STRINGSTRING
IVD IVD SDHC SDHC LBR LBR ACOXL ACOXL ACOX2 ACOX2 PTGR2 PTGR2 TECRL TECRL DUS1L DUS1L ACADS ACADS ZADH2 ZADH2 PTGR1 PTGR1 CRAT CRAT ACOX1 ACOX1 ACAD9 ACAD9 SDHA SDHA BLVRB BLVRB DUS4L DUS4L DHCR7 DHCR7 BDH2 BDH2 FASN FASN PECR PECR LOC100525350 LOC100525350 RSAD1 RSAD1 SRD5A1 SRD5A1 AKR1D1 AKR1D1 TBXAS1 TBXAS1 ACADL ACADL DUS3L DUS3L TM7SF2 TM7SF2 CPOX CPOX ACAD11 ACAD11 ACAA1 ACAA1 ACAD10 ACAD10 SRD5A2 SRD5A2 RETSAT RETSAT DPYD DPYD PTGES2 PTGES2 BAX BAX ACADSB ACADSB PPOX PPOX GCDH GCDH TECR TECR BLVRA BLVRA DECR2 DECR2 ACOX3 ACOX3 DHODH DHODH A0A5G2QSB6_PIG A0A5G2QSB6_PIG ACADM ACADM ACADVL ACADVL DECR1 DECR1 SDHB SDHB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IVDUncharacterized protein. (568 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the cytochrome b560 family. (176 aa)
LBRLamin-B receptor. (626 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (708 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
PTGR2Prostaglandin reductase 2 isoform X1. (351 aa)
TECRLTrans-2,3-enoyl-CoA reductase-like. (363 aa)
DUS1LDihydrouridine synthase 1 like. (474 aa)
ACADSShort-chain specific acyl-CoA dehydrogenase, mitochondrial; Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chai [...] (612 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (377 aa)
PTGR1Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. (329 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (745 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
ACAD9Acyl-CoA dehydrogenase family member 9, mitochondrial isoform X1. (621 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (664 aa)
BLVRBFlavin reductase (NADPH). (206 aa)
DUS4LtRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (329 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
BDH23-hydroxybutyrate dehydrogenase type 2 isoform X2. (245 aa)
FASNUncharacterized protein. (1430 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase. (303 aa)
LOC100525350S5A_REDUCTASE domain-containing protein. (318 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa)
SRD5A1S5A_REDUCTASE domain-containing protein. (517 aa)
AKR1D13-oxo-5-beta-steroid 4-dehydrogenase isoform 1. (326 aa)
TBXAS1Thromboxane-A synthase; Belongs to the cytochrome P450 family. (535 aa)
ACADLLong-chain specific acyl-CoA dehydrogenase, mitochondrial; Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Among the different mitochondrial acyl-CoA dehydrogenas [...] (430 aa)
DUS3LtRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (652 aa)
TM7SF2Transmembrane 7 superfamily member 2. (399 aa)
CPOXUncharacterized protein. (443 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (780 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1036 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase 2; Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology (By similarity). (346 aa)
RETSATAll-trans-retinol 13,14-reductase. (611 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (973 aa)
PTGES2Prostaglandin E synthase 2. (372 aa)
BAXTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (432 aa)
PPOXProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (550 aa)
GCDHGlutaryl-CoA dehydrogenase, mitochondrial; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L- hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. (438 aa)
TECRS5A_REDUCTASE domain-containing protein. (528 aa)
BLVRABiliverdin reductase A. (438 aa)
DECR2Peroxisomal 2,4-dienoyl-CoA reductase. (320 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (720 aa)
DHODHDihydroorotate dehydrogenase (quinone). (421 aa)
A0A5G2QSB6_PIGUncharacterized protein. (146 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). (454 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (681 aa)
DECR1Uncharacterized protein. (348 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (328 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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