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| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | F1SBK3_PIG | Uncharacterized protein. (103 aa) |
| | PKIA | cAMP-dependent protein kinase inhibitor alpha; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains; Belongs to the PKI family. (119 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | DAB2IP | DAB2 interacting protein. (1196 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (131 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | RPLP1 | 60S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (322 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (396 aa) |
| | IBTK | Inhibitor of Bruton tyrosine kinase. (1345 aa) |
| | F1RTU6_PIG | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (108 aa) |
| | MOB3C | MOB kinase activator 3C. (240 aa) |
| | CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) |
| | CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (201 aa) |
| | CCNE1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (410 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (605 aa) |
| | TCL1A | Uncharacterized protein. (54 aa) |
| | TCL1B | T-cell leukemia/lymphoma protein 1B. (128 aa) |
| | CIB1 | Calcium and integrin-binding protein 1 isoform b. (191 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1709 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (163 aa) |
| | DAXX | Death domain associated protein. (751 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (859 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] (298 aa) |
| | ANKRD54 | Ankyrin repeat domain 54. (397 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1201 aa) |
| | MOB1B | MOB kinase activator 1B. (242 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) |
| | RAC2 | Rac family small GTPase 2. (217 aa) |
| | SPRY4 | Sprouty RTK signaling antagonist 4. (325 aa) |
| | HEXIM1 | HEXIM P-TEFb complex subunit 1. (348 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | INCA1 | Uncharacterized protein. (295 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (445 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1205 aa) |
| | A0A5G2RBJ3_PIG | Tyrosine-protein kinase receptor. (542 aa) |
| | ITPRIP | Inositol 1,4,5-trisphosphate receptor interacting protein. (583 aa) |
| | A0A5G2QST0_PIG | Uncharacterized protein. (115 aa) |
| | EREG | Epiregulin. (168 aa) |
| | CCNJ | Cyclin J; Belongs to the cyclin family. (452 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1128 aa) |
| | PRKRIP1 | PRKR interacting protein 1. (238 aa) |
| | PARVA | Parvin alpha. (373 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | MOB2 | MOB kinase activator 2. (373 aa) |
| | DGKQ | Diacylglycerol kinase. (987 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1164 aa) |
| | STRADB | STE20 related adaptor beta. (430 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (331 aa) |
| | HBEGF | Proheparin-binding EGF-like growth factor; Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor (By similarity). (276 aa) |
| | CCNJL | Cyclin J like; Belongs to the cyclin family. (536 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (454 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (373 aa) |
| | CCNI | Cyclin-I isoform X2; Belongs to the cyclin family. (377 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa) |
| | GPRC5A | G protein-coupled receptor class C group 5 member A. (360 aa) |
| | GPRC5D | G protein-coupled receptor class C group 5 member D. (395 aa) |
| | IGF2 | Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...] (583 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | MOB3B | MOB kinase activator 3B. (329 aa) |
| | A0A287BHR5_PIG | Uncharacterized protein. (50 aa) |
| | CCNL2 | Cyclin-L2 isoform A; Belongs to the cyclin family. (530 aa) |
| | KIDINS220 | Kinase D interacting substrate 220. (1782 aa) |
| | ITPRIPL2 | Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1789 aa) |
| | SMCR8 | SMCR8-C9orf72 complex subunit. (935 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] (288 aa) |
| | TRIB2 | Tribbles pseudokinase 2. (343 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | A0A287B846_PIG | DBF4-type domain-containing protein. (317 aa) |
| | GCN1 | GCN1 activator of EIF2AK4. (2679 aa) |
| | CDC37 | CDC37 cell division cycle 37 protein. (380 aa) |
| | ALKAL1 | ALK and LTK ligand 1. (121 aa) |
| | GAS6 | Uncharacterized protein. (682 aa) |
| | MOB1A | MOB kinase activator 1A. (214 aa) |
| | LOC110259300 | Uncharacterized protein; Belongs to the cyclin family. (347 aa) |
| | GPRC5C | G protein-coupled receptor class C group 5 member C. (454 aa) |
| | ELP4 | Elongator acetyltransferase complex subunit 4. (476 aa) |
| | CNPPD1 | Cyclin Pas1/PHO80 domain containing 1. (440 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (967 aa) |
| | CDKN1B | p27Kip1. (198 aa) |
| | ARMC9 | LisH domain-containing protein ARMC9 isoform 1. (864 aa) |
| | CCNF | Cyclin F; Belongs to the cyclin family. (788 aa) |
| | PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. (433 aa) |
| | FGFR1OP | FGFR1 oncogene partner. (399 aa) |
| | WNK1 | Serine/threonine-protein kinase WNK1; Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thia [...] (2350 aa) |
| | PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. (389 aa) |
| | NKPD1 | NTPase KAP family P-loop domain containing 1. (573 aa) |
| | NRG1 | Neuregulin 1. (712 aa) |
| | HEXIM2 | HEXIM P-TEFb complex subunit 2. (293 aa) |
| | A0A287ADN3_PIG | Uncharacterized protein. (93 aa) |
| | INKA2 | PAK4-inhibitor INKA2 isoform X1. (292 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (262 aa) |
