STRINGSTRING
FGF8 FGF8 SETD2 SETD2 PROX1 PROX1 NDEL1 NDEL1 SCYL2 SCYL2 FRS2 FRS2 POU4F1 POU4F1 TOX TOX NOG NOG PCM1 PCM1 HES5 HES5 LOC106506226 LOC106506226 ELAVL4 ELAVL4 NKX2-1 NKX2-1 CNTN2 CNTN2 SYNE2 SYNE2 PHACTR1 PHACTR1 FGF2 FGF2 TTC8 TTC8 SUN2 SUN2 LMX1A LMX1A GLI1 GLI1 TAL2 TAL2 SECISBP2 SECISBP2 TACC2 TACC2 FEZF1 FEZF1 A0A287BRG1_PIG A0A287BRG1_PIG UBA6 UBA6 AKIRIN2 AKIRIN2 AQP1 AQP1 TNR TNR RTN4R RTN4R FUT1 FUT1 FAM205C FAM205C LHX6 LHX6 DIXDC1 DIXDC1 CCDC85C CCDC85C CSF1R CSF1R RTN4RL1 RTN4RL1 BBS4 BBS4 KIF14 KIF14 INHBA INHBA RTN4 RTN4 CEP120 CEP120 CELF1 CELF1 ZSWIM5 ZSWIM5 HIF1A HIF1A NRP2 NRP2 NOTCH1 NOTCH1 DRD2 DRD2 NIN NIN LRP2 LRP2 HES1 HES1 HOOK3 HOOK3 BTBD3 BTBD3 TACC3 TACC3 SHANK3 SHANK3 OTX1 OTX1 METTL14 METTL14 GSK3B GSK3B EFHC1 EFHC1 RHOA RHOA FOXB1 FOXB1 BMERB1 BMERB1 SUN1 SUN1 APLP1 APLP1 DLX5 DLX5 WNT7A WNT7A FGFR3 FGFR3 SLC4A10 SLC4A10 BAD BAD APAF1 APAF1 EMX2 EMX2 PRKG1 PRKG1 HPRT1 HPRT1 PEX5 PEX5 ZDHHC16 ZDHHC16 NPY NPY SZT2 SZT2 NUMB NUMB SIN3A SIN3A AXL AXL BMPR1A BMPR1A PAX5 PAX5 NTRK2 NTRK2 JAKMIP2 JAKMIP2 HTRA2 HTRA2 PLXNA1 PLXNA1 NKX2-6 NKX2-6 NR4A2 NR4A2 TCTN1 TCTN1 FOXG1 FOXG1 WNT5A WNT5A A0A287A155_PIG A0A287A155_PIG FUT10 FUT10 C12orf57 C12orf57 PTCHD1 PTCHD1 BMP2 BMP2 FBXO45 FBXO45 DLX1 DLX1 LHX2 LHX2 TACC1 TACC1 CREB1 CREB1 BBS1 BBS1 SIX3 SIX3 NEUROD6 NEUROD6 XRCC1 XRCC1 LHX3 LHX3 ADGRG1 ADGRG1 PITX1 PITX1 CRK CRK PAFAH1B1 PAFAH1B1 PEX13 PEX13 LRP8 LRP8 SCT SCT DNAH5 DNAH5 LEF1 LEF1 COL3A1 COL3A1 PAX6 PAX6 ARX ARX NDE1 NDE1 NFIB NFIB NDST1 NDST1 ZNF335 ZNF335 OLIG2 OLIG2 DCLK1 DCLK1 RPGRIP1L RPGRIP1L MCPH1 MCPH1 LRRC45 LRRC45 CTNNB1 CTNNB1 LHX1 LHX1 NRG3 NRG3 PLXNA4 PLXNA4 ALK ALK SRC SRC DCX DCX WNT7B WNT7B PLXNA3 PLXNA3 SLC7A11 SLC7A11 NR2E1 NR2E1 BBS2 BBS2 POU3F3 POU3F3 SEMA3A SEMA3A HESX1 HESX1 PGAP1 PGAP1 NUMBL NUMBL CDON CDON ZSWIM6 ZSWIM6 PTPRS PTPRS CCKAR CCKAR PROP1 PROP1 KRAS KRAS HDAC1 HDAC1 CDK5R2 CDK5R2 SEMA7A SEMA7A WNT3A WNT3A TRA2B TRA2B GDF7 GDF7 PTCHD4 PTCHD4 IGF2BP1 IGF2BP1 DMRTA2 DMRTA2 ATAT1 ATAT1 CDK5 CDK5 AKNA AKNA ATP1B2 ATP1B2 NF1 NF1 CDK5R1 CDK5R1 HAP1 HAP1 KAT2A KAT2A SLC6A3 SLC6A3 ISL1 ISL1 FGF10 FGF10 GLI3 GLI3 OGDH OGDH GHRHR GHRHR SMO SMO SHH SHH GBX2 GBX2 ERBB4 ERBB4 NEUROD1 NEUROD1 CCDC141 CCDC141 DLX2 DLX2 TTC21B TTC21B TBR1 TBR1 RAB3GAP1 RAB3GAP1 LAMB1 LAMB1 RELN RELN SEMA3E SEMA3E KIRREL3 KIRREL3 F1SM96_PIG F1SM96_PIG OTP OTP ZSWIM4 ZSWIM4 SLC1A2 SLC1A2 ZIC3 ZIC3 POU3F4 POU3F4 ATRX ATRX APP APP EPHB3 EPHB3 RYK RYK TMEM108 TMEM108 FEZF2 FEZF2 TOP2B TOP2B AGTPBP1 AGTPBP1 UCHL5 UCHL5 DPCD DPCD SLIT1 SLIT1 ZMIZ1 ZMIZ1 CRKL CRKL NF2 NF2 LHX5 LHX5 TBX3 TBX3 KDM2B KDM2B DCT DCT SLITRK5 SLITRK5 GSX1 GSX1 ATOH1 ATOH1 MGARP MGARP GSX2 GSX2 SLIT2 SLIT2 MSX1 MSX1 VAX2 VAX2 EMX1 EMX1 GHRH GHRH E2F1 E2F1 MKKS MKKS WNT2B WNT2B NHLH2 NHLH2 HSD3B1 HSD3B1 BCAN BCAN NHLH1 NHLH1 CHD7 CHD7 EXT1 EXT1 TRAPPC9 TRAPPC9 DAB2IP DAB2IP BMP4 BMP4 RAX RAX TYRO3 TYRO3 DUOX2 DUOX2 NARS1 NARS1 FYN FYN LHX8 LHX8 POU3F1 POU3F1 EPHB2 EPHB2 DRAXIN DRAXIN MBOAT7 MBOAT7 ATF5 ATF5 BAX BAX ARHGAP35 ARHGAP35 WDR62 WDR62 SALL1 SALL1 BCL11B BCL11B GSC GSC PSEN1 PSEN1 MPP5 MPP5 NR2F2 NR2F2 SRF SRF MDGA1 MDGA1 LRRK2 LRRK2 KCNA1 KCNA1 WNT1 WNT1 ARL13B ARL13B ROBO1 ROBO1 MFSD2A MFSD2A C2orf66 C2orf66 A0A5G2RBJ3_PIG A0A5G2RBJ3_PIG TWSG1 TWSG1 TSKU TSKU OPHN1 OPHN1 RAPGEF2 RAPGEF2 C21orf91 C21orf91 TSC1 TSC1 ALDH1A2 ALDH1A2 ALDH1A3 ALDH1A3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2557 aa)
PROX1Prospero homeobox 1. (737 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (394 aa)
SCYL2SCY1 like pseudokinase 2. (934 aa)
FRS2Fibroblast growth factor receptor substrate 2. (550 aa)
POU4F1POU domain protein. (421 aa)
TOXThymocyte selection associated high mobility group box. (541 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
PCM1Pericentriolar material 1. (2184 aa)
HES5Hes family bHLH transcription factor 5. (226 aa)
LOC106506226TACC_C domain-containing protein. (378 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (487 aa)
NKX2-1NK2 homeobox 1. (399 aa)
CNTN2Contactin 2. (1038 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6940 aa)
