Your Input: | |||||
FADS1 | Cytochrome b5 heme-binding domain-containing protein. (481 aa) | ||||
CYP2F1 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (492 aa) | ||||
CYP2A19 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. (494 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa) | ||||
LOC100522145 | Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa) | ||||
CYP4A24 | Cytochrome P450 4A24; Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Has no activity toward taurochenodeoxycholic acid; Belongs to the cytochrome P450 family. (482 aa) | ||||
F1S3X0_PIG | Uncharacterized protein. (285 aa) | ||||
MOXD1 | Monooxygenase DBH like 1. (612 aa) | ||||
MICAL1 | Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1122 aa) | ||||
TYRP1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase. (562 aa) | ||||
DBH | Dopamine beta-hydroxylase. (610 aa) | ||||
SQLE | Squalene monooxygenase. (574 aa) | ||||
CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa) | ||||
LOC100151788 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) | ||||
FMO5 | Flavin-containing monooxygenase. (418 aa) | ||||
PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (503 aa) | ||||
FADS3 | Fatty acid desaturase 3. (443 aa) | ||||
CYP24A1 | 25-hydroxyvitamin D3-24-hydroxylase; Belongs to the cytochrome P450 family. (514 aa) | ||||
CYP2W1 | Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (469 aa) | ||||
KDM8 | JmjC domain-containing protein 5 isoform 1. (406 aa) | ||||
JMJD8 | JmjC domain-containing protein 8 isoform 1. (269 aa) | ||||
PHF2 | PHD finger protein 2. (1107 aa) | ||||
TET3 | Tet methylcytosine dioxygenase 3. (1660 aa) | ||||
CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) | ||||
TET2 | Tet methylcytosine dioxygenase 2. (2019 aa) | ||||
SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (332 aa) | ||||
OGFOD2 | 2-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa) | ||||
SCD | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid ox [...] (425 aa) | ||||
LOC102167481 | Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa) | ||||
KDM5D | Lysine demethylase 5D. (1506 aa) | ||||
CYP2E1 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (499 aa) | ||||
EGLN2-2 | Fe2OG dioxygenase domain-containing protein. (125 aa) | ||||
P4HB | Protein disulfide-isomerase. (623 aa) | ||||
KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (547 aa) | ||||
P3H4 | Prolyl 3-hydroxylase family member 4 (non-enzymatic). (455 aa) | ||||
PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (726 aa) | ||||
AGMO | Alkylglycerol monooxygenase; Belongs to the sterol desaturase family. (451 aa) | ||||
HMOX1 | Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. (287 aa) | ||||
EGLN2 | Uncharacterized protein. (257 aa) | ||||
MICAL2 | Microtubule associated monooxygenase, calponin and LIM domain containing 2. (959 aa) | ||||
PHYHD1 | Phytanoyl-CoA dioxygenase domain containing 1. (295 aa) | ||||
PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa) | ||||
CYP21A2 | Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. (526 aa) | ||||
CYP4A21 | Cytochrome P450 4A24; Belongs to the cytochrome P450 family. (529 aa) | ||||
PAH | Phenylalanine hydroxylase. (450 aa) | ||||
JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa) | ||||
CMAH | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. (596 aa) | ||||
SAAL1 | Serum amyloid A like 1. (490 aa) | ||||
COQ6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (481 aa) | ||||
NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1195 aa) | ||||
CH25H | Cholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. Plays a key role in cell positioning and movement in lymphoid tissues: 25- hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25- dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory eleme [...] (311 aa) | ||||
KDM4B | Lysine demethylase 4B. (1213 aa) | ||||
CYP39A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (461 aa) | ||||
CYP2C36 | Cytochrome P450 2C42; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (843 aa) | ||||
CYP4F3 | Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (524 aa) | ||||
NOS1 | Nitric oxide synthase 1. (1468 aa) | ||||
KDM6B | Lysine demethylase 6B. (1638 aa) | ||||
CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) | ||||