| | DBF4B | DBF4 zinc finger B. (640 aa) |
| | ALS2 | Alsin Rho guanine nucleotide exchange factor ALS2. (1662 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | GSKIP | DUF727 domain-containing protein. (282 aa) |
| | SPRY3 | Sprouty RTK signaling antagonist 3. (288 aa) |
| | ELP3 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (638 aa) |
| | CCNH | Cyclin-H isoform 1; Belongs to the cyclin family. (328 aa) |
| | CCNG2 | Cyclin G2; Belongs to the cyclin family. (344 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1338 aa) |
| | CCNC | Cyclin C; Belongs to the cyclin family. (350 aa) |
| | DBF4 | DBF4-type domain-containing protein. (675 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) |
| | APC | APC_basic domain-containing protein. (2713 aa) |
| | BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) |
| | BTC | EGF-like domain-containing protein. (342 aa) |
| | TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa) |
| | STRADA | STE20 related adaptor alpha. (432 aa) |
| | ALKAL2 | ALK and LTK ligand 2. (152 aa) |
| | MOB3A | MOB kinase activator 3A. (304 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | ETAA1 | Ewing's tumor-associated antigen 1 isoform X2. (899 aa) |
| | MT3 | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa) |
| | P14ARF | ANK_REP_REGION domain-containing protein. (159 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (468 aa) |
| | QARS1 | Glutamine--tRNA ligase isoform a; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa) |
| | CCNY | Cyclin Y; Belongs to the cyclin family. (416 aa) |
| | A0A286ZHX0_PIG | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (117 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | ALK | Uncharacterized protein. (1034 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | K7GMK8_PIG | Signal transducer CD24 isoform a preproprotein. (78 aa) |
| | MTCP1 | Mature T cell proliferation 1. (107 aa) |
| | CSNK2B | Casein kinase II subunit beta; Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). (298 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1194 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (831 aa) |
| | LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | PKIG | cAMP-dependent protein kinase inhibitor gamma; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. (76 aa) |
| | CAMK2N1 | Uncharacterized protein. (158 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | CCNO | Cyclin-O; Belongs to the cyclin family. (351 aa) |
| | SH3BP5 | SH3 domain binding protein 5. (452 aa) |
| | BMPR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | RACK1 | Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression (By similarity). Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (By similarity). Binds to [...] (317 aa) |
| | CCNB1 | Cyclin B1 transcript variant 1; Belongs to the cyclin family. (435 aa) |
| | CCNL1 | Cyclin-L1 isoform 1; Belongs to the cyclin family. (526 aa) |
| | SH3BP5L | SH3 binding domain protein 5 like. (425 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator. (365 aa) |
| | DNAJC3 | Uncharacterized protein. (504 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1351 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1342 aa) |
| | CCNYL1 | Cyclin-Y-like protein 1 isoform 3; Belongs to the cyclin family. (363 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (536 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (315 aa) |
| | TOM1L1 | Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (475 aa) |
| | FAM20A | FAM20A golgi associated secretory pathway pseudokinase. (541 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (339 aa) |
| | CCNG1 | Cyclin-G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity); Belongs to the cyclin family. Cyclin G subfamily. (161 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (619 aa) |
| | CAB39 | Calcium-binding protein 39. (341 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] (499 aa) |
| | A0A5G2RI12_PIG | Uncharacterized protein. (55 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (618 aa) |
| | DELE1 | DAP3 binding cell death enhancer 1. (517 aa) |
| | CCNI2 | CYCLIN domain-containing protein; Belongs to the cyclin family. (223 aa) |
| | F1RN65_PIG | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (128 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) |
| | INCENP | Inner centromere protein. (848 aa) |
| | CCNQ | Cyclin Q; Belongs to the cyclin family. (250 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | GHRL | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family. (118 aa) |
| | HYAL2 | Hyaluronidase. (476 aa) |
| | ABI1 | Abl interactor 1 isoform b. (481 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1462 aa) |
| | RGCC | Regulator of cell cycle RGCC. (137 aa) |
| | CAB39L | Calcium binding protein 39 like. (337 aa) |
| | CCNA1 | Cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa) |
| | AREG | Amphiregulin long form. (247 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (295 aa) |
| | SPDYA | Speedy/RINGO cell cycle regulator family member A. (394 aa) |
| | TGFA | Protransforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. (160 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (455 aa) |
| | GPRC5B | G protein-coupled receptor class C group 5 member B. (405 aa) |
| | HSPB1 | Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. (365 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (194 aa) |
| | CIT | Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2104 aa) |
| | CCNT1 | Cyclin T1; Belongs to the cyclin family. (727 aa) |
| | MBIP | MAP3K12 binding inhibitory protein 1. (375 aa) |
