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| | ADTRP | Androgen dependent TFPI regulating protein. (230 aa) |
| | TNFAIP6 | Uncharacterized protein. (277 aa) |
| | SYNJ2BP | Synaptojanin 2 binding protein. (164 aa) |
| | DPEP1 | Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (409 aa) |
| | PFN2 | Profilin; Belongs to the profilin family. (189 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | GCSAM | Uncharacterized protein. (179 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (536 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (289 aa) |
| | NF1 | Neurofibromin 1. (2847 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (99 aa) |
| | NGFR | Nerve growth factor receptor. (414 aa) |
| | JUP | Junction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...] (744 aa) |
| | STAT3 | Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1131 aa) |
| | CCL28 | C-C motif chemokine. (176 aa) |
| | EPHA1 | Ephrin type-A receptor 1. (982 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | MEOX2 | Homeobox domain-containing protein. (303 aa) |
| | DPYSL3 | Dihydropyrimidinase like 3. (683 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (133 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa) |
| | PODNL1 | Podocan like 1. (576 aa) |
| | CALR | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa) |
| | ARHGAP4 | Rho GTPase activating protein 4. (979 aa) |
| | PLXNB3 | Plexin B3. (1894 aa) |
| | TIMP1 | Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa) |
| | HRG | Uncharacterized protein. (561 aa) |
| | PTPRG | Protein tyrosine phosphatase receptor type G. (1452 aa) |
| | NISCH | Nischarin. (1520 aa) |
| | HYAL2 | Hyaluronidase. (476 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | GDF2 | Growth differentiation factor 2. (427 aa) |
| | MIF | Macrophage migration inhibitory factor; Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By simi [...] (115 aa) |
| | TBX5 | T-box transcription factor 5. (535 aa) |
| | LRCH1 | Leucine rich repeats and calponin homology domain containing 1. (771 aa) |
| | STARD13 | Uncharacterized protein. (541 aa) |
| | SFRP2 | Uncharacterized protein. (294 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (295 aa) |
| | SLIT2 | Slit guidance ligand 2. (1542 aa) |
| | ZMYND8 | Zinc finger MYND-type containing 8. (1237 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa) |
| | DLC1 | Rho GTPase-activating protein 7 isoform X1. (1528 aa) |
| | FAM102B | Family with sequence similarity 102 member B. (399 aa) |
| | ADAM15 | Disintegrin and metalloproteinase domain-containing protein 15 isoform 6 preproprotein. (866 aa) |
| | SULF1 | Sulfatase 1. (1108 aa) |
| | CCN3 | Cellular communication network factor 3. (398 aa) |
| | PIP5KL1 | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1. (396 aa) |
| | DAB2IP | DAB2 interacting protein. (1196 aa) |
| | THBS1 | Uncharacterized protein. (1170 aa) |
| | SEMA6D | Semaphorin 6D; Belongs to the semaphorin family. (1086 aa) |
| | FOXO3 | Forkhead box protein O3 isoform X1. (672 aa) |
| | GJA1 | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] (382 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | EMILIN2 | Elastin microfibril interfacer 2. (1078 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (418 aa) |
| | RRAS | RAS related. (218 aa) |
| | C5AR2 | Complement component 5a receptor 2. (434 aa) |
| | VASH1 | Vasohibin 1. (418 aa) |
| | RIN3 | Ras and Rab interactor 3. (918 aa) |
| | MARVELD3 | MARVEL domain-containing protein. (390 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (829 aa) |
| | RIPOR2 | PL48 domain-containing protein. (1063 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (292 aa) |
| | DNAJA4 | Uncharacterized protein. (571 aa) |
| | NR2F2 | Nuclear receptor subfamily 2 group F member 2. (414 aa) |
| | STK26 | Protein kinase domain-containing protein. (576 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1920 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (982 aa) |
| | FAM102A | Family with sequence similarity 102 member A. (415 aa) |
| | ADA | Adenosine deaminase. (409 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | CARD10 | Caspase recruitment domain family member 10. (1244 aa) |
| | CCL25 | C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (445 aa) |
| | TMEFF2 | Transmembrane protein with EGF like and two follistatin like domains 2. (403 aa) |
| | ANGPT2 | Angiopoietin-2; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell- matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). (495 aa) |
| | MYOCD | Myocardin; Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity). (993 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (365 aa) |
| | ROBO1 | Roundabout guidance receptor 1. (1687 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (611 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | ADORA3 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa) |
| | A0A5G2R6Q7_PIG | Uncharacterized protein. (97 aa) |
| | SCAI | Protein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (606 aa) |
| | RABGEF1 | Uncharacterized protein. (503 aa) |
| | DACH1 | Dachshund family transcription factor 1. (707 aa) |
| | RECK | Reversion-inducing cysteine-rich protein with Kazal motifs isoform 1. (971 aa) |
| | MIIP | Migration and invasion inhibitory protein. (422 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (489 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (1292 aa) |
| | WASL | WASP like actin nucleation promoting factor. (511 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | DPP4 | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] (833 aa) |
