharacterized protein. (378 aa) | ||||
ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa) | ||||
OSM | Oncostatin M. (234 aa) | ||||
PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1. (296 aa) | ||||
SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa) | ||||
PLXNB1 | Plexin B1. (2133 aa) | ||||
F2 | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). (623 aa) | ||||
CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (550 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1382 aa) | ||||
F2RL1 | Proteinase-activated receptor 2 preproprotein. (397 aa) | ||||
PDGFD | Platelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (387 aa) | ||||
SEMA3E | Semaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa) | ||||
HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) | ||||
RELN | Reelin. (3458 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1201 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) | ||||
FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) | ||||
PRR5 | Proline rich 5. (386 aa) | ||||
PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (396 aa) | ||||
GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1194 aa) | ||||
NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (470 aa) | ||||
JAK2 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1131 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1360 aa) | ||||
SEMA4D | Semaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa) | ||||
AGT | Angiotensinogen; Belongs to the serpin family. (482 aa) | ||||
UNC5B | Unc-5 netrin receptor B. (934 aa) | ||||
CBL | Cbl proto-oncogene. (914 aa) | ||||
F2R | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (427 aa) | ||||
TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (612 aa) | ||||
TREM2 | Ig-like domain-containing protein. (248 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
STAMBP | STAM-binding protein isoform 1. (494 aa) | ||||
UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa) | ||||
MYOC | Myocilin. (489 aa) | ||||
PDGFB | Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa) | ||||
FBXL2 | F-box and leucine rich repeat protein 2. (476 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) | ||||
CRNN | Cornulin. (659 aa) | ||||
PRR5L | Proline rich 5 like. (473 aa) | ||||
SERPINE2 | SERPIN domain-containing protein; Belongs to the serpin family. (378 aa) | ||||
CEP55 | Centrosomal protein 55. (480 aa) | ||||
HCST | Hematopoietic cell signal transducer; Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain- related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST trigg [...] (281 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) | ||||
NEDD4 | E3 ubiquitin-protein ligase NEDD4 isoform 3. (1323 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) | ||||
NKX3-1 | Homeobox protein Nkx-3.1 isoform 1. (247 aa) | ||||
DIPK2A | Divergent protein kinase domain 2A. (430 aa) | ||||
MYDGF | Myeloid derived growth factor. (247 aa) | ||||
MAZ | MYC associated zinc finger protein. (494 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1302 aa) | ||||
PIK3AP1 | Phosphoinositide-3-kinase adaptor protein 1. (905 aa) | ||||
CSF3 | Granulocyte colony-stimulating factor; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes (By similarity); Belongs to the IL-6 superfamily. (204 aa) | ||||
SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (365 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1205 aa) | ||||
CD28 | IGv domain-containing protein. (222 aa) | ||||
NTRK3 | NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. (864 aa) | ||||
SELP | Uncharacterized protein. (671 aa) |