STRINGSTRING
ATXN7L2 ATXN7L2 PIAS3 PIAS3 TADA1 TADA1 ESCO1 ESCO1 CTH CTH SETBP1 SETBP1 ARID4A ARID4A NSD2 NSD2 TET2 TET2 SETDB2 SETDB2 OGFOD2 OGFOD2 HNF1A HNF1A EGR2 EGR2 SIRT1 SIRT1 KAT6B KAT6B LOXL4 LOXL4 LDB1 LDB1 TAF5 TAF5 SUV39H2 SUV39H2 BMI1 BMI1 WDR82 WDR82 LOC100514009 LOC100514009 SETD5 SETD5 BRPF1 BRPF1 TADA3 TADA3 MSL2 MSL2 PLOD2 PLOD2 ACTL6A ACTL6A SENP2 SENP2 SENP5 SENP5 MORF4L2 MORF4L2 MEN1 MEN1 MYOD1 MYOD1 CTR9 CTR9 PWP1 PWP1 KMT2D KMT2D MCRS1 MCRS1 P3H3 P3H3 ACRBP ACRBP POU5F1 POU5F1 BAG6 BAG6 EHMT2 EHMT2 ZNF451 ZNF451 NFYA NFYA SUPT3H SUPT3H WDR61 WDR61 MORF4L1 MORF4L1 LOXL1 LOXL1 KMT2B KMT2B RUVBL2 RUVBL2 CHD5 CHD5 PARK7 PARK7 KIAA2013 KIAA2013 MLLT1 MLLT1 DHPS DHPS LOX LOX RBBP5 RBBP5 SMYD2 SMYD2 EPC2 EPC2 HAT1 HAT1 CBX4 CBX4 SUMO2 SUMO2 KANSL1 KANSL1 ATXN7L3 ATXN7L3 EZH1 EZH1 KAT2A KAT2A MBTD1 MBTD1 ASH1L ASH1L SMYD3 SMYD3 RUVBL1 RUVBL1 ASH2L ASH2L EP400 EP400 SPHK2 SPHK2 N6AMT1 N6AMT1 ATAT1 ATAT1 EP300 EP300 MCM3AP MCM3AP BRD8 BRD8 LIPT2 LIPT2 TAF10 TAF10 SENP7 SENP7 LIAS LIAS MUL1 MUL1 RNF212B RNF212B C6orf136 C6orf136 RTF1 RTF1 HDAC10 HDAC10 RANBP2 RANBP2 SETD4 SETD4 SGF29 SGF29 USPL1 USPL1 TAF1 TAF1 TAF6L TAF6L ZMPSTE24 ZMPSTE24 KAT2B KAT2B DOT1L DOT1L TAF4 TAF4 UBE2I UBE2I DYDC2 DYDC2 BRCA2 BRCA2 OGT OGT PER1 PER1 TAF2 TAF2 JADE3 JADE3 NFYC NFYC METTL21A METTL21A USP22 USP22 TAF5L TAF5L JADE2 JADE2 ENY2 ENY2 ZNF335 ZNF335 PAX6 PAX6 LEF1 LEF1 YEATS2 YEATS2 SETDB1 SETDB1 TRIM28 TRIM28 JADE1 JADE1 ACTB ACTB EPC1 EPC1 PAXIP1 PAXIP1 KDM3A KDM3A PCGF2 PCGF2 MLLT6 MLLT6 YEATS4 YEATS4 A0A287A298_PIG A0A287A298_PIG SIRT7 SIRT7 EYA1 EYA1 MEAF6 MEAF6 CLOCK CLOCK ING3 ING3 EEF1AKMT3 EEF1AKMT3 NAT8 NAT8 IRF4 IRF4 PHF20L1 PHF20L1 KMT2C KMT2C NDUFAB1 NDUFAB1 A0A287ABJ1_PIG A0A287ABJ1_PIG PIAS4 PIAS4 SUPT7L SUPT7L DPY30 DPY30 CAMKMT CAMKMT BRD1 BRD1 NAA50 NAA50 SUMO3 SUMO3 DOHH DOHH SIRT5 SIRT5 CXXC1 CXXC1 ATXN7L1 ATXN7L1 NAA60 NAA60 TRRAP TRRAP SETD7 SETD7 KMT2A KMT2A IFIH1 IFIH1 LOXL2 LOXL2 TOPORS TOPORS TAF12 TAF12 METTL8 METTL8 UBA2 UBA2 PRDM7 PRDM7 ING5 ING5 GCC1 GCC1 SENP3 SENP3 ZZZ3 ZZZ3 ETFBKMT ETFBKMT PRDM5 PRDM5 ATPSCKMT ATPSCKMT TRPM4 TRPM4 A0A287AU63_PIG A0A287AU63_PIG EZH2 EZH2 NCOA1 NCOA1 BEND3 BEND3 DMAP1 DMAP1 FOXP3 FOXP3 METTL21C METTL21C METTL18 METTL18 LOC102165734 LOC102165734 SUV39H1 SUV39H1 VPS72 VPS72 SENP6 SENP6 PNO1 PNO1 VCPKMT VCPKMT SETD2 SETD2 TAF6 TAF6 ATF2 ATF2 A0A287B8J8_PIG A0A287B8J8_PIG GCSH GCSH ATXN7 ATXN7 SMC5 SMC5 SETD3 SETD3 EHMT1 EHMT1 SENP1 SENP1 KAT6A KAT6A LOC100737265 LOC100737265 KANSL2 KANSL2 MAP3K7 MAP3K7 CSKMT CSKMT DESI1 DESI1 HDAC6 HDAC6 KMT5B KMT5B TEX30 TEX30 VIPAS39 VIPAS39 TRIM16 TRIM16 TRIM38 TRIM38 KMT5C KMT5C RLF RLF MBD3 MBD3 A0A5G2Q7V0_PIG A0A5G2Q7V0_PIG SMYD5 SMYD5 JMJD6 JMJD6 CREBBP CREBBP GTF3C4 GTF3C4 POLE3 POLE3 STX1A STX1A KAT8 KAT8 SETD6 SETD6 KMT5A KMT5A MSL3 MSL3 MSL1 MSL1 MECP2 MECP2 PLOD3 PLOD3 NSMCE2 NSMCE2 TAF9 TAF9 KANSL3 KANSL3 SIRT2 SIRT2 RNF212 RNF212 SAE1 SAE1 NCOA3 NCOA3 KAT14 KAT14 EEF2KMT EEF2KMT KAT5 KAT5 ING4 ING4 LOXL3 LOXL3 PLOD1 PLOD1 P3H4 P3H4 DR1 DR1 PIAS1 PIAS1 RANGAP1 RANGAP1 WDR5 WDR5 PIAS2 PIAS2 FKBP10 FKBP10 KAT7 KAT7 SIRT3 SIRT3 DMRTC2 DMRTC2 BRPF3 BRPF3 SUMO1 SUMO1 MBIP MBIP VPS33B VPS33B NAA40 NAA40 SETD1B SETD1B SIRT4 SIRT4 IZUMO4 IZUMO4 SETD1A SETD1A GTF2B GTF2B TET3 TET3 SMYD1 SMYD1 ANTKMT ANTKMT
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATXN7L2Ataxin-7-like protein 2 isoform 1. (754 aa)