ALKBH5 | AlkB homolog 5, RNA demethylase. (394 aa) | ||||
PAM | Peptidyl-glycine alpha-amidating monooxygenase isoform X1. (972 aa) | ||||
A0A287A6V0_PIG | Uncharacterized protein. (155 aa) | ||||
CYP2S1 | Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (650 aa) | ||||
CYP8B1 | 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Involved in bile acid synthesis and is responsible for the conversion of 5 beta-cholestane-3-alpha,7-alpha-diol into 5 beta- cholestane-3-alpha,7-alpha,12-alpha triol. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. The enzyme can also hydroxylate the substrate at the 25 and 26 position, but to a lesser extent. (501 aa) | ||||
KDM4C | Lysine demethylase 4C. (1056 aa) | ||||
CYP2R1 | Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (500 aa) | ||||
CYP51A1 | Lanosterol 14-alpha demethylase; A cytochrome P450 monooxygenase involved in sterol biosynthesis. Catalyzes 14-alpha demethylation of lanosterol and 24,25- dihydrolanosterol likely through sequential oxidative conversion of 14- alpha methyl group to hydroxymethyl, then to carboxylaldehyde, followed by the formation of the delta 14,15 double bond in the sterol core and concomitant release of formic acid. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P45 [...] (503 aa) | ||||
AKR1C1 | Aldo-keto reductase family 1 member C3 isoform 2. (324 aa) | ||||
OGFOD1 | 2-oxoglutarate and iron dependent oxygenase domain containing 1. (560 aa) | ||||
DOHH | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (305 aa) | ||||
METTL26 | Methyltransferase like 26. (204 aa) | ||||
LOC110260194 | Cytochrome P450 11B1, mitochondrial; A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) [...] (503 aa) | ||||
CYP4B1 | Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (459 aa) | ||||
CRTAP | Cartilage-associated protein. (401 aa) | ||||
PTGS1 | Prostaglandin G/H synthase 1 isoform 1. (600 aa) | ||||
TTI2 | TELO2 interacting protein 2. (507 aa) | ||||
A0A287ARF8_PIG | Uncharacterized protein. (161 aa) | ||||
CYP19A1 | Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. (551 aa) | ||||
ASPH | Aspartate beta-hydroxylase. (788 aa) | ||||
FTO | FTO_NTD domain-containing protein. (509 aa) | ||||
TH | Tyrosine hydroxylase. (596 aa) | ||||
NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity). (1239 aa) | ||||
CCNDBP1 | Cyclin-D1-binding protein 1. (357 aa) | ||||
CYP4V2 | Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa) | ||||
HMOX2 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa) | ||||
FADS2 | Cytochrome b5 heme-binding domain-containing protein. (712 aa) | ||||
CYP4F2 | Phylloquinone omega-hydroxylase CYP4F2; Belongs to the cytochrome P450 family. (524 aa) | ||||
HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (361 aa) | ||||
MICAL3 | Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2098 aa) | ||||
FMO1 | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. (554 aa) | ||||
P4HA2 | Prolyl 4-hydroxylase subunit alpha 2. (555 aa) | ||||
HSPBAP1 | HSPB1 associated protein 1. (502 aa) | ||||
KDM5A | Lysine-specific demethylase 5A. (1690 aa) | ||||
DEGS2 | Delta 4-desaturase, sphingolipid 2. (341 aa) | ||||
MICAL2-2 | BMERB domain-containing protein. (710 aa) | ||||
KDM2A | Lysine demethylase 2A. (1164 aa) | ||||
FMO3 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) | ||||
FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) | ||||
TYW5 | tRNA wybutosine-synthesizing protein 5. (315 aa) | ||||
LOC100511166 | DOMON domain-containing protein. (614 aa) | ||||
KDM7A | Lysine-specific demethylase 7A. (942 aa) | ||||
TBXAS1 | Thromboxane-A synthase; Belongs to the cytochrome P450 family. (535 aa) | ||||
AKR1D1 | 3-oxo-5-beta-steroid 4-dehydrogenase isoform 1. (326 aa) | ||||
TMLHE | Trimethyllysine dioxygenase, mitochondrial isoform 1. (421 aa) | ||||
PHF8 | PHD finger protein 8. (1060 aa) | ||||
KDM5C | Lysine-specific demethylase 5C; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity). (1516 aa) | ||||
P3H2 | Prolyl 3-hydroxylase 2 isoform a. (706 aa) | ||||
PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (760 aa) | ||||
P4HTM | Prolyl 4-hydroxylase, transmembrane. (496 aa) | ||||
KDM5B | Lysine-specific demethylase 5B isoform 2. (1547 aa) | ||||
