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DDR2 | Discoidin domain receptor tyrosine kinase 2. (866 aa) | ||||
OSR2 | Odd-skipped related transciption factor 2. (312 aa) | ||||
ANO6 | Anoctamin. (924 aa) | ||||
TENT5A | Terminal nucleotidyltransferase 5A. (434 aa) | ||||
ACVR2B | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] (565 aa) | ||||
CCN1 | Cellular communication network factor 1. (382 aa) | ||||
BMP6 | TGF_BETA_2 domain-containing protein. (537 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) | ||||
ACTN3 | Actinin alpha 3 (gene/pseudogene). (931 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
MGP | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. (127 aa) | ||||
SLC8A1 | Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa) | ||||
LTBP3 | Latent transforming growth factor beta binding protein 3. (1332 aa) | ||||
FBN2 | Fibrillin 2. (2910 aa) | ||||
TXLNG | Gamma-taxilin isoform 1. (512 aa) | ||||
AHSG | Alpha-2-HS-glycoprotein. (394 aa) | ||||
TFAP2A | Transcription factor AP-2 alpha. (439 aa) | ||||
HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (824 aa) | ||||
ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). (418 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (243 aa) | ||||
RFLNB | Refilin-B. (219 aa) | ||||
NBR1 | Next to BRCA1 gene 1 protein isoform X1. (960 aa) | ||||
LOC110257894 | Uncharacterized protein. (552 aa) | ||||
ISG15 | Ubiquitin-like modifier. (167 aa) | ||||
PTN | Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups. Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone (By similarity). Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation (By similarity). Binds PTPRZ1, leading to neutralization of the negative char [...] (215 aa) | ||||
BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) | ||||
ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (878 aa) | ||||
ATP2B1 | Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa) | ||||
RFLNA | Uncharacterized protein. (266 aa) | ||||
ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa) | ||||
GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) | ||||
BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) | ||||
LOC110257970 | ANK_REP_REGION domain-containing protein. (1679 aa) | ||||
OSR1 | Odd-skipped related transcription factor 1. (267 aa) | ||||
NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (570 aa) | ||||
S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) | ||||
TGFB3 | Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi appa [...] (456 aa) | ||||
ALOX5 | Arachidonate 5-lipoxygenase. (638 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) | ||||
BMP2K | BMP2 inducible kinase. (1129 aa) | ||||
LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) | ||||
ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) | ||||
SRGN | Serglycin. (152 aa) | ||||
BMPR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) | ||||
CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa) | ||||
ATRAID | Uncharacterized protein. (236 aa) | ||||
GATA1 | Erythroid transcription factor. (412 aa) | ||||
ECM1 | Extracellular matrix protein 1. (559 aa) | ||||
I3L7W9_PIG | Uncharacterized protein. (373 aa) | ||||
MATN1 | Matrilin 1. (496 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) | ||||
ANKH | ANKH inorganic pyrophosphate transport regulator. (494 aa) | ||||
MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa) | ||||
COMP | Cartilage oligomeric matrix protein. (756 aa) | ||||
PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa) | ||||
BCOR | ANK_REP_REGION domain-containing protein. (693 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) | ||||
KL | Klotho. (1011 aa) | ||||
PKDCC | Protein kinase domain containing, cytoplasmic. (493 aa) | ||||
OMD | Osteomodulin. (422 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (650 aa) | ||||
BGLAP | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa) |