PHACTR1Phosphatase and actin regulator. (651 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa)
TTC8Tetratricopeptide repeat domain 8. (587 aa)
SUN2Sad1 and UNC84 domain containing 2. (731 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
TAL2TAL bHLH transcription factor 2. (127 aa)
SECISBP2Selenocysteine insertion sequence-binding protein 2 isoform 1. (848 aa)
TACC2Uncharacterized protein. (2041 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
A0A287BRG1_PIGUncharacterized protein. (210 aa)
UBA6Gonadotropin-releasing hormone receptor; Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G- proteins that activate a phosphatidylinositol-calcium second messenger system. (1396 aa)
AKIRIN2Akirin 2. (213 aa)
AQP1Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (280 aa)
TNRTenascin R. (1270 aa)
RTN4RReticulon 4 receptor. (548 aa)
FUT1Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. (364 aa)
FAM205CUncharacterized protein. (1369 aa)
LHX6LIM homeobox 6. (392 aa)
DIXDC1Calponin-homology (CH) domain-containing protein. (218 aa)
CCDC85CCoiled-coil domain containing 85C. (435 aa)
CSF1RColony stimulating factor 1 receptor. (1053 aa)
RTN4RL1Reticulon 4 receptor like 1. (518 aa)
BBS4Uncharacterized protein. (826 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1532 aa)
INHBAInhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (424 aa)
RTN4Reticulon. (1199 aa)
CEP120Centrosomal protein 120. (992 aa)
CELF1CUGBP Elav-like family member 1. (551 aa)
ZSWIM5Zinc finger SWIM-type containing 5. (1187 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (920 aa)
NOTCH1Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (455 aa)
NINNinein. (2136 aa)
LRP2Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4626 aa)
HES1Uncharacterized protein. (280 aa)
HOOK3Hook microtubule tethering protein 3. (786 aa)
BTBD3BTB/POZ domain-containing protein 3 isoform X1. (527 aa)
TACC3TACC_C domain-containing protein. (783 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1740 aa)
OTX1Orthodenticle homeobox 1. (356 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (414 aa)
EFHC1EF-hand domain containing 1. (665 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
FOXB1Forkhead box protein B1. (325 aa)
BMERB1BMERB domain containing 1. (204 aa)
SUN1Sad1 and UNC84 domain containing 1. (848 aa)
APLP1Amyloid beta precursor like protein 1. (733 aa)
DLX5Homeobox protein DLX-5. (290 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FGFR3Fibroblast growth factor receptor. (855 aa)
SLC4A10Anion exchange protein. (1105 aa)
BADBCL2 associated agonist of cell death. (209 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
HPRT1Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (224 aa)
PEX5Peroxisomal biogenesis factor 5. (660 aa)
ZDHHC16Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (377 aa)
NPYC-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (169 aa)
SZT2SZT2 subunit of KICSTOR complex. (3436 aa)
NUMBNUMB endocytic adaptor protein. (653 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
AXLUncharacterized protein. (871 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PAX5Paired box 5. (390 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
JAKMIP2Janus kinase and microtubule interacting protein 2. (818 aa)
HTRA2HtrA serine peptidase 2. (444 aa)
PLXNA1Plexin A1. (1909 aa)
NKX2-6NK2 homeobox 6. (299 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2 isoform X1. (609 aa)
TCTN1Tectonic family member 1. (772 aa)
FOXG1Forkhead box G1. (486 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
A0A287A155_PIGUncharacterized protein. (58 aa)
FUT10Fucosyltransferase 10. (543 aa)
C12orf57Chromosome 12 open reading frame 57. (126 aa)
PTCHD1Patched domain-containing protein 1. (888 aa)
BMP2Bone morphogenetic protein 2 preproprotein. (395 aa)
FBXO45F-box protein 45. (273 aa)
DLX1Homeobox protein DLX-1 isoform 1. (255 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
TACC1TACC_C domain-containing protein. (801 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
