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| | GRIA1 | Glutamate ionotropic receptor AMPA type subunit 1. (906 aa) |
| | VAMP1 | V-SNARE coiled-coil homology domain-containing protein. (221 aa) |
| | GABRA2 | Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa) |
| | SEC31B | SEC31 homolog B, COPII coat complex component. (1210 aa) |
| | PEF1 | Penta-EF-hand domain containing 1. (334 aa) |
| | VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (189 aa) |
| | MCTP1 | Multiple C2 and transmembrane domain containing 1. (995 aa) |
| | SLC18A1 | Solute carrier family 18 member A1. (524 aa) |
| | RAB3B | RAB3B, member RAS oncogene family. (249 aa) |
| | SCAMP5 | Secretory carrier-associated membrane protein. (252 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (825 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa) |
| | SEC31A | SEC31 homolog A, COPII coat complex component. (1251 aa) |
| | UNC13B | Uncharacterized protein. (4266 aa) |
| | TPRG1L | HSac2 domain-containing protein. (277 aa) |
| | SYNGR3 | Synaptogyrin. (253 aa) |
| | SLC17A7 | Solute carrier family 17 member 7. (567 aa) |
| | CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1702 aa) |
| | TMEM184A | Transmembrane protein 184A. (482 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2759 aa) |
| | A0A5G2QGM6_PIG | Uncharacterized protein. (194 aa) |
| | ICA1 | Islet cell autoantigen 1. (572 aa) |
| | SYNGR2 | Synaptogyrin. (226 aa) |
| | SCGN | Secretagogin. (278 aa) |
| | RPH3A | Rabphilin-3A isoform 1. (701 aa) |
| | SYNGR1 | Synaptogyrin. (234 aa) |
| | SYN2 | Synapsin II. (581 aa) |
| | ATP6AP2 | ATPase H+ transporting accessory protein 2. (353 aa) |
| | USO1 | USO1 vesicle transport factor. (962 aa) |
| | SYNRG | Synergin gamma. (1339 aa) |
| | OTOF | Otoferlin. (1997 aa) |
| | RASSF9 | Ras association domain family member 9. (456 aa) |
| | SYNDIG1 | Synapse differentiation-inducing gene protein 1 isoform X2. (258 aa) |
| | SORL1 | Sortilin related receptor 1. (2213 aa) |
| | SCAMP1 | Secretory carrier-associated membrane protein 1; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface. (326 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa) |
| | KLHL12 | BTB domain-containing protein. (916 aa) |
| | UNC13C | Unc-13 homolog C. (2214 aa) |
| | SLC9B2 | Solute carrier family 9 member B2. (537 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa) |
| | SEC22B | SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (233 aa) |
| | SNAP47 | Synaptosome associated protein 47. (449 aa) |
| | A0A287BA99_PIG | ATP-synt_C domain-containing protein; Belongs to the V-ATPase proteolipid subunit family. (81 aa) |
| | ARFGEF3 | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 isoform X1. (2176 aa) |
| | RPH3AL | Rabphilin 3A like (without C2 domains). (399 aa) |
| | A0A287B6X8_PIG | RING-type domain-containing protein. (509 aa) |
| | RAB26 | RAB26, member RAS oncogene family. (249 aa) |
| | C16orf70 | Chromosome 16 open reading frame 70. (450 aa) |
| | DOC2A | Double C2 domain alpha. (487 aa) |
| | SEMA4C | Semaphorin 4C; Belongs to the semaphorin family. (896 aa) |
| | SVOP | SV2 related protein. (551 aa) |
| | SEC24A | SEC24 homolog A, COPII coat complex component. (1133 aa) |
| | SEPTIN8 | Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (518 aa) |
| | SEC23B | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa) |
| | SV2C | Synaptic vesicle glycoprotein 2C isoform X1. (724 aa) |
| | UNC13A | Uncharacterized protein. (1581 aa) |
| | SV2B | Synaptic vesicle glycoprotein 2B. (683 aa) |
| | PDCD6 | Programmed cell death 6. (292 aa) |
| | SCG3 | Secretogranin III. (549 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (369 aa) |
| | MCTP2 | Multiple C2 and transmembrane domain-containing protein 2 isoform X3. (912 aa) |
| | ATP6V1E1 | ATPase H+ transporting V1 subunit E1. (224 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (258 aa) |
| | SAR1B | GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). (198 aa) |
| | STX6 | Syntaxin 6; Belongs to the syntaxin family. (306 aa) |
| | GOSR2 | Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (225 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa) |
| | CLBA1 | Clathrin binding box of aftiphilin containing 1. (339 aa) |
| | NRGN | Neurogranin. (86 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa) |
| | SAR1A | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). (198 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa) |