PIAS3Protein inhibitor of activated STAT 3. (628 aa)
TADA1Transcriptional adapter 1. (335 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (879 aa)
CTHCystathionine gamma-lyase; Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target protei [...] (420 aa)
SETBP1SET-binding protein isoform X1. (1604 aa)
ARID4AAT-rich interaction domain 4A. (1279 aa)
NSD2Histone-lysine N-methyltransferase NSD2 isoform 1. (1338 aa)
TET2Tet methylcytosine dioxygenase 2. (2019 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (700 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa)
HNF1AHepatocyte nuclear factor 1-alpha isoform 2. (631 aa)
EGR2E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity); Belongs to the EGR C2H2-type zinc-finger protein family. (471 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2065 aa)
LOXL4Lysyl oxidase like 4. (757 aa)
LDB1LID domain-containing protein. (411 aa)
TAF5Transcription initiation factor TFIID subunit 5 isoform 1. (800 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (446 aa)
BMI1RING-type domain-containing protein. (336 aa)
WDR82WD repeat domain 82. (313 aa)
LOC100514009Histone-lysine N-methyltransferase SETMAR isoform 1. (306 aa)
SETD5SET domain containing 5. (1456 aa)
BRPF1Uncharacterized protein. (1214 aa)
TADA3Transcriptional adapter 3 isoform a. (432 aa)
MSL2E3 ubiquitin-protein ligase MSL2 isoform 1. (577 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (760 aa)
ACTL6AActin-like protein 6A isoform X1; Belongs to the actin family. (429 aa)
SENP2SUMO specific peptidase 2. (557 aa)
SENP5SUMO specific peptidase 5. (752 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
MEN1Menin 1. (704 aa)
MYOD1Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1169 aa)
PWP1PWP1 homolog, endonuclein. (499 aa)
KMT2DUncharacterized protein. (116 aa)
MCRS1Microspherule protein 1. (487 aa)
P3H3Prolyl 3-hydroxylase 3. (727 aa)
ACRBPAcrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. (539 aa)
POU5F1POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. (361 aa)
BAG6Large proline-rich protein BAG6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1163 aa)
EHMT2Uncharacterized protein. (1233 aa)
ZNF451Zinc finger protein 451. (1061 aa)
NFYANuclear transcription factor Y subunit alpha. (346 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (423 aa)
WDR61WD repeat-containing protein 61 isoform a. (305 aa)
MORF4L1Mortality factor 4-like protein 1 isoform 2. (362 aa)
LOXL1Lysyl oxidase like 1. (591 aa)
KMT2BLysine methyltransferase 2B. (2595 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (525 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1976 aa)
PARK7DJ-1 protein. (189 aa)
KIAA2013KIAA2013. (647 aa)
MLLT1MLLT1 super elongation complex subunit. (556 aa)
DHPSDeoxyhypusine synthase isoform X1. (369 aa)
LOXProtein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family. (419 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (517 aa)
SMYD2N-lysine methyltransferase SMYD2; Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'; Belongs to the class V-like SAM-binding methyltransferase superfamily. (538 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (418 aa)
CBX4Chromobox 4. (547 aa)
SUMO2Small ubiquitin-related modifier 2; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO [...] (95 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (1103 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (347 aa)