BBS1Bardet-Biedl syndrome 1 protein. (593 aa)
SIX3SIX homeobox 3. (333 aa)
NEUROD6Neurogenic differentiation factor. (337 aa)
XRCC1X-ray repair cross complementing 1. (617 aa)
LHX3LIM/homeobox protein Lhx3; Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). (538 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (740 aa)
PITX1Homeobox protein. (314 aa)
CRKCRK proto-oncogene, adaptor protein. (385 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
LRP8LDL receptor related protein 8. (998 aa)
SCTSecretin; Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis. Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells. Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content. Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the p [...] (135 aa)
DNAH5Dynein axonemal heavy chain 5. (4586 aa)
LEF1Lymphoid enhancer binding factor 1. (429 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1471 aa)
PAX6Paired box 6. (498 aa)
ARXAristaless related homeobox. (563 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X2. (882 aa)
ZNF335Zinc finger protein 335. (1354 aa)
OLIG2Oligodendrocyte transcription factor 2. (323 aa)
DCLK1Doublecortin like kinase 1. (730 aa)
RPGRIP1LProtein fantom isoform X1. (1270 aa)
MCPH1Microcephalin 1. (827 aa)
LRRC45Leucine rich repeat containing 45. (674 aa)
CTNNB1Catenin beta 1. (808 aa)
LHX1LIM homeobox 1. (436 aa)
NRG3Neuregulin 3. (718 aa)
PLXNA4Plexin-A4 isoform X1. (1893 aa)
ALKUncharacterized protein. (1034 aa)
SRCTyrosine-protein kinase. (559 aa)
DCXDoublecortin. (365 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
PLXNA3Plexin A3. (1871 aa)
SLC7A11Solute carrier family 7 member 11. (515 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (727 aa)
POU3F3POU domain, class 3, transcription factor 3; Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity); Belongs to the POU transcription factor family. Class-3 subfamily. (501 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (800 aa)
HESX1HESX homeobox 1. (185 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (933 aa)
NUMBLPID domain-containing protein. (1029 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
ZSWIM6Zinc finger SWIM-type containing 6. (1241 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1946 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
PROP1Homeobox protein prophet of Pit-1; Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. (226 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (365 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (615 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
GDF7Growth differentiation factor 7. (449 aa)
PTCHD4Patched domain containing 4. (901 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
DMRTA2Doublesex-and mab-3-related transcription factor A2. (535 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (421 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
AKNAAT-hook transcription factor. (1429 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (289 aa)
NF1Neurofibromin 1. (2847 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (315 aa)
HAP1Huntingtin associated protein 1. (637 aa)
KAT2ALysine acetyltransferase 2A. (857 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (614 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
GLI3GLI family zinc finger 3. (1586 aa)
OGDHOxoglutarate dehydrogenase. (1035 aa)
GHRHRGrowth hormone-releasing hormone receptor; Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. (451 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
ERBB4Receptor protein-tyrosine kinase. (1201 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CCDC141Ig-like domain-containing protein. (1524 aa)
DLX2Distal-less homeobox 2. (328 aa)
TTC21BTetratricopeptide repeat protein 21B. (1315 aa)
TBR1T-box brain transcription factor 1. (682 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (758 aa)
LAMB1Laminin subunit beta 1. (1785 aa)
RELNReelin. (3458 aa)
SEMA3ESemaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (794 aa)
