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NUP214 | Nucleoporin 214. (2016 aa) | ||||
SNUPN | Snurportin 1. (386 aa) | ||||
TPR | Translocated promoter region, nuclear basket protein. (2518 aa) | ||||
BCL3 | ANK_REP_REGION domain-containing protein. (453 aa) | ||||
NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (470 aa) | ||||
IPO13 | Importin-13. (963 aa) | ||||
KPNA3 | Importin subunit alpha; Functions in nuclear protein import. (521 aa) | ||||
KPNA2 | Importin subunit alpha; Functions in nuclear protein import. (529 aa) | ||||
PHB2 | Prohibitin. (299 aa) | ||||
CSE1L | Chromosome segregation 1 like. (973 aa) | ||||
HIKESHI | Heat shock protein nuclear import factor hikeshi. (197 aa) | ||||
RANBP2 | RAN binding protein 2. (3233 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (766 aa) | ||||
OSBPL8 | Oxysterol-binding protein; Belongs to the OSBP family. (889 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (601 aa) | ||||
TOR1AIP2 | Torsin 1A interacting protein 2. (531 aa) | ||||
FAM53C | Family with sequence similarity 53 member C. (389 aa) | ||||
SPG11 | SPG11 vesicle trafficking associated, spatacsin. (2467 aa) | ||||
TBRG1 | Transforming growth factor beta regulator 1. (411 aa) | ||||
KPNA1 | IBB domain-containing protein. (648 aa) | ||||
GCKR | Glucokinase regulator. (641 aa) | ||||
NUP62CL | Nucleoporin 62 C-terminal like. (183 aa) | ||||
CDK5 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa) | ||||
WRAP53 | WD repeat containing antisense to TP53. (539 aa) | ||||
CTDNEP1 | CTD nuclear envelope phosphatase 1. (244 aa) | ||||
NF1 | Neurofibromin 1. (2847 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa) | ||||
NUP50 | Nucleoporin 50. (440 aa) | ||||
IPO8 | Importin 8. (1037 aa) | ||||
LRRK2 | Uncharacterized protein. (2501 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (668 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (163 aa) | ||||
PML | Promyelocytic leukemia. (827 aa) | ||||
NFKBIA | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. (314 aa) | ||||
ARL2BP | ADP ribosylation factor like GTPase 2 binding protein. (175 aa) | ||||
DVL1 | Dishevelled segment polarity protein 1. (700 aa) | ||||
PARK7 | DJ-1 protein. (189 aa) | ||||
KPNA5 | Importin subunit alpha; Functions in nuclear protein import. (539 aa) | ||||
TRAF3IP2 | TRAF3 interacting protein 2. (574 aa) | ||||
PYGO1 | Pygopus family PHD finger 1. (419 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
SIX1 | Six homeobox 1. (284 aa) | ||||
RANBP6 | Ran-binding protein 6 isoform X1. (1105 aa) | ||||
XPA | XPA, DNA damage recognition and repair factor. (310 aa) | ||||
CIZ1 | CDKN1A interacting zinc finger protein 1. (758 aa) | ||||
RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa) | ||||
NXT1 | Nuclear transport factor 2 like export factor 1. (140 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (650 aa) | ||||
KPNA7 | Importin subunit alpha-8; Functions in nuclear protein import. (507 aa) | ||||
NOL8 | Nucleolar protein 8. (1123 aa) | ||||
SIX2 | SIX homeobox 2. (296 aa) | ||||
SUPT7L | STAGA complex 65 subunit gamma isoform b. (412 aa) | ||||
MSX1 | Homeobox domain-containing protein. (303 aa) | ||||
NUP54 | Nucleoporin 54. (564 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (523 aa) | ||||
FAM53B | Family with sequence similarity 53 member B. (430 aa) | ||||
TAF3 | TATA-box binding protein associated factor 3. (929 aa) | ||||
CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) | ||||
POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (584 aa) | ||||
CRY2 | Cryptochrome circadian regulator 2. (615 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) | ||||
ELAVL1 | ELAV-like protein; Belongs to the RRM elav family. (326 aa) | ||||
TNPO2 | Transportin 2. (913 aa) | ||||
CALR | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa) | ||||
LMNB1 | Lamin-B1 isoform 1; Belongs to the intermediate filament family. (586 aa) | ||||
TMCO6 | Transmembrane and coiled-coil domains 6. (517 aa) | ||||
UTP25 | UTP25 small subunit processor component. (760 aa) | ||||
WRN | WRN RecQ like helicase. (1466 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa) | ||||
GLI3 | GLI family zinc finger 3. (1586 aa) | ||||
F1SRM6_PIG | Uncharacterized protein. (954 aa) | ||||
NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (684 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) | ||||
STAT3 | Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa) | ||||
MORC3 | MORC family CW-type zinc finger 3. (939 aa) | ||||
SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa) | ||||
STK4 | Serine/threonine kinase 4. (502 aa) | ||||
IPO5 | Importin N-terminal domain-containing protein. (1127 aa) | ||||
A0A5G2R996_PIG | KASH domain-containing protein. (999 aa) | ||||
RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (222 aa) | ||||