EZH1Uncharacterized protein. (750 aa)
KAT2ALysine acetyltransferase 2A. (857 aa)
MBTD1Mbt domain containing 1. (715 aa)
ASH1LASH1 like histone lysine methyltransferase. (2963 aa)
SMYD3Histone-lysine N-methyltransferase SMYD3 isoform 1. (428 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (635 aa)
EP400E1A binding protein p400. (3210 aa)
SPHK2Sphingosine kinase 2. (653 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1. (220 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (421 aa)
EP300E1A binding protein p300. (2420 aa)
MCM3APMinichromosome maintenance complex component 3 associated protein. (1860 aa)
BRD8Bromodomain containing 8. (1236 aa)
LIPT2Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. (225 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa)
SENP7Sentrin-specific protease 7 isoform X1. (1051 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (410 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (305 aa)
RNF212BRing finger protein 212B. (300 aa)
C6orf136Chromosome 6 open reading frame 136. (315 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (769 aa)
HDAC10Histone deacetylase 10. (671 aa)
RANBP2RAN binding protein 2. (3233 aa)
SETD4SET domain containing 4. (440 aa)
SGF29SAGA complex associated factor 29. (328 aa)
USPL1SUMO-specific isopeptidase USPL1 isoform X1. (1095 aa)
TAF1Transcription initiation factor TFIID subunit. (2001 aa)
TAF6LTATA-box binding protein associated factor 6 like. (603 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (831 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1720 aa)
TAF4TATA-box binding protein associated factor 4. (1031 aa)
UBE2IUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (409 aa)
DYDC2DPY30 domain containing 2. (202 aa)
BRCA2Tower domain-containing protein. (1163 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross- talk between glycosylation and phosphorylation or by affecting proteolytic processing. Probably by glycosylating [...] (1074 aa)
PER1Period circadian regulator 1. (1278 aa)
TAF2TATA-box binding protein associated factor 2. (1251 aa)
JADE3Jade family PHD finger 3. (833 aa)
NFYCNuclear transcription factor Y subunit gamma. (456 aa)
METTL21AMethyltransferase like 21A. (218 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (522 aa)
TAF5LTATA-box binding protein associated factor 5 like. (624 aa)
JADE2Jade family PHD finger 2. (784 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
ZNF335Zinc finger protein 335. (1354 aa)
PAX6Paired box 6. (498 aa)
LEF1Lymphoid enhancer binding factor 1. (429 aa)
YEATS2YEATS domain containing 2. (1368 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1332 aa)
TRIM28Tripartite motif containing 28. (868 aa)
JADE1Jade family PHD finger 1. (857 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
EPC1Enhancer of polycomb homolog. (841 aa)
PAXIP1PAX interacting protein 1. (1030 aa)
KDM3ALysine demethylase 3A. (1323 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (344 aa)
MLLT6MLLT6, PHD finger containing. (1093 aa)
YEATS4YEATS domain containing 4. (227 aa)
A0A287A298_PIGRad60-SLD domain-containing protein. (60 aa)
SIRT7Sirtuin 7. (447 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
MEAF6MYST/Esa1 associated factor 6. (216 aa)
CLOCKClock circadian regulator. (857 aa)
ING3Inhibitor of growth protein. (418 aa)
