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| TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) | ||||
| HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (241 aa) | ||||
| NOD2 | Uncharacterized protein. (1013 aa) | ||||
| TNIP2 | TNFAIP3 interacting protein 2. (435 aa) | ||||
| RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (533 aa) | ||||
| IRAK1 | Interleukin 1 receptor associated kinase 1. (691 aa) | ||||
| PIK3AP1 | Phosphoinositide-3-kinase adaptor protein 1. (905 aa) | ||||