STRINGSTRING
TSPO TSPO WNT1 WNT1 APOBEC1 APOBEC1 LRRK2 LRRK2 GPLD1 GPLD1 BAG6 BAG6 EHMT2 EHMT2 RNF5 RNF5 PML PML F1SHL4_PIG F1SHL4_PIG PSEN1 PSEN1 NRDE2 NRDE2 N4BP1 N4BP1 PARK7 PARK7 MTOR MTOR PINK1 PINK1 VIP VIP SYNCRIP SYNCRIP TRAF3IP2 TRAF3IP2 TENT5A TENT5A TRAF2 TRAF2 EIF3H EIF3H TENT5C TENT5C E2F1 E2F1 RBM38 RBM38 USP7 USP7 LRPPRC LRPPRC NBAS NBAS F1RWB7_PIG F1RWB7_PIG HNRNPD HNRNPD LZTS1 LZTS1 CCAR2 CCAR2 PBK PBK KLHL22 KLHL22 SUFU SUFU UCHL5 UCHL5 WAC WAC MYD88 MYD88 KLHL40 KLHL40 RUBCN RUBCN TMEM39A TMEM39A TIMP1 TIMP1 TENT5D TENT5D DKC1 DKC1 ELAVL1 ELAVL1 DND1 DND1 IL10RA IL10RA MAPKAPK2 MAPKAPK2 IL10 IL10 DAPL1 DAPL1 HTR2B HTR2B SHH SHH LARP1 LARP1 FOXK2 FOXK2 MEIOC MEIOC BECN1 BECN1 STAT3 STAT3 IKBKE IKBKE PHF23 PHF23 USP14 USP14 IGF2BP1 IGF2BP1 FEZ2 FEZ2 TIGAR TIGAR PABPN1L PABPN1L ZFP36 ZFP36 LEPR LEPR HIPK2 HIPK2 THRAP3 THRAP3 RASIP1 RASIP1 MTMR8 MTMR8 POLDIP2 POLDIP2 LOC100625207 LOC100625207 NOCT NOCT DFFB DFFB TTC36 TTC36 DHX36 DHX36 PABPC1 PABPC1 KDM4A KDM4A NOP53 NOP53 IGF2BP2 IGF2BP2 OGT OGT TRAF5 TRAF5 RBM10 RBM10 DHX9 DHX9 FMR1 FMR1 FUS FUS LOC110258247 LOC110258247 ANXA2 ANXA2 CHMP4A CHMP4A MT3 MT3 PKP3 PKP3 DAP DAP PKP1 PKP1 MTM1 MTM1 PHAX PHAX LOC110261265 LOC110261265 RBM24 RBM24 HNRNPU HNRNPU UBQLN4 UBQLN4 EIF4ENIF1 EIF4ENIF1 TENT2 TENT2 TREM2 TREM2 RNF41 RNF41 TIMP3 TIMP3 DHX34 DHX34 GIPC3 GIPC3 TENT5B TENT5B A1CF A1CF TARDBP TARDBP CAMLG CAMLG USP9X USP9X RYBP RYBP SLC11A1 SLC11A1 TBC1D14 TBC1D14 STYX STYX GDNF GDNF CSNK2A2 CSNK2A2 IGF2BP3 IGF2BP3 PDCL3 PDCL3 INS INS SMARCC1 SMARCC1 TLK2 TLK2 TMEM39B TMEM39B A0A287ANP8_PIG A0A287ANP8_PIG BMF BMF ATP2B4 ATP2B4 PTPN3 PTPN3 ETFBKMT ETFBKMT ADRA1A ADRA1A FHIT FHIT TIMP4 TIMP4 NRBP2 NRBP2 ZCCHC17 ZCCHC17 TP53 TP53 ANGEL2 ANGEL2 SMG1 SMG1 EIF4G1 EIF4G1 FEZ1 FEZ1 SMCR8 SMCR8 ELAVL4 ELAVL4 SEC22B SEC22B AXIN2 AXIN2 FURIN FURIN LOC106510645 LOC106510645 LEP LEP HNRNPAB HNRNPAB CSDE1 CSDE1 SECISBP2 SECISBP2 DDRGK1 DDRGK1 WDR6 WDR6 HFE HFE GIPC2 GIPC2 SORL1 SORL1 BAG5 BAG5 RPL11 RPL11 RBM46 RBM46 NSUN2 NSUN2 PLIN5 PLIN5 LOC100513415 LOC100513415 APOC3 APOC3 UBXN1 UBXN1 TAF9 TAF9 MTMR9 MTMR9 SIRT2 SIRT2 A0A5G2QLC1_PIG A0A5G2QLC1_PIG HMOX1 HMOX1 SGTA SGTA TRIM39 TRIM39 TIMP2 TIMP2 TRDMT1 TRDMT1 MFSD2A MFSD2A ACACB ACACB C3H16orf96 C3H16orf96 HNRNPA0 HNRNPA0 CLEC16A CLEC16A YBX1 YBX1 ENSA ENSA QSOX1 QSOX1 SCFD1 SCFD1 LRIG2 LRIG2 CTSA CTSA DAZL DAZL BOLL BOLL PARN PARN GIPC1 GIPC1 FOXK1 FOXK1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
TSPOTranslocator protein; Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (By similarity); Belongs to the TspO/BZRP family. (169 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa)
LRRK2Uncharacterized protein. (2501 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (906 aa)
BAG6Large proline-rich protein BAG6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1163 aa)
EHMT2Uncharacterized protein. (1233 aa)
RNF5E3 ubiquitin-protein ligase RNF5. (180 aa)
PMLPromyelocytic leukemia. (827 aa)
F1SHL4_PIGUncharacterized protein. (247 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1166 aa)
N4BP1NEDD4-binding protein 1. (897 aa)
PARK7DJ-1 protein. (189 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
PINK1PTEN induced kinase 1. (588 aa)
VIPVasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder; Belongs to the glucagon family. (167 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (623 aa)
TRAF3IP2TRAF3 interacting protein 2. (574 aa)
TENT5ATerminal nucleotidyltransferase 5A. (434 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (327 aa)
TENT5CTerminal nucleotidyltransferase 5C. (423 aa)
E2F1E2F transcription factor 1. (435 aa)
RBM38RNA-binding region (RNP1, RRM) containing 1. (239 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1109 aa)
LRPPRCLeucine-rich PPR motif-containing protein, mitochondrial. (1394 aa)
NBASNeuroblastoma amplified sequence. (2318 aa)
F1RWB7_PIGCSD_1 domain-containing protein. (264 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0 isoform a. (355 aa)
LZTS1Leucine zipper putative tumor suppressor 1 isoform X1. (596 aa)
CCAR2DBC1 domain-containing protein. (916 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase isoform X1. (322 aa)