CYP17A1 | Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (509 aa) | ||||
CYP2C33 | Cytochrome P450 2C8 isoform a; Belongs to the cytochrome P450 family. (494 aa) | ||||
CYP26A1 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa) | ||||
CYP26C1 | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa) | ||||
TET1 | CXXC-type domain-containing protein. (2149 aa) | ||||
EGLN1 | Uncharacterized protein. (427 aa) | ||||
ALKBH2 | AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (260 aa) | ||||
KDM2B | Lysine demethylase 2B. (1312 aa) | ||||
CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (501 aa) | ||||
EGLN3 | Egl-9 family hypoxia inducible factor 3. (239 aa) | ||||
CYP1A1 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (538 aa) | ||||
CYP1A2 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa) | ||||
KDM1B | Lysine demethylase 1B. (992 aa) | ||||
P3H3 | Prolyl 3-hydroxylase 3. (727 aa) | ||||
TPH2 | Tryptophan hydroxylase 2. (491 aa) | ||||
CYP2D25 | Vitamin D(3) 25-hydroxylase; Catalyzes the first step in the metabolic activation of vitamin D(3) into 1-alpha,25-dihydroxyvitamin D(3), its active, hormonal form. (500 aa) | ||||
SC5D | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (336 aa) | ||||
TMEM189 | Transmembrane protein 189. (271 aa) | ||||
P4HA3 | Prolyl 4-hydroxylase subunit alpha-3 isoform 1. (544 aa) | ||||
ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (425 aa) | ||||
PIGS | Phosphatidylinositol glycan anchor biosynthesis class S. (622 aa) | ||||
CYP2B22 | Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa) | ||||
DEGS1 | Sphingolipid delta(4)-desaturase DES1 isoform 1. (323 aa) | ||||
LOC100523745 | Dimethylaniline monooxygenase [N-oxide-forming]. (578 aa) | ||||
RSBN1 | Round spermatid basic protein 1. (796 aa) | ||||
CYP4F22 | Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa) | ||||
ALKBH4 | AlkB homolog 4, lysine demethylase. (384 aa) | ||||
CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the sec [...] (520 aa) | ||||
CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa) | ||||
CYP4F8 | Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (678 aa) | ||||
CYP3A22 | Cytochrome P450 3A29; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (667 aa) | ||||
I3LDQ8_PIG | Uncharacterized protein. (420 aa) | ||||
CYP27A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (581 aa) | ||||
ALKBH8 | AlkB homolog 8, tRNA methyltransferase. (614 aa) | ||||
LOC100627093 | Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa) | ||||
P3H1 | Prolyl 3-hydroxylase 1 isoform 1. (698 aa) | ||||
LOC100737508 | Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa) | ||||
I3L6E6_PIG | TPR_REGION domain-containing protein. (218 aa) | ||||
FADS6 | Fatty acid desaturase 6. (344 aa) | ||||
KDM4A | Uncharacterized protein. (1066 aa) | ||||
TYR | Tyrosinase. (531 aa) | ||||
CCDC160 | Coiled-coil domain-containing protein 160 isoform X1. (324 aa) | ||||
CYP2J34 | Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa) | ||||
KDM6A | Lysine demethylase 6A. (1400 aa) | ||||
NLRP11 | Uncharacterized protein. (734 aa) | ||||
RIOX2 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (464 aa) | ||||
OGFOD3 | P4Hc domain-containing protein. (470 aa) | ||||
A0A286ZQC2_PIG | Uncharacterized protein. (502 aa) | ||||
CYP7A1 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] (554 aa) | ||||
LOC110255328 | Uncharacterized protein; Belongs to the cytochrome P450 family. (507 aa) | ||||
PTGS2 | Prostaglandin G/H synthase 2. (604 aa) | ||||
P4HA1 | Prolyl 4-hydroxylase subunit alpha-1 isoform 1. (534 aa) | ||||
A0A286ZW25_PIG | Uncharacterized protein. (80 aa) | ||||
MSMO1 | Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family. (293 aa) | ||||
LOC110256857 | Uncharacterized protein. (162 aa) | ||||
KDM3A | Lysine demethylase 3A. (1323 aa) | ||||
PHYH | Phytanoyl-CoA 2-hydroxylase. (334 aa) | ||||
COQ7 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa) | ||||
CYP2U1 | Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa) | ||||
RIOX1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (667 aa) | ||||
FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (544 aa) | ||||
JMJD4 | JmjC domain-containing protein 4 isoform X1. (424 aa) | ||||
BBOX1 | Gamma-butyrobetaine hydroxylase 1. (387 aa) |