EEF1AKMT3EEF1A lysine methyltransferase 3 isoform a. (226 aa)
NAT8N-acetyltransferase domain-containing protein. (237 aa)
IRF4Interferon regulatory factor 4. (451 aa)
PHF20L1PHD finger protein 20 like 1. (1024 aa)
KMT2CLysine methyltransferase 2C. (4977 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
A0A287ABJ1_PIGUncharacterized protein. (163 aa)
PIAS4Protein inhibitor of activated STAT 4. (566 aa)
SUPT7LSTAGA complex 65 subunit gamma isoform b. (412 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
CAMKMTCalmodulin-lysine N-methyltransferase. (323 aa)
BRD1Bromodomain containing 1. (1187 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (168 aa)
SUMO3Small ubiquitin-related modifier. (101 aa)
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (305 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (308 aa)
CXXC1CXXC finger protein 1. (665 aa)
ATXN7L1Ataxin 7 like 1. (1013 aa)
NAA60N(alpha)-acetyltransferase 60, NatF catalytic subunit. (327 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3858 aa)
SETD7SET domain containing 7, histone lysine methyltransferase. (539 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4000 aa)
IFIH1Interferon induced with helicase C domain 1. (1023 aa)
LOXL2Lysyl oxidase like 2. (758 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1049 aa)
TAF12Transcription initiation factor TFIID subunit 12 isoform X1. (213 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (426 aa)
UBA2Uncharacterized protein. (395 aa)
PRDM7PR/SET domain 7. (466 aa)
ING5Inhibitor of growth family member 5. (273 aa)
GCC1GRIP and coiled-coil domain-containing protein 1. (775 aa)
SENP3Sentrin-specific protease 3. (574 aa)
ZZZ3ZZ-type zinc finger-containing protein 3 isoform X1. (903 aa)
ETFBKMTUncharacterized protein. (264 aa)
PRDM5Zinc finger protein. (630 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (228 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4 isoform X1. (1213 aa)
A0A287AU63_PIGUBIQUITIN_CONJUGAT_2 domain-containing protein. (149 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (762 aa)
NCOA1Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...] (1441 aa)
BEND3BEN domain-containing protein 3 isoform X1. (832 aa)
DMAP1DNA methyltransferase 1-associated protein 1 isoform X1. (468 aa)
FOXP3Forkhead box protein P3 isoform a. (475 aa)
METTL21CMethyltransferase like 21C. (260 aa)
METTL18Methyltransferase like 18. (373 aa)
LOC102165734Uncharacterized protein. (231 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (462 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog isoform 2. (364 aa)
SENP6Sentrin-specific protease 6 isoform 1. (1145 aa)
PNO1RNA-binding protein PNO1 isoform 1. (252 aa)
VCPKMTValosin containing protein lysine methyltransferase. (229 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2557 aa)
TAF6TATA-box binding protein associated factor 6. (705 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
A0A287B8J8_PIGUncharacterized protein. (617 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
ATXN7SCA7 domain-containing protein. (893 aa)
SMC5AAA_23 domain-containing protein. (1106 aa)
SETD3Protein-histidine N-methyltransferase. (595 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1299 aa)
SENP1SUMO specific peptidase 1. (677 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (829 aa)