KLHL22Kelch like family member 22. (634 aa)
SUFUSUFU negative regulator of hedgehog signaling. (432 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase isozyme L5; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity). (327 aa)
WACWW domain containing adaptor with coiled-coil. (646 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (323 aa)
KLHL40Kelch like family member 40. (623 aa)
RUBCNKIAA0226 protein transcript variant 2. (971 aa)
TMEM39ATransmembrane protein 39A isoform X3. (488 aa)
TIMP1Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa)
TENT5DTerminal nucleotidyltransferase 5D. (390 aa)
DKC1Uncharacterized protein. (521 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
DND1DND microRNA-mediated repression inhibitor 1. (353 aa)
IL10RAInterleukin 10 receptor subunit alpha. (576 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (361 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (219 aa)
DAPL1Uncharacterized protein. (97 aa)
HTR2B5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (481 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
LARP1La ribonucleoprotein domain family member 1. (1101 aa)
FOXK2Forkhead box protein K2. (656 aa)
MEIOCMeiosis specific with coiled-coil domain. (940 aa)
BECN1Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] (461 aa)
STAT3Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. (718 aa)
PHF23PHD finger protein 23. (403 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (505 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
FEZ2Fasciculation and elongation protein zeta-2 isoform 2. (376 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (269 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (282 aa)
ZFP36Uncharacterized protein. (372 aa)
LEPRLeptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] (1165 aa)
HIPK2Homeodomain interacting protein kinase 2. (1208 aa)
THRAP3Thyroid hormone receptor-associated protein 3 isoform 1. (958 aa)
RASIP1Ras interacting protein 1. (967 aa)
MTMR8Myotubularin-related protein 8. (692 aa)
POLDIP2Polymerase delta-interacting protein 2 isoform 1. (368 aa)
LOC100625207USP domain-containing protein; Belongs to the peptidase C19 family. (2554 aa)
NOCTNocturnin. (427 aa)
DFFBDNAation factor subunit beta isoform 2. (341 aa)
TTC36Tetratricopeptide repeat domain 36. (188 aa)
DHX36DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv1. (1012 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
KDM4AUncharacterized protein. (1066 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (470 aa)
IGF2BP2Insulin like growth factor 2 mRNA binding protein 2. (592 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross- talk between glycosylation and phosphorylation or by affecting proteolytic processing. Probably by glycosylating [...] (1074 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
RBM10RNA binding motif protein 10. (931 aa)
DHX9ATP-dependent RNA helicase A. (1384 aa)
FMR1Fragile X mental retardation protein 1. (632 aa)
FUSFUS RNA binding protein. (518 aa)
LOC110258247Rab-GAP TBC domain-containing protein. (310 aa)
ANXA2Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (414 aa)
CHMP4ACharged multivesicular body protein 4A. (229 aa)
MT3Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa)
PKP3Plakophilin 3. (1145 aa)
DAPUncharacterized protein. (102 aa)
PKP1Plakophilin-1 isoform 1a. (727 aa)
MTM1Myotubularin isoform X3. (603 aa)
PHAXPhosphorylated adapter RNA export protein. (394 aa)
LOC110261265NTR domain-containing protein. (239 aa)
RBM24RRM domain-containing protein. (528 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform a. (825 aa)
UBQLN4Ubiquilin-4 isoform 1. (601 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (984 aa)
TENT2Poly(A) RNA polymerase GLD2 isoform X3. (484 aa)
TREM2Ig-like domain-containing protein. (248 aa)
RNF41E3 ubiquitin-protein ligase NRDP1 isoform 1. (317 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
DHX34DExH-box helicase 34. (1098 aa)
GIPC3GIPC PDZ domain containing family member 3. (314 aa)
TENT5BTerminal nucleotidyltransferase 5B. (426 aa)
A1CFAPOBEC1 complementation factor isoform 2. (595 aa)
