STRINGSTRING
FADS1 FADS1 CYP2F1 CYP2F1 CYP2A19 CYP2A19 KDM1A KDM1A LOC100522145 LOC100522145 CYP4A24 CYP4A24 F1S3X0_PIG F1S3X0_PIG MOXD1 MOXD1 MICAL1 MICAL1 TYRP1 TYRP1 DBH DBH SQLE SQLE CYP7B1 CYP7B1 LOC100151788 LOC100151788 FMO5 FMO5 PTGIS PTGIS FADS3 FADS3 CYP24A1 CYP24A1 CYP2W1 CYP2W1 KDM8 KDM8 JMJD8 JMJD8 PHF2 PHF2 TET3 TET3 CYP26B1 CYP26B1 TET2 TET2 SCD5 SCD5 OGFOD2 OGFOD2 SCD SCD LOC102167481 LOC102167481 KDM5D KDM5D CYP2E1 CYP2E1 EGLN2-2 EGLN2-2 P4HB P4HB KMO KMO P3H4 P3H4 PLOD1 PLOD1 AGMO AGMO HMOX1 HMOX1 EGLN2 EGLN2 MICAL2 MICAL2 PHYHD1 PHYHD1 PLOD3 PLOD3 CYP21A2 CYP21A2 CYP4A21 CYP4A21 PAH PAH JMJD6 JMJD6 CMAH CMAH SAAL1 SAAL1 COQ6 COQ6 NOS2 NOS2 CH25H CH25H KDM4B KDM4B CYP39A1 CYP39A1 CYP2C36 CYP2C36 CYP4F3 CYP4F3 NOS1 NOS1 KDM6B KDM6B CYP1B1 CYP1B1 ALKBH5 ALKBH5 PAM PAM A0A287A6V0_PIG A0A287A6V0_PIG CYP2S1 CYP2S1 CYP8B1 CYP8B1 KDM4C KDM4C CYP2R1 CYP2R1 CYP51A1 CYP51A1 AKR1C1 AKR1C1 OGFOD1 OGFOD1 DOHH DOHH METTL26 METTL26 LOC110260194 LOC110260194 CYP4B1 CYP4B1 CRTAP CRTAP PTGS1 PTGS1 TTI2 TTI2 A0A287ARF8_PIG A0A287ARF8_PIG CYP19A1 CYP19A1 ASPH ASPH FTO FTO TH TH NOS3 NOS3 CCNDBP1 CCNDBP1 CYP4V2 CYP4V2 HMOX2 HMOX2 FADS2 FADS2 CYP4F2 CYP4F2 HIF1AN HIF1AN MICAL3 MICAL3 FMO1 FMO1 P4HA2 P4HA2 HSPBAP1 HSPBAP1 KDM5A KDM5A DEGS2 DEGS2 MICAL2-2 MICAL2-2 KDM2A KDM2A FMO3 FMO3 FMO2 FMO2 TYW5 TYW5 LOC100511166 LOC100511166 KDM7A KDM7A TBXAS1 TBXAS1 AKR1D1 AKR1D1 TMLHE TMLHE PHF8 PHF8 KDM5C KDM5C P3H2 P3H2 PLOD2 PLOD2 P4HTM P4HTM KDM5B KDM5B CYP17A1 CYP17A1 CYP2C33 CYP2C33 CYP26A1 CYP26A1 CYP26C1 CYP26C1 TET1 TET1 EGLN1 EGLN1 ALKBH2 ALKBH2 KDM2B KDM2B CYP46A1 CYP46A1 EGLN3 EGLN3 CYP1A1 CYP1A1 CYP1A2 CYP1A2 KDM1B KDM1B P3H3 P3H3 TPH2 TPH2 CYP2D25 CYP2D25 SC5D SC5D TMEM189 TMEM189 P4HA3 P4HA3 ALKBH1 ALKBH1 PIGS PIGS CYP2B22 CYP2B22 DEGS1 DEGS1 LOC100523745 LOC100523745 RSBN1 RSBN1 CYP4F22 CYP4F22 ALKBH4 ALKBH4 CYP11A1 CYP11A1 CYP27B1 CYP27B1 CYP4F8 CYP4F8 CYP3A22 CYP3A22 I3LDQ8_PIG I3LDQ8_PIG CYP27A1 CYP27A1 ALKBH8 ALKBH8 LOC100627093 LOC100627093 P3H1 P3H1 LOC100737508 LOC100737508 I3L6E6_PIG I3L6E6_PIG FADS6 FADS6 KDM4A KDM4A TYR TYR CCDC160 CCDC160 CYP2J34 CYP2J34 KDM6A KDM6A NLRP11 NLRP11 RIOX2 RIOX2 OGFOD3 OGFOD3 A0A286ZQC2_PIG A0A286ZQC2_PIG CYP7A1 CYP7A1 LOC110255328 LOC110255328 PTGS2 PTGS2 P4HA1 P4HA1 A0A286ZW25_PIG A0A286ZW25_PIG MSMO1 MSMO1 LOC110256857 LOC110256857 KDM3A KDM3A PHYH PHYH COQ7 COQ7 CYP2U1 CYP2U1 RIOX1 RIOX1 FMO4 FMO4 JMJD4 JMJD4 BBOX1 BBOX1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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protein homology
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FADS1Cytochrome b5 heme-binding domain-containing protein. (481 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (492 aa)
CYP2A19Cytochorme P450 2A19; Belongs to the cytochrome P450 family. (494 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa)
LOC100522145Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
CYP4A24Cytochrome P450 4A24; Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Has no activity toward taurochenodeoxycholic acid; Belongs to the cytochrome P450 family. (482 aa)
F1S3X0_PIGUncharacterized protein. (285 aa)
MOXD1Monooxygenase DBH like 1. (612 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1122 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (562 aa)
DBHDopamine beta-hydroxylase. (610 aa)
SQLESqualene monooxygenase. (574 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa)
LOC100151788Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
FMO5Flavin-containing monooxygenase. (418 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (503 aa)
FADS3Fatty acid desaturase 3. (443 aa)
CYP24A125-hydroxyvitamin D3-24-hydroxylase; Belongs to the cytochrome P450 family. (514 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (469 aa)
KDM8JmjC domain-containing protein 5 isoform 1. (406 aa)
JMJD8JmjC domain-containing protein 8 isoform 1. (269 aa)
PHF2PHD finger protein 2. (1107 aa)
TET3Tet methylcytosine dioxygenase 3. (1660 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
TET2Tet methylcytosine dioxygenase 2. (2019 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (332 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa)
SCDAcyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid ox [...] (425 aa)
LOC102167481Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
KDM5DLysine demethylase 5D. (1506 aa)
CYP2E1Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (499 aa)
