STRINGSTRING
DDX3X DDX3X MRPS2 MRPS2 EIF2A EIF2A EIF6 EIF6 DHX37 DHX37 RPF2 RPF2 A0A5G2QU22_PIG A0A5G2QU22_PIG NIP7 NIP7 RPL5 RPL5 A0A5G2QUR2_PIG A0A5G2QUR2_PIG MRPL22 MRPL22 C1QBP C1QBP PWP2 PWP2 A0A5G2QIT2_PIG A0A5G2QIT2_PIG RRP7A RRP7A XRCC5 XRCC5 A0A5G2QQ40_PIG A0A5G2QQ40_PIG RPSA RPSA RPS27 RPS27 MTERF3 MTERF3 A0A287BM86_PIG A0A287BM86_PIG RPL6 RPL6 ABT1 ABT1 A0A287AQP3_PIG A0A287AQP3_PIG RPS15 RPS15 RPS5 RPS5 NLE1 NLE1 RPLP0 RPLP0 DHX30 DHX30 MRM2 MRM2 RPL24 RPL24 RPS19 RPS19 RPL10 RPL10 MRPL20 MRPL20 A0A286ZPT4_PIG A0A286ZPT4_PIG MRTO4 MRTO4 RPL23A RPL23A MRPS11 MRPS11 MRPS7 MRPS7 NOP53 NOP53 LOC100623742 LOC100623742 RPS27L RPS27L DHX29 DHX29 DDX28 DDX28 ERAL1 ERAL1 F2Z522_PIG F2Z522_PIG FASTKD2 FASTKD2 MPV17L2 MPV17L2 CCDC105 CCDC105 PPAN PPAN RPS28 RPS28 CXHXorf66 CXHXorf66 SBDS SBDS PRKDC PRKDC RRS1 RRS1 MDN1 MDN1 EFL1 EFL1 NOP2 NOP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX3XATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
MRPS2Mitochondrial ribosomal protein S2. (410 aa)
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (591 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (246 aa)
DHX37DEAH-box helicase 37. (1186 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
A0A5G2QU22_PIGUncharacterized protein. (147 aa)
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (192 aa)
RPL560S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (299 aa)
A0A5G2QUR2_PIGUncharacterized protein. (102 aa)
MRPL22Mitochondrial ribosomal protein L22; Belongs to the universal ribosomal protein uL22 family. (257 aa)
C1QBPMitochondrial complement component 1 Q subcomponent-binding protein. (281 aa)
PWP2Uncharacterized protein. (1096 aa)
A0A5G2QIT2_PIGUncharacterized protein. (132 aa)
RRP7ARibosomal RNA processing 7 homolog A. (412 aa)
XRCC5X-ray repair cross complementing 5. (1011 aa)
A0A5G2QQ40_PIG40S ribosomal protein S27. (181 aa)
RPSA40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
RPS2740S ribosomal protein S27. (84 aa)
MTERF3Transcription termination factor 3, mitochondrial isoform 1. (445 aa)
A0A287BM86_PIGRibosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa)
RPL660S ribosomal protein L6; Component of the large ribosomal subunit. (271 aa)
ABT1Activator of basal transcription 1. (272 aa)
A0A287AQP3_PIGUncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (147 aa)
RPS1540S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
RPS540S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (240 aa)
NLE1Notchless homolog 1. (487 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (322 aa)
DHX30DExH-box helicase 30. (1194 aa)
MRM2FtsJ domain-containing protein. (246 aa)
RPL24Ribosomal protein L24. (217 aa)
RPS1940S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family. (196 aa)
RPL1060S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development. (329 aa)
MRPL2039S ribosomal protein L20, mitochondrial isoform 1; Belongs to the bacterial ribosomal protein bL20 family. (149 aa)
A0A286ZPT4_PIGUncharacterized protein. (71 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (272 aa)
RPL23ARibosomal protein L23a; Belongs to the universal ribosomal protein uL23 family. (156 aa)
MRPS11Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (196 aa)
MRPS728S ribosomal protein S7, mitochondrial. (242 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (470 aa)
LOC100623742Uncharacterized protein. (145 aa)
RPS27L40S ribosomal protein S27. (84 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1366 aa)
DDX28DEAD-box helicase 28. (540 aa)
ERAL1Era like 12S mitochondrial rRNA chaperone 1. (437 aa)
F2Z522_PIGUncharacterized protein. (116 aa)
FASTKD2FAST kinase domain-containing protein 2, mitochondrial. (689 aa)
MPV17L2MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (235 aa)
CCDC105Coiled-coil domain containing 105. (495 aa)
PPANSuppressor of SWI4 1 homolog isoform 1. (469 aa)
RPS2840S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa)
CXHXorf66Uncharacterized protein. (356 aa)
SBDSRibosome maturation protein SBDS. (250 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4136 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5596 aa)
EFL1Elongation factor like GTPase 1. (1120 aa)
NOP2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (822 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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