| | SRGAP2 | Uncharacterized protein. (1087 aa) |
| | RAP2B | Ras-related protein Rap-2a; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading (By similarity). (183 aa) |
| | CDH1 | Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (925 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1. (184 aa) |
| | PTPRU | Protein tyrosine phosphatase receptor type U. (1446 aa) |
| | ADARB1 | Adenosine deaminase RNA specific B1. (702 aa) |
| | NEXMIF | Neurite extension and migration factor. (1514 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | TP53INP1 | Tumor protein p53-inducible nuclear protein 1 isoform X1. (239 aa) |
| | KANK1 | KN motif and ankyrin repeat domains 1. (1331 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | NKX2-1 | NK2 homeobox 1. (399 aa) |
| | ADGRB1 | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1550 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | MMRN2 | Multimerin 2. (931 aa) |
| | PATZ1 | POZ/BTB and AT hook containing zinc finger 1. (581 aa) |
| | CORO1B | Coronin; Belongs to the WD repeat coronin family. (496 aa) |
| | SRGAP1 | SLIT-ROBO Rho GTPase-activating protein 1 isoform X1. (1085 aa) |
| | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3. (1074 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (1028 aa) |
| | ARPIN | Uncharacterized protein. (260 aa) |
| | MITF | Microphthalmia-associated transcription factor isoform 1. (520 aa) |
| | THY1 | Thy-1 cell surface antigen. (165 aa) |
| | EVL | Enah/Vasp-like. (466 aa) |
| | CD74 | Thyroglobulin type-1 domain-containing protein. (347 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (455 aa) |
| | STK24 | Serine/threonine kinase 24. (433 aa) |
| | ARHGDIB | Uncharacterized protein. (200 aa) |
| | LDLRAD4 | Low density lipoprotein receptor class A domain containing 4. (321 aa) |
| | NODAL | Nodal growth differentiation factor. (316 aa) |
| | MMP28 | Matrix metallopeptidase 28. (521 aa) |
| | ADIPOQ | C1q domain-containing protein. (332 aa) |
| | PTPRT | Protein tyrosine phosphatase receptor type T. (1460 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1171 aa) |
| | RHOA | Transforming protein RhoA isoform 1. (193 aa) |
| | BMERB1 | BMERB domain containing 1. (204 aa) |
| | SINHCAF | SIN3-HDAC complex associated factor. (259 aa) |
| | CNN2 | Calponin-2; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (396 aa) |
| | C5 | Complement C5a anaphylatoxin; Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. (1677 aa) |
| | BCR | BCR activator of RhoGEF and GTPase. (1274 aa) |
| | PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1679 aa) |
| | PRKG1 | cGMP-dependent protein kinase. (686 aa) |
| | CLIC4 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (458 aa) |
| | CD200 | OX-2 membrane glycoprotein isoform X2. (301 aa) |
| | TCAF1 | TRPM8 channel associated factor 1. (1013 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | CXCL13 | C-X-C motif chemokine. (111 aa) |
| | BMP10 | Bone morphogenetic protein 10 preproprotein. (423 aa) |
| | ABHD2 | Abhydrolase domain containing 2. (453 aa) |
| | ARID2 | AT-rich interaction domain 2. (1833 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1554 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (337 aa) |
| | TBXA2R | Thromboxane A2 receptor. (343 aa) |
| | PTPRM | Protein tyrosine phosphatase receptor type M. (1507 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform 1. (317 aa) |
| | LOC100626247 | Uncharacterized protein. (140 aa) |
| | AIF1 | Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity). Has a dual influence on glucose-induced insulin secretion: inhibition at low concentration and stimulation at high concentrations. (147 aa) |
| | CCL21 | Putative CCL21 chemokine. (134 aa) |
| | GPR18 | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | RAP2A | Ras-related protein Rap-2a. (183 aa) |
| | ADGRG1 | Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (740 aa) |
| | WDR63 | WD repeat domain 63. (904 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (270 aa) |
| | KLRK1 | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] (221 aa) |
| | COL3A1 | Collagen alpha-1(III) chain preproprotein. (1471 aa) |
| | PDCD10 | Programmed cell death protein 10. (212 aa) |
| | KRIT1 | Uncharacterized protein. (814 aa) |
| | NRG3 | Neuregulin 3. (718 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (353 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | ENG | Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] (619 aa) |
| | IL27RA | Uncharacterized protein. (683 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | APOD | Apolipoprotein D. (228 aa) |
| | CD300A | CMRF35-like molecule 8 isoform 1. (309 aa) |
| | APOH | Beta-2-glycoprotein 1. (345 aa) |
| | CSNK2B | Casein kinase II subunit beta; Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). (298 aa) |
| | NDRG4 | NDRG family member 4. (454 aa) |
| | SERPINE1 | Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa) |
| | NAV3 | Neuron navigator 3. (2383 aa) |
| | PHLDB2 | Pleckstrin homology like domain family B member 2. (1253 aa) |
| | PADI2 | Peptidyl arginine deiminase 2. (689 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa) |
| | OSBPL8 | Oxysterol-binding protein; Belongs to the OSBP family. (889 aa) |
| | HOXA7 | Homeobox A7. (234 aa) |
| | IGFBP5 | Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (271 aa) |
| | RAP2C | RAP2C, member of RAS oncogene family. (183 aa) |
| | PODN | LRRNT domain-containing protein. (697 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1340 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (511 aa) |