EGLN2-2Fe2OG dioxygenase domain-containing protein. (125 aa)
P4HBProtein disulfide-isomerase. (623 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (547 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (455 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (726 aa)
AGMOAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (451 aa)
HMOX1Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. (287 aa)
EGLN2Uncharacterized protein. (257 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (959 aa)
PHYHD1Phytanoyl-CoA dioxygenase domain containing 1. (295 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa)
CYP21A2Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. (526 aa)
CYP4A21Cytochrome P450 4A24; Belongs to the cytochrome P450 family. (529 aa)
PAHPhenylalanine hydroxylase. (450 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa)
CMAHCytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. (596 aa)
SAAL1Serum amyloid A like 1. (490 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (481 aa)
NOS2Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1195 aa)
CH25HCholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. Plays a key role in cell positioning and movement in lymphoid tissues: 25- hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25- dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory eleme [...] (311 aa)
KDM4BLysine demethylase 4B. (1213 aa)
CYP39A1Uncharacterized protein; Belongs to the cytochrome P450 family. (461 aa)
CYP2C36Cytochrome P450 2C42; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (843 aa)
CYP4F3Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (524 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
KDM6BLysine demethylase 6B. (1638 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
PAMPeptidyl-glycine alpha-amidating monooxygenase isoform X1. (972 aa)
A0A287A6V0_PIGUncharacterized protein. (155 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (650 aa)
CYP8B15-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Involved in bile acid synthesis and is responsible for the conversion of 5 beta-cholestane-3-alpha,7-alpha-diol into 5 beta- cholestane-3-alpha,7-alpha,12-alpha triol. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. The enzyme can also hydroxylate the substrate at the 25 and 26 position, but to a lesser extent. (501 aa)
KDM4CLysine demethylase 4C. (1056 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (500 aa)
CYP51A1Lanosterol 14-alpha demethylase; A cytochrome P450 monooxygenase involved in sterol biosynthesis. Catalyzes 14-alpha demethylation of lanosterol and 24,25- dihydrolanosterol likely through sequential oxidative conversion of 14- alpha methyl group to hydroxymethyl, then to carboxylaldehyde, followed by the formation of the delta 14,15 double bond in the sterol core and concomitant release of formic acid. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P45 [...] (503 aa)
AKR1C1Aldo-keto reductase family 1 member C3 isoform 2. (324 aa)
OGFOD12-oxoglutarate and iron dependent oxygenase domain containing 1. (560 aa)
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (305 aa)
METTL26Methyltransferase like 26. (204 aa)
LOC110260194Cytochrome P450 11B1, mitochondrial; A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) [...] (503 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (459 aa)
CRTAPCartilage-associated protein. (401 aa)
PTGS1Prostaglandin G/H synthase 1 isoform 1. (600 aa)
TTI2TELO2 interacting protein 2. (507 aa)
A0A287ARF8_PIGUncharacterized protein. (161 aa)
CYP19A1Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. (551 aa)
ASPHAspartate beta-hydroxylase. (788 aa)
FTOFTO_NTD domain-containing protein. (509 aa)
THTyrosine hydroxylase. (596 aa)
NOS3Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity). (1239 aa)
CCNDBP1Cyclin-D1-binding protein 1. (357 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
HMOX2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
FADS2Cytochrome b5 heme-binding domain-containing protein. (712 aa)
CYP4F2Phylloquinone omega-hydroxylase CYP4F2; Belongs to the cytochrome P450 family. (524 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (361 aa)
MICAL3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2098 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. (554 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha 2. (555 aa)
