STRINGSTRING
MMP27 MMP27 MMP2 MMP2 VPS33B VPS33B P3H4 P3H4 COL1A1 COL1A1 ADAMTS3 ADAMTS3 PEPD PEPD PLOD3 PLOD3 VIPAS39 VIPAS39 RETREG3 RETREG3 HIF1A HIF1A MMP15 MMP15 MMP9 MMP9 SMPD3 SMPD3 MMP28 MMP28 MMP24 MMP24 MMP16 MMP16 TRAM2 TRAM2 SERPINH1 SERPINH1 RETREG1 RETREG1 TNXB TNXB RCN3 RCN3 MMP25 MMP25 MMP14 MMP14 ADAMTS2 ADAMTS2 P3H1 P3H1 MMP17 MMP17 MRC2 MRC2 RETREG2 RETREG2 COL1A2 COL1A2 MMP13 MMP13 MMP12 MMP12 MMP1 MMP1 MMP8 MMP8 MMP20 MMP20 MMP7 MMP7 P3H2 P3H2 CTSV CTSV CTSL CTSL MMP11 MMP11 P2RX7 P2RX7 CTSS CTSS COL5A1 COL5A1 MMP23B MMP23B P3H3 P3H3 MMP19 MMP19 TNS2 TNS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP27Matrix metallopeptidase 27. (511 aa)
MMP2Uncharacterized protein. (610 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (650 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (455 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1220 aa)
PEPDPeptidase D. (526 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa)
VIPAS39VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (539 aa)
RETREG3Reticulophagy regulator family member 3. (466 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
MMP15Matrix metallopeptidase 15. (712 aa)
MMP9Matrix metalloproteinase-9. (708 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
MMP28Matrix metallopeptidase 28. (521 aa)
MMP24Matrix metallopeptidase 24. (635 aa)
MMP16Matrix metalloproteinase-16. (607 aa)
TRAM2Translocation associated membrane protein 2. (392 aa)
SERPINH1SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)
RETREG1Reticulophagy regulator 1. (565 aa)
TNXBUncharacterized protein. (4137 aa)
RCN3Reticulocalbin 3. (335 aa)
MMP25Matrix metallopeptidase 25. (566 aa)
MMP14Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...] (606 aa)
ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif 2. (1204 aa)
P3H1Prolyl 3-hydroxylase 1 isoform 1. (698 aa)
MMP17Matrix metalloproteinase-17 preproprotein. (595 aa)
MRC2Mannose receptor C type 2. (1264 aa)
RETREG2Reticulophagy regulator family member 2. (542 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1135 aa)
MMP13Matrix metallopeptidase 13. (470 aa)
MMP12Macrophage metalloelastase preproprotein. (476 aa)
MMP1Stromelysin-1 preproprotein. (477 aa)
MMP8Matrix metallopeptidase 8. (468 aa)
MMP20Matrix metalloproteinase-20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation (By similarity). (483 aa)
MMP7ZnMc domain-containing protein. (267 aa)
P3H2Prolyl 3-hydroxylase 2 isoform a. (706 aa)
CTSVCathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (334 aa)
CTSLCathepsin L1 isoform 1 preproprotein; Belongs to the peptidase C1 family. (332 aa)
MMP11Stromelysin-3 preproprotein. (463 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (341 aa)
COL5A1Fibrillar collagen NC1 domain-containing protein. (1918 aa)
MMP23BMatrix metallopeptidase 23B. (391 aa)
P3H3Prolyl 3-hydroxylase 3. (727 aa)
MMP19Matrix metallopeptidase 19. (506 aa)
TNS2Tensin 2. (1350 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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