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PDX1 PDX1 ANO1 ANO1 HIF1A HIF1A ADCY8 ADCY8 GPR27 GPR27 BAD BAD RFX6 RFX6 NR1H4 NR1H4 BAIAP3 BAIAP3 PPP3CB PPP3CB GPR68 GPR68 PLA2G6 PLA2G6 CFTR CFTR GCG GCG SRI SRI C2CD2L C2CD2L VSNL1 VSNL1 C1QTNF12 C1QTNF12 GPLD1 GPLD1 MPC2 MPC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDX1Homeobox domain-containing protein. (284 aa)
ANO1Anoctamin. (1043 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GPR27G protein-coupled receptor 27. (376 aa)
BADBCL2 associated agonist of cell death. (209 aa)
RFX6DNA-binding protein RFX6. (928 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (509 aa)
BAIAP3BAI1 associated protein 3. (1345 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (370 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1482 aa)
GCGGlicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa)
SRISorcin isoform A. (199 aa)
C2CD2LC2CD2 like. (707 aa)
VSNL1Visinin-like protein 1. (191 aa)
C1QTNF12C1q and TNF related 12. (308 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (906 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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