F1SM96_PIGDIX domain-containing protein. (471 aa)
OTPOrthopedia homeobox. (325 aa)
ZSWIM4Zinc finger SWIM-type containing 4. (1106 aa)
SLC1A2Amino acid transporter. (639 aa)
ZIC3Zic family member 3. (467 aa)
POU3F4POU domain protein. (352 aa)
ATRXATRX chromatin remodeler. (2486 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (756 aa)
EPHB3Ephrin type-B receptor 3. (999 aa)
RYKReceptor like tyrosine kinase. (566 aa)
TMEM108Transmembrane protein 108. (575 aa)
FEZF2FEZ family zinc finger 2. (503 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa)
AGTPBP1ATP/GTP binding protein 1. (1227 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase isozyme L5; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity). (327 aa)
DPCDDeleted in primary ciliary dyskinesia homolog (mouse). (203 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1065 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
NF2Neurofibromin 2. (586 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
TBX3T-box transcription factor TBX3 isoform 2. (745 aa)
KDM2BLysine demethylase 2B. (1312 aa)
DCTL-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (519 aa)
SLITRK5SLIT and NTRK-like protein 5 isoform X1. (963 aa)
GSX1GS homeobox 1. (267 aa)
ATOH1Atonal bHLH transcription factor 1. (353 aa)
MGARPAIF-MLS domain-containing protein. (238 aa)
GSX2GS homeobox 2. (304 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
MSX1Homeobox domain-containing protein. (303 aa)
VAX2Ventral anterior homeobox 2. (288 aa)
EMX1Empty spiracles homeobox 1. (288 aa)
GHRHSomatoliberin; GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone. (106 aa)
E2F1E2F transcription factor 1. (435 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
HSD3B13 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. (373 aa)
BCANBrevican core protein isoform X1. (906 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2863 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
TRAPPC9Trafficking protein particle complex 9. (1147 aa)
DAB2IPDAB2 interacting protein. (1196 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
RAXRetina and anterior neural fold homeobox. (346 aa)
TYRO3TYRO3 protein tyrosine kinase. (913 aa)
DUOX2Dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. (1539 aa)
NARS1Asparagine--tRNA ligase, cytoplasmic. (559 aa)
FYNTyrosine-protein kinase Fyn; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through [...] (537 aa)
LHX8LIM homeobox 8. (377 aa)
POU3F1POU domain protein. (451 aa)
EPHB2EPH receptor B2. (987 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (416 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
ATF5Activating transcription factor 5. (282 aa)
BAXTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
WDR62WD repeat-containing protein 62; Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (By similarity). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). (1541 aa)
SALL1Spalt like transcription factor 1. (1326 aa)
BCL11BUncharacterized protein. (888 aa)
GSCGoosecoid homeobox. (256 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (675 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
SRFSerum response factor. (512 aa)
MDGA1MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein. (955 aa)
LRRK2Uncharacterized protein. (2501 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ARL13BADP ribosylation factor like GTPase 13B. (469 aa)
ROBO1Roundabout guidance receptor 1. (1687 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (541 aa)
C2orf66Chromosome 2 open reading frame 66. (116 aa)
A0A5G2RBJ3_PIGTyrosine-protein kinase receptor. (542 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (291 aa)
TSKUTsukushi, small leucine rich proteoglycan. (357 aa)
OPHN1Oligophrenin 1. (808 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1662 aa)
C21orf91Chromosome 21 open reading frame 91. (344 aa)
TSC1TSC complex subunit 1. (1166 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (527 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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