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| | GSTO1 | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. (241 aa) |
| | F1S5N8_PIG | Uncharacterized protein; Belongs to the GST superfamily. (217 aa) |
| | A0A5S6G633_PIG | Alpha-S1-casein. (180 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (151 aa) |
| | PTGES | Microsomal prostaglandin E synthase-1. (153 aa) |
| | SELENOS | Selenoprotein S; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination (By similarity). (190 aa) |
| | DUOX2 | Dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. (1539 aa) |
| | TXNL1 | Thioredoxin like 1. (394 aa) |
| | PARK7 | DJ-1 protein. (189 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (292 aa) |
| | GPX2 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa) |
| | GPX5 | Epididymal secretory glutathione peroxidase; May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. (219 aa) |
| | GPX6 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (220 aa) |
| | ALOX5AP | Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family. (161 aa) |
| | PRDX3 | Thioredoxin domain-containing protein. (261 aa) |
| | PRDX5 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (170 aa) |
| | F1RMF5_PIG | Glutaredoxin domain-containing protein. (106 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (550 aa) |
| | GSR | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa) |
| | EPX | Eosinophil peroxidase heavy chain; Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils; Belongs to the peroxidase family. XPO subfamily. (705 aa) |
| | PXDN | Peroxidasin. (1529 aa) |
| | NXN | Nucleoredoxin. (439 aa) |
| | LTC4S | Leukotriene C4 synthase. (146 aa) |
| | PRXL2B | Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha). (202 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (155 aa) |
| | GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (158 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (303 aa) |
| | SRXN1 | Sulfiredoxin. (136 aa) |
| | AMBP | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. (364 aa) |
| | S100A9 | EF-hand domain-containing protein; Belongs to the S-100 family. (222 aa) |
| | S100A8 | Protein S100; Belongs to the S-100 family. (89 aa) |
| | DUOX1 | Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. (1552 aa) |
| | MPO | Myeloperoxidase. (731 aa) |
| | NXNL2 | Nucleoredoxin like 2. (156 aa) |
| | PRDX1 | Peroxiredoxin-1. (224 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | TXNDC17 | Thioredoxin domain containing 17. (123 aa) |
| | GPX7 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (317 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the MAPEG family. (155 aa) |
| | PRDX2 | Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2); Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (237 aa) |
| | BTBD6 | BTB domain containing 6. (538 aa) |
| | C12H17orf100 | Uncharacterized protein. (160 aa) |
| | A0A287AB76_PIG | Glutaredoxin domain-containing protein. (106 aa) |
| | GPX1 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (205 aa) |
| | HP | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] (354 aa) |
| | GPX3 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa) |
| | SELENOW | Selenoprotein W; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity). (90 aa) |
| | PTGS1 | Prostaglandin G/H synthase 1 isoform 1. (600 aa) |
| | A0A287ANJ1_PIG | Glutaredoxin domain-containing protein. (106 aa) |
| | SOD2 | Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (485 aa) |
| | GPX4 | Phospholipid hydroperoxide glutathione peroxidase; Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins. Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide. Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation (By similarity). Required to prevent cells from ferroptosis, a non- apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (By similarity). The presence of s [...] (197 aa) |
| | A0A287ASH7_PIG | DSBA domain-containing protein. (150 aa) |
| | NXNL1 | Nucleoredoxin like 1. (214 aa) |
| | APOM | Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1- phosphate, myristic acid, palmitic acid and stearic acid, retinol, all- trans-retinoic acid and 9-cis-retinoic acid (By similarity). (200 aa) |
| | A0A287AWM8_PIG | Glutaredoxin domain-containing protein. (106 aa) |
| | RTTN | Rotatin. (2231 aa) |
| | UBIAD1 | UbiA prenyltransferase domain-containing protein 1 isoform 1. (338 aa) |
| | TMEM221 | Uncharacterized protein. (291 aa) |
| | PRXL2A | Peroxiredoxin like 2A. (229 aa) |
| | PRDX6 | Peroxiredoxin-6; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role [...] (224 aa) |
| | CCS | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. (307 aa) |
| | SELENOT | Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (137 aa) |
| | TP53INP1 | Tumor protein p53-inducible nuclear protein 1 isoform X1. (239 aa) |
| | PRXL2C | Thioredoxin-like protein AAED1. (228 aa) |
| | APOA4 | Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. (392 aa) |
| | TXNRD2 | Uncharacterized protein. (606 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (146 aa) |
| | GLRX | Glutaredoxin-1; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins; Belongs to the glutaredoxin family. (106 aa) |
| | PRDX4 | Peroxiredoxin 4. (276 aa) |
| | TXNRD3 | Thioredoxin reductase 3; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (622 aa) |
| | GSTK1 | DSBA domain-containing protein. (243 aa) |
| | TXNRD1 | Thioredoxin reductase 1, cytoplasmic. (651 aa) |
| | SESN2 | Sestrin 2. (471 aa) |
| | LPO | Lactoperoxidase isoform 1 preproprotein. (712 aa) |
| | CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (259 aa) |
| | YIPF5 | Protein YIPF. (257 aa) |
| | A0A5G2RJL8_PIG | Glutaredoxin domain-containing protein. (104 aa) |
| | MFSD11 | Major facilitator superfamily domain containing 11. (491 aa) |
| | A0A5G2RGT7_PIG | Uncharacterized protein. (147 aa) |
| | TPO | Thyroid peroxidase; Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). Belongs to the peroxidase family. XPO subfamily. (911 aa) |
| | GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa) |