TARDBPTAR DNA binding protein. (414 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (300 aa)
USP9XPutative ubiquitin carboxyl-terminal hydrolase FAF-X isoform X4; Belongs to the peptidase C19 family. (2554 aa)
RYBPRING1 and YY1 binding protein. (273 aa)
SLC11A1Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] (538 aa)
TBC1D14Rab-GAP TBC domain-containing protein. (465 aa)
STYXSerine/threonine/tyrosine interacting protein. (206 aa)
GDNFGlial cell line-derived neurotrophic factor isoform 1. (211 aa)
CSNK2A2Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. (350 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3. (586 aa)
PDCL3Phosducin-like protein 3. (240 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1175 aa)
TLK2Tousled like kinase 2. (766 aa)
TMEM39BTransmembrane protein 39B. (492 aa)
A0A287ANP8_PIGUncharacterized protein. (89 aa)
BMFBcl2 modifying factor. (183 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1171 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (910 aa)
ETFBKMTUncharacterized protein. (264 aa)
ADRA1AAlpha-1A adrenergic receptor isoform 1. (466 aa)
FHITFragile histidine triad diadenosine triphosphatase. (150 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
NRBP2Nuclear receptor binding protein 2. (599 aa)
ZCCHC17Zinc finger CCHC-type containing 17. (241 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa)
ANGEL2Protein angel homolog 2 isoform a. (544 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3646 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1613 aa)
FEZ1Fasciculation and elongation protein zeta 1. (420 aa)
SMCR8SMCR8-C9orf72 complex subunit. (935 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (487 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (233 aa)
AXIN2Axin-2. (843 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa)
LOC106510645Myotubularin-related protein 9. (543 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
HNRNPABUncharacterized protein. (345 aa)
CSDE1Cold shock domain containing E1. (851 aa)
SECISBP2Selenocysteine insertion sequence-binding protein 2 isoform 1. (848 aa)
DDRGK1DDRGK domain-containing protein 1. (312 aa)
WDR6WD repeat domain 6. (1120 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (395 aa)
GIPC2PDZ domain-containing protein GIPC2 isoform 1. (313 aa)
SORL1Sortilin related receptor 1. (2213 aa)
BAG5BAG family molecular chaperone regulator 5 isoform b. (447 aa)
RPL1160S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (192 aa)
RBM46RNA binding motif protein 46. (533 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (992 aa)
PLIN5Perilipin 5. (736 aa)
LOC100513415Uncharacterized protein. (449 aa)
APOC3Apolipoprotein C-III; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tigh [...] (199 aa)
UBXN1UBX domain protein 1. (310 aa)
TAF9Transcription initiation factor TFIID subunit 9. (265 aa)
MTMR9Myotubularin related protein 9. (576 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa)
A0A5G2QLC1_PIGUncharacterized protein. (477 aa)
HMOX1Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. (287 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (394 aa)
TRIM39E3 ubiquitin-protein ligase TRIM39 isoform 2. (488 aa)
TIMP2Uncharacterized protein. (257 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (398 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (541 aa)
ACACBBiotin carboxylation domain-containing protein. (229 aa)
C3H16orf96Uncharacterized protein. (928 aa)
HNRNPA0Heterogeneous nuclear ribonucleoprotein A0. (302 aa)
CLEC16AC-type lectin domain containing 16A. (1082 aa)
YBX1Y-box binding protein 1. (419 aa)
ENSAAlpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents (By similarity); Belongs to the endosulfine [...] (137 aa)
QSOX1Sulfhydryl oxidase. (742 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (664 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (485 aa)
DAZLDeleted in azoospermia-like protein. (295 aa)
BOLLBoule homolog, RNA binding protein. (430 aa)
PARNPoly(A)-specific ribonuclease. (715 aa)
GIPC1GIPC PDZ domain containing family member 1. (405 aa)
FOXK1Forkhead box K1. (762 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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