| | TMEM30A | Cell cycle control protein; Belongs to the CDC50/LEM3 family. (359 aa) |
| | PAM | Peptidyl-glycine alpha-amidating monooxygenase isoform X1. (972 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (469 aa) |
| | BORCS5 | BLOC-1 related complex subunit 5. (194 aa) |
| | ATP2B1 | Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa) |
| | VMA21 | Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. (267 aa) |
| | SEC16B | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1021 aa) |
| | SEC16A | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2318 aa) |
| | TMED10 | Transmembrane emp24 domain-containing protein 10. (219 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | SREBF1 | Processed sterol regulatory element-binding protein 1; Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3') (By similarity). (1151 aa) |
| | DTNBP1 | Uncharacterized protein. (373 aa) |
| | RAB5A | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa) |
| | SYN3 | Synapsin III. (580 aa) |
| | SYNPR | Synaptoporin. (288 aa) |
| | STX17 | Syntaxin-17 isoform X1; Belongs to the syntaxin family. (302 aa) |
| | BCL2L1 | Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availab [...] (233 aa) |
| | PTPRN2 | Protein tyrosine phosphatase receptor type N2. (1032 aa) |
| | SLC17A8 | Solute carrier family 17 member 8. (544 aa) |
| | SLC18A3 | Solute carrier family 18 member A3. (528 aa) |
| | ATP6V1G2 | V-type proton ATPase subunit G 2; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | SYN1 | Synapsin-1 isoform Ia. (712 aa) |
| | PRRT1 | Uncharacterized protein. (305 aa) |
| | SLC30A3 | Uncharacterized protein. (464 aa) |
| | SYT5 | Synaptotagmin 5. (385 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa) |
| | SCAP | Sterol regulatory element-binding protein cleavage-activating protein; Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP/SREBF complex from the ER upon low cholesterol. Formation of a ternary complex with INSIG at high sterol concentrations leads to masking of an ER-export signal in SCAP and retention of the complex in the ER. Low sterol concentrations trigger release of INSIG, a conformational change in the SSC domain of SCAP, unmasking of the ER export signal, recruitment into COPII-coated vesicles, transport to the Golgi complex, prot [...] (1280 aa) |
| | AFTPH | Aftiphilin. (935 aa) |
| | CA4 | Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (311 aa) |
| | STX12 | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (369 aa) |
| | SYT8 | Synaptotagmin 8. (381 aa) |
| | ATP6V1B2 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (508 aa) |
| | SLC18A2 | MFS domain-containing protein. (517 aa) |
| | PTPRN | Protein tyrosine phosphatase receptor type N. (978 aa) |
| | TMEM163 | Transmembrane protein 163. (287 aa) |
| | SYPL1 | Synaptophysin like 1. (259 aa) |
| | SYT9 | Synaptotagmin-9. (491 aa) |
| | RAB3A | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] (254 aa) |
| | STX10 | Syntaxin 10; Belongs to the syntaxin family. (353 aa) |
| | RAB11B | Uncharacterized protein. (205 aa) |
| | SLC17A6 | Solute carrier family 17 member 6. (582 aa) |
| | SYP | Synaptophysin. (319 aa) |
| | SYT2 | Synaptotagmin 2. (417 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (216 aa) |
| | SEC24C | SEC24 homolog C, COPII coat complex component. (1118 aa) |
| | SEC24B | SEC24 homolog B, COPII coat complex component. (1258 aa) |
| | SEC24D | SEC24 homolog D, COPII coat complex component. (1033 aa) |
| | CPE | Carboxypeptidase E. (475 aa) |
| | CLHC1 | Clathrin heavy chain linker domain-containing protein 1. (586 aa) |
| | STX1A | Syntaxin 1A; Belongs to the syntaxin family. (295 aa) |
| | SLC32A1 | Vesicular inhibitory amino acid transporter. (526 aa) |
| | LAMP5 | Lysosomal associated membrane protein family member 5. (280 aa) |
| | SYPL2 | Synaptophysin like 2. (278 aa) |
| | SLC6A17 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa) |
| | SV2A | Synaptic vesicle glycoprotein 2A isoform 1. (742 aa) |
| | ATP6V1C1 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (397 aa) |
| | DBH | Dopamine beta-hydroxylase. (610 aa) |
| | SYNGR4 | Synaptogyrin. (234 aa) |
| | VTI1B | t-SNARE coiled-coil homology domain-containing protein. (232 aa) |
| | AP1G2 | AP-1 complex subunit gamma. (781 aa) |
| | SEC23A | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa) |
| | CPLX3 | Complexin 3. (158 aa) |
| | SYT1 | Synaptotagmin 1. (379 aa) |
| | LRRK2 | Uncharacterized protein. (2501 aa) |
