(10 nodes) Beta-catenin destruction complex network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AXIN2	Axin-2. (843 aa)
	CTNNBIP1	Beta-catenin-interacting protein 1. (81 aa)
	APC	APC_basic domain-containing protein. (2713 aa)
	APC2	Uncharacterized protein. (2292 aa)
	CACYBP	Calcyclin-binding protein isoform 1. (230 aa)
	CTNNB1	Catenin beta 1. (808 aa)
	AXIN1	Axin 1. (867 aa)
	CSNK1A1	Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. (359 aa)
	DACT1	Dishevelled binding antagonist of beta catenin 1. (807 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (414 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC	APC2	ENSSSCP00000037698	ENSSSCP00000037191	APC_basic domain-containing protein.	Uncharacterized protein.	0.905
APC	AXIN1	ENSSSCP00000037698	ENSSSCP00000072335	APC_basic domain-containing protein.	Axin 1.	0.996
APC	AXIN2	ENSSSCP00000037698	ENSSSCP00000054961	APC_basic domain-containing protein.	Axin-2.	0.977
APC	CSNK1A1	ENSSSCP00000037698	ENSSSCP00000060731	APC_basic domain-containing protein.	Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration.	0.599
APC	CTNNB1	ENSSSCP00000037698	ENSSSCP00000031836	APC_basic domain-containing protein.	Catenin beta 1.	0.997
APC	CTNNBIP1	ENSSSCP00000037698	ENSSSCP00000041866	APC_basic domain-containing protein.	Beta-catenin-interacting protein 1.	0.717
APC	GSK3B	ENSSSCP00000037698	ENSSSCP00000046229	APC_basic domain-containing protein.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.994
APC2	APC	ENSSSCP00000037191	ENSSSCP00000037698	Uncharacterized protein.	APC_basic domain-containing protein.	0.905
APC2	AXIN1	ENSSSCP00000037191	ENSSSCP00000072335	Uncharacterized protein.	Axin 1.	0.876
APC2	AXIN2	ENSSSCP00000037191	ENSSSCP00000054961	Uncharacterized protein.	Axin-2.	0.967
APC2	CSNK1A1	ENSSSCP00000037191	ENSSSCP00000060731	Uncharacterized protein.	Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration.	0.524
APC2	CTNNB1	ENSSSCP00000037191	ENSSSCP00000031836	Uncharacterized protein.	Catenin beta 1.	0.979
APC2	CTNNBIP1	ENSSSCP00000037191	ENSSSCP00000041866	Uncharacterized protein.	Beta-catenin-interacting protein 1.	0.804
APC2	GSK3B	ENSSSCP00000037191	ENSSSCP00000046229	Uncharacterized protein.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.959
AXIN1	APC	ENSSSCP00000072335	ENSSSCP00000037698	Axin 1.	APC_basic domain-containing protein.	0.996
AXIN1	APC2	ENSSSCP00000072335	ENSSSCP00000037191	Axin 1.	Uncharacterized protein.	0.876
AXIN1	AXIN2	ENSSSCP00000072335	ENSSSCP00000054961	Axin 1.	Axin-2.	0.784
AXIN1	CSNK1A1	ENSSSCP00000072335	ENSSSCP00000060731	Axin 1.	Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration.	0.809
AXIN1	CTNNB1	ENSSSCP00000072335	ENSSSCP00000031836	Axin 1.	Catenin beta 1.	0.989
AXIN1	CTNNBIP1	ENSSSCP00000072335	ENSSSCP00000041866	Axin 1.	Beta-catenin-interacting protein 1.	0.582