28 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MMP24	Matrix metallopeptidase 24. (635 aa)
	MMP16	Matrix metalloproteinase-16. (607 aa)
	RETREG1	Reticulophagy regulator 1. (565 aa)
	MMP25	Matrix metallopeptidase 25. (566 aa)
	MMP14	Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...] (606 aa)
	PEPD	Peptidase D. (526 aa)
	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif 2. (1204 aa)
	MMP17	Matrix metalloproteinase-17 preproprotein. (595 aa)
	MRC2	Mannose receptor C type 2. (1264 aa)
	RETREG2	Reticulophagy regulator family member 2. (542 aa)
	MMP13	Matrix metallopeptidase 13. (470 aa)
	RETREG3	Reticulophagy regulator family member 3. (466 aa)
	MMP15	Matrix metallopeptidase 15. (712 aa)
	MMP9	Matrix metalloproteinase-9. (708 aa)
	MMP19	Matrix metallopeptidase 19. (506 aa)
	MMP23B	Matrix metallopeptidase 23B. (391 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (341 aa)
	MMP11	Stromelysin-3 preproprotein. (463 aa)
	CTSL	Cathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family. (332 aa)
	CTSV	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (334 aa)
	MMP7	ZnMc domain-containing protein. (267 aa)
	MMP20	Matrix metalloproteinase-20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation (By similarity). (483 aa)
	MMP27	Matrix metallopeptidase 27. (511 aa)
	MMP8	Matrix metallopeptidase 8. (468 aa)
	MMP1	Stromelysin-1 preproprotein. (477 aa)
	MMP12	Macrophage metalloelastase preproprotein. (476 aa)
	MMP28	Matrix metallopeptidase 28. (521 aa)
	MMP2	Uncharacterized protein. (610 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSL	CTSS	ENSSSCP00000011675	ENSSSCP00000007089	Cathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family.	Cathepsin S; Belongs to the peptidase C1 family.	0.941
CTSL	CTSV	ENSSSCP00000011675	ENSSSCP00000011919	Cathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family.	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	0.901
CTSL	MMP9	ENSSSCP00000011675	ENSSSCP00000049256	Cathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family.	Matrix metalloproteinase-9.	0.406
CTSS	CTSL	ENSSSCP00000007089	ENSSSCP00000011675	Cathepsin S; Belongs to the peptidase C1 family.	Cathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family.	0.941
CTSS	CTSV	ENSSSCP00000007089	ENSSSCP00000011919	Cathepsin S; Belongs to the peptidase C1 family.	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	0.941
CTSS	MMP13	ENSSSCP00000007089	ENSSSCP00000015912	Cathepsin S; Belongs to the peptidase C1 family.	Matrix metallopeptidase 13.	0.427
CTSS	MMP9	ENSSSCP00000007089	ENSSSCP00000049256	Cathepsin S; Belongs to the peptidase C1 family.	Matrix metalloproteinase-9.	0.672
CTSV	CTSL	ENSSSCP00000011919	ENSSSCP00000011675	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	Cathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family.	0.901
CTSV	CTSS	ENSSSCP00000011919	ENSSSCP00000007089	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	Cathepsin S; Belongs to the peptidase C1 family.	0.941
CTSV	MMP13	ENSSSCP00000011919	ENSSSCP00000015912	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	Matrix metallopeptidase 13.	0.769
CTSV	MMP7	ENSSSCP00000011919	ENSSSCP00000015905	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	ZnMc domain-containing protein.	0.821
CTSV	MMP9	ENSSSCP00000011919	ENSSSCP00000049256	Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.	Matrix metalloproteinase-9.	0.402
MMP1	MMP11	ENSSSCP00000015910	ENSSSCP00000010744	Stromelysin-1 preproprotein.	Stromelysin-3 preproprotein.	0.619
MMP1	MMP13	ENSSSCP00000015910	ENSSSCP00000015912	Stromelysin-1 preproprotein.	Matrix metallopeptidase 13.	0.601
MMP1	MMP2	ENSSSCP00000015910	ENSSSCP00000073458	Stromelysin-1 preproprotein.	Uncharacterized protein.	0.791
MMP1	MMP7	ENSSSCP00000015910	ENSSSCP00000015905	Stromelysin-1 preproprotein.	ZnMc domain-containing protein.	0.677
MMP1	MMP9	ENSSSCP00000015910	ENSSSCP00000049256	Stromelysin-1 preproprotein.	Matrix metalloproteinase-9.	0.939
MMP11	MMP1	ENSSSCP00000010744	ENSSSCP00000015910	Stromelysin-3 preproprotein.	Stromelysin-1 preproprotein.	0.619
MMP11	MMP2	ENSSSCP00000010744	ENSSSCP00000073458	Stromelysin-3 preproprotein.	Uncharacterized protein.	0.582
MMP11	MMP7	ENSSSCP00000010744	ENSSSCP00000015905	Stromelysin-3 preproprotein.	ZnMc domain-containing protein.	0.583