22 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	COL2A1	Collagen type II alpha 1 chain. (1486 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (292 aa)
	COL5A1	Fibrillar collagen NC1 domain-containing protein. (1918 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (341 aa)
	FBLN7	Fibulin 7. (569 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	HPSE	Heparanase isoform 1 preproprotein. (551 aa)
	NID1	Nidogen 1. (1309 aa)
	HPSE2	Inactive heparanase-2 isoform 1. (592 aa)
	HRG	Uncharacterized protein. (561 aa)
	AZU1	Azurocidin; This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin; Belongs to the peptidase S1 family. Elastase subfamily. (246 aa)
	COMP	Cartilage oligomeric matrix protein. (756 aa)
	PTPRF	Protein tyrosine phosphatase receptor type F. (1919 aa)
	GPNMB	Glycoprotein nmb. (565 aa)
	AGRN	Agrin. (2108 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1092 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (590 aa)
	TNC	Tenascin; Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha- V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity). Belongs to the tenascin family. (2420 aa)
	ADA2	Adenosine deaminase 2; Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity (By similarity). (509 aa)
	LRRTM3	Leucine-rich repeat transmembrane neuronal protein 3. (581 aa)
	BMPER	BMP binding endothelial regulator. (699 aa)
	SDCBP	Syndecan binding protein. (300 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	APOE	ENSSSCP00000034280	ENSSSCP00000003343	Agrin.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.615
AGRN	HPSE	ENSSSCP00000034280	ENSSSCP00000009850	Agrin.	Heparanase isoform 1 preproprotein.	0.418
AGRN	HPSE2	ENSSSCP00000034280	ENSSSCP00000011224	Agrin.	Inactive heparanase-2 isoform 1.	0.511
AGRN	NID1	ENSSSCP00000034280	ENSSSCP00000010826	Agrin.	Nidogen 1.	0.857
APOE	AGRN	ENSSSCP00000003343	ENSSSCP00000034280	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Agrin.	0.615
APOE	CTSS	ENSSSCP00000003343	ENSSSCP00000007089	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Cathepsin S; Belongs to the peptidase C1 family.	0.473
APOE	GPNMB	ENSSSCP00000003343	ENSSSCP00000031610	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Glycoprotein nmb.	0.560
AZU1	HRG	ENSSSCP00000014264	ENSSSCP00000012572	Azurocidin; This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin; Belongs to the peptidase S1 family. Elastase subfamily.	Uncharacterized protein.	0.632
COL2A1	COL5A1	ENSSSCP00000036099	ENSSSCP00000006161	Collagen type II alpha 1 chain.	Fibrillar collagen NC1 domain-containing protein.	0.737
COL2A1	COMP	ENSSSCP00000036099	ENSSSCP00000014796	Collagen type II alpha 1 chain.	Cartilage oligomeric matrix protein.	0.741
COL5A1	COL2A1	ENSSSCP00000006161	ENSSSCP00000036099	Fibrillar collagen NC1 domain-containing protein.	Collagen type II alpha 1 chain.	0.737
COMP	COL2A1	ENSSSCP00000014796	ENSSSCP00000036099	Cartilage oligomeric matrix protein.	Collagen type II alpha 1 chain.	0.741
CTSS	APOE	