LOC100737265Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post- translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for insta [...] (101 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (491 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CSKMTCitrate synthase-lysine N-methyltransferase CSKMT, mitochondrial isoform X1. (240 aa)
DESI1Desumoylating isopeptidase 1. (235 aa)
HDAC6Histone deacetylase 6. (1159 aa)
KMT5BLysine methyltransferase 5B. (915 aa)
TEX30Testis expressed 30. (225 aa)
VIPAS39VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (539 aa)
TRIM16Uncharacterized protein. (582 aa)
TRIM38E3 ubiquitin-protein ligase TRIM38 isoform X1. (465 aa)
KMT5CLysine methyltransferase 5C. (455 aa)
RLFZinc finger protein Rlf isoform X1. (1915 aa)
MBD3Methyl-CpG binding domain protein 3. (291 aa)
A0A5G2Q7V0_PIGUncharacterized protein. (123 aa)
SMYD5SET and MYND domain-containing protein 5 isoform X1. (596 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa)
CREBBPCREB-binding protein isoform a. (2440 aa)
GTF3C4General transcription factor 3C polypeptide 4. (679 aa)
POLE3Uncharacterized protein. (171 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (295 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (461 aa)
SETD6SET domain containing 6, protein lysine methyltransferase. (446 aa)
KMT5ALysine methyltransferase 5A. (496 aa)
MSL3MSL complex subunit 3. (606 aa)
MSL1MSL complex subunit 1. (624 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (489 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (275 aa)
TAF9Transcription initiation factor TFIID subunit 9. (265 aa)
KANSL3KAT8 regulatory NSL complex subunit 3. (877 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa)
RNF212RING-type domain-containing protein. (262 aa)
SAE1SUMO1 activating enzyme subunit 1. (385 aa)
NCOA3Uncharacterized protein. (1296 aa)
KAT14Lysine acetyltransferase 14. (784 aa)
EEF2KMTUncharacterized protein. (365 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (576 aa)
ING4Inhibitor of growth family member 4. (277 aa)
LOXL3Lysyl oxidase like 3. (814 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (726 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (455 aa)
DR1Down-regulator of transcription 1. (176 aa)
PIAS1Protein inhibitor of activated STAT 1. (685 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
WDR5WD repeat domain 5. (389 aa)
PIAS2Protein inhibitor of activated STAT 2. (612 aa)
FKBP10Peptidylprolyl isomerase. (576 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (351 aa)
DMRTC2DMRT like family C2. (372 aa)
BRPF3Bromodomain and PHD finger containing 3. (1150 aa)
SUMO1Small ubiquitin-related modifier 1. (141 aa)
MBIPMAP3K12 binding inhibitory protein 1. (375 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (650 aa)
NAA40N(alpha)-acetyltransferase 40, NatD catalytic subunit. (239 aa)
SETD1BUncharacterized protein. (113 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (371 aa)
IZUMO4IZUMO family member 4. (307 aa)
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1703 aa)
GTF2BGeneral transcription factor IIB. (337 aa)
TET3Tet methylcytosine dioxygenase 3. (1660 aa)
SMYD1SET and MYND domain containing 1. (539 aa)
ANTKMTAdenine nucleotide translocase lysine methyltransferase. (226 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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