HSPBAP1HSPB1 associated protein 1. (502 aa)
KDM5ALysine-specific demethylase 5A. (1690 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (341 aa)
MICAL2-2BMERB domain-containing protein. (710 aa)
KDM2ALysine demethylase 2A. (1164 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
TYW5tRNA wybutosine-synthesizing protein 5. (315 aa)
LOC100511166DOMON domain-containing protein. (614 aa)
KDM7ALysine-specific demethylase 7A. (942 aa)
TBXAS1Thromboxane-A synthase; Belongs to the cytochrome P450 family. (535 aa)
AKR1D13-oxo-5-beta-steroid 4-dehydrogenase isoform 1. (326 aa)
TMLHETrimethyllysine dioxygenase, mitochondrial isoform 1. (421 aa)
PHF8PHD finger protein 8. (1060 aa)
KDM5CLysine-specific demethylase 5C; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity). (1516 aa)
P3H2Prolyl 3-hydroxylase 2 isoform a. (706 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (760 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (496 aa)
KDM5BLysine-specific demethylase 5B isoform 2. (1547 aa)
CYP17A1Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (509 aa)
CYP2C33Cytochrome P450 2C8 isoform a; Belongs to the cytochrome P450 family. (494 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
TET1CXXC-type domain-containing protein. (2149 aa)
EGLN1Uncharacterized protein. (427 aa)
ALKBH2AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (260 aa)
KDM2BLysine demethylase 2B. (1312 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (501 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (538 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
KDM1BLysine demethylase 1B. (992 aa)
P3H3Prolyl 3-hydroxylase 3. (727 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
CYP2D25Vitamin D(3) 25-hydroxylase; Catalyzes the first step in the metabolic activation of vitamin D(3) into 1-alpha,25-dihydroxyvitamin D(3), its active, hormonal form. (500 aa)
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (336 aa)
TMEM189Transmembrane protein 189. (271 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha-3 isoform 1. (544 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (425 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (622 aa)
CYP2B22Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
DEGS1Sphingolipid delta(4)-desaturase DES1 isoform 1. (323 aa)
LOC100523745Dimethylaniline monooxygenase [N-oxide-forming]. (578 aa)
RSBN1Round spermatid basic protein 1. (796 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (384 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the sec [...] (520 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (678 aa)
CYP3A22Cytochrome P450 3A29; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (667 aa)
I3LDQ8_PIGUncharacterized protein. (420 aa)
CYP27A1Uncharacterized protein; Belongs to the cytochrome P450 family. (581 aa)
ALKBH8AlkB homolog 8, tRNA methyltransferase. (614 aa)
LOC100627093Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
P3H1Prolyl 3-hydroxylase 1 isoform 1. (698 aa)
LOC100737508Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
I3L6E6_PIGTPR_REGION domain-containing protein. (218 aa)
FADS6Fatty acid desaturase 6. (344 aa)
KDM4AUncharacterized protein. (1066 aa)
TYRTyrosinase. (531 aa)
CCDC160Coiled-coil domain-containing protein 160 isoform X1. (324 aa)
CYP2J34Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa)
KDM6ALysine demethylase 6A. (1400 aa)
NLRP11Uncharacterized protein. (734 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (464 aa)
OGFOD3P4Hc domain-containing protein. (470 aa)
A0A286ZQC2_PIGUncharacterized protein. (502 aa)
CYP7A1Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] (554 aa)
LOC110255328Uncharacterized protein; Belongs to the cytochrome P450 family. (507 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha-1 isoform 1. (534 aa)
A0A286ZW25_PIGUncharacterized protein. (80 aa)
MSMO1Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family. (293 aa)
LOC110256857Uncharacterized protein. (162 aa)
KDM3ALysine demethylase 3A. (1323 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (334 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (667 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (544 aa)
JMJD4JmjC domain-containing protein 4 isoform X1. (424 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (387 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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