STRINGSTRING
ULK1 ULK1 ATG7 ATG7 ATG13 ATG13 ATG4B ATG4B ATG2B ATG2B ATG2A ATG2A RB1CC1 RB1CC1 ATG16L1 ATG16L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ULK1Unc-51 like autophagy activating kinase 1. (1176 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (710 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (402 aa)
ATG2BAutophagy related 2B. (2077 aa)
ATG2AAutophagy related 2A. (1929 aa)
RB1CC1RB1 inducible coiled-coil 1. (1608 aa)
ATG16L1Autophagy-related protein 16-1 isoform X1. (623 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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