(13 nodes) Retinal binding network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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Predicted Interactions

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Your Input:
	RBP4	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family. (238 aa)
	OPN5	Opsin 5; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	CRABP1	Cellular retinoic acid-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
	RHO	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa)
	RBP3	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina. (1284 aa)
	ADH4	Alcohol dehydrogenase 4 isoform 2. (380 aa)
	CYP2W1	Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (469 aa)
	ABCA4	ATP binding cassette subfamily A member 4. (2320 aa)
	CRABP2	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
	STRA6	Stimulated by retinoic acid 6. (666 aa)
	RBP2	Retinol-binding protein 2; Intracellular transport of retinol. (184 aa)
	OPN4	Opsin 4. (488 aa)
	RLBP1	Retinaldehyde binding protein 1. (384 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA4	RBP3	ENSSSCP00000007345	ENSSSCP00000011062	ATP binding cassette subfamily A member 4.	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	0.525
ABCA4	RHO	ENSSSCP00000007345	ENSSSCP00000012353	ATP binding cassette subfamily A member 4.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.680
ABCA4	RLBP1	ENSSSCP00000007345	ENSSSCP00000041134	ATP binding cassette subfamily A member 4.	Retinaldehyde binding protein 1.	0.443
CRABP1	STRA6	ENSSSCP00000023870	ENSSSCP00000002088	Cellular retinoic acid-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Stimulated by retinoic acid 6.	0.451
CRABP2	STRA6	ENSSSCP00000006897	ENSSSCP00000002088	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Stimulated by retinoic acid 6.	0.551
OPN5	RHO	ENSSSCP00000027454	ENSSSCP00000012353	Opsin 5; Belongs to the G-protein coupled receptor 1 family.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.601
RBP2	RBP4	ENSSSCP00000071182	ENSSSCP00000038691	Retinol-binding protein 2; Intracellular transport of retinol.	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	0.526
RBP2	STRA6	ENSSSCP00000071182	ENSSSCP00000002088	Retinol-binding protein 2; Intracellular transport of retinol.	Stimulated by retinoic acid 6.	0.430
RBP3	ABCA4	ENSSSCP00000011062	ENSSSCP00000007345	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	ATP binding cassette subfamily A member 4.	0.525
RBP3	RHO	ENSSSCP00000011062	ENSSSCP00000012353	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.831
RBP3	RLBP1	ENSSSCP00000011062	ENSSSCP00000041134	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	Retinaldehyde binding protein 1.	0.554
RBP3	STRA6	ENSSSCP00000011062	ENSSSCP00000002088	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	Stimulated by retinoic acid 6.	0.451
RBP4	RBP2	ENSSSCP00000038691	ENSSSCP00000071182	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	Retinol-binding protein 2; Intracellular transport of retinol.	0.526
RBP4	STRA6	ENSSSCP00000038691	ENSSSCP00000002088	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	Stimulated by retinoic acid 6.	0.801
RHO	ABCA4	ENSSSCP00000012353	ENSSSCP00000007345	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	ATP binding cassette subfamily A member 4.	0.680
RHO	OPN5	ENSSSCP00000012353	ENSSSCP00000027454	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	Opsin 5; Belongs to the G-protein coupled receptor 1 family.	0.601
RHO	RBP3	ENSSSCP00000012353	ENSSSCP00000011062	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	0.831
RHO	RLBP1	ENSSSCP00000012353	ENSSSCP00000041134	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	Retinaldehyde binding protein 1.	0.680
RLBP1	ABCA4	ENSSSCP00000041134	ENSSSCP00000007345	Retinaldehyde binding protein 1.	ATP binding cassette subfamily A member 4.	0.443
RLBP1	RBP3	ENSSSCP00000041134	ENSSSCP00000011062	Retinaldehyde binding protein 1.	Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.	0.554