STRINGSTRING
TGFB2 TGFB2 EXT1 EXT1 BMI1 BMI1 GNL3 GNL3 WWTR1 WWTR1 FZD7 FZD7 STRA8 STRA8 HOXB4 HOXB4 FUT10 FUT10 WNT3A WNT3A ING2 ING2 ZBTB16 ZBTB16 CUL3 CUL3 NOTCH1 NOTCH1 SAMD9 SAMD9 FUT11 FUT11 NANOG NANOG ZFP36L2 ZFP36L2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
BMI1RING-type domain-containing protein. (336 aa)
GNL3G protein nucleolar 3. (551 aa)
WWTR1WW domain containing transcription regulator 1. (398 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
STRA8Stimulated by retinoic acid 8. (365 aa)
HOXB4Homeobox B4. (278 aa)
FUT10Fucosyltransferase 10. (543 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ING2Inhibitor of growth protein. (280 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
CUL3Cullin 3; Belongs to the cullin family. (773 aa)
NOTCH1Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
SAMD9Sterile alpha motif domain containing 9. (1596 aa)
FUT11Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (493 aa)
NANOGHomeobox domain-containing protein. (304 aa)
ZFP36L2ZFP36 ring finger protein like 2. (564 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.