IPO4 | Importin 4. (1153 aa) | ||||
RANGAP1 | Ran GTPase activating protein 1. (585 aa) | ||||
RPF2 | Ribosome production factor 2 homolog. (306 aa) | ||||
KPNB1 | Karyopherin subunit beta 1. (877 aa) | ||||
RPAIN | RPA interacting protein. (230 aa) | ||||
LOC102162368 | Uncharacterized protein. (313 aa) | ||||
IPO11 | Importin 11. (975 aa) | ||||
A0A5G2R752_PIG | DUF775 domain-containing protein. (196 aa) | ||||
A0A5G2QNQ5_PIG | Uncharacterized protein. (428 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1477 aa) | ||||
BBS4 | Uncharacterized protein. (826 aa) | ||||
NUP35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa) | ||||
PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (560 aa) | ||||
RRP7A | Ribosomal RNA processing 7 homolog A. (412 aa) | ||||
NUP153 | Nucleoporin 153. (1473 aa) | ||||
BANP | BEN domain-containing protein. (505 aa) | ||||
NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa) | ||||
SYNE1 | Uncharacterized protein. (1723 aa) | ||||
A0A5G2QD71_PIG | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (138 aa) | ||||
HEATR3 | HEAT repeat containing 3. (728 aa) | ||||
GPN3 | GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (323 aa) | ||||
POM121L2 | Uncharacterized protein. (451 aa) | ||||
PPP3R1 | Uncharacterized protein. (188 aa) | ||||
ING1 | Inhibitor of growth protein. (299 aa) | ||||
FGF9 | Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa) | ||||
AKIRIN2 | Akirin 2. (213 aa) | ||||
RPL11 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (192 aa) | ||||
KPNA6 | Importin subunit alpha; Functions in nuclear protein import. (578 aa) | ||||
A0A287BRG1_PIG | Uncharacterized protein. (210 aa) | ||||
TNPO3 | Transportin 3. (957 aa) | ||||
NUP188 | Nucleoporin 188. (1769 aa) | ||||
E2F3 | E2F transcription factor 3. (466 aa) | ||||
TOR1A | Torsin. (333 aa) | ||||
SQSTM1 | Sequestosome 1. (451 aa) | ||||
CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1. (114 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
TOR1AIP1 | Torsin 1A interacting protein 1. (590 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa) | ||||
TAF8 | TATA-box binding protein associated factor 8. (320 aa) | ||||
ARL2 | ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family. (211 aa) | ||||
IPO7 | Importin 7. (1068 aa) | ||||
NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) | ||||
SHISA4 | Shisa family member 4. (297 aa) | ||||
NUP62 | Nucleoporin 62. (478 aa) | ||||
RANGRF | Ran guanine nucleotide release factor isoform A. (182 aa) | ||||
FAM53A | Family with sequence similarity 53 member A. (359 aa) | ||||
NR5A1 | Steroidogenic factor 1; Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidy [...] (461 aa) | ||||
STK3 | Serine/threonine kinase 3. (542 aa) | ||||
LMNA | Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...] (704 aa) | ||||
TNPO1 | Transportin 1. (898 aa) | ||||
KPNA4 | Importin subunit alpha; Functions in nuclear protein import. (521 aa) | ||||
NXT2 | Nuclear transport factor 2 like export factor 2. (198 aa) | ||||
TOPORS | TOP1 binding arginine/serine rich protein. (1049 aa) | ||||
IPO9 | Importin 9. (1080 aa) | ||||
SUN1 | Sad1 and UNC84 domain containing 1. (848 aa) | ||||
PINX1 | PIN2/TERF1-interacting telomerase inhibitor 1 isoform 1. (313 aa) | ||||
PRICKLE1 | Prickle planar cell polarity protein 1. (856 aa) | ||||
RAP1GDS1 | Rap1 GTPase-GDP dissociation stimulator 1. (606 aa) | ||||
NUP133 | Nucleoporin 133. (1160 aa) | ||||
LMNB2 | Lamin B2; Belongs to the intermediate filament family. (742 aa) | ||||
POM121C | Uncharacterized protein. (1193 aa) | ||||
NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (797 aa) | ||||
ZBTB7A | Zinc finger and BTB domain containing 7A. (596 aa) | ||||
NUP155 | Nucleoporin 155. (1391 aa) | ||||
APPL1 | Adaptor protein phosphotyrosine interaction PH domain and leucine zipper containing 1. (708 aa) | ||||
ABCA7 | ATP binding cassette subfamily A member 7. (2206 aa) | ||||
NUTF2 | Nuclear transport factor 2. (103 aa) | ||||
EIF4ENIF1 | Eukaryotic translation initiation factor 4E nuclear import factor 1. (984 aa) | ||||
INTS13 | Protein asunder homolog isoform X1. (706 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U isoform a. (825 aa) | ||||
SIX4 | Homeobox domain-containing protein. (785 aa) | ||||
TXNIP | Thioredoxin-interacting protein; May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and co [...] (391 aa) | ||||
ABRA | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. (384 aa) | ||||
XPO1 | Exportin 1. (1071 aa) | ||||
NUP88 | Nucleoporin 88. (739 aa) | ||||
SYK | 40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...] (628 aa) | ||||
A0A286ZN03_PIG | Ribosomal_L5 domain-containing protein. (174 aa) | ||||
HHEX | Hematopoietically-expressed homeobox protein HHEX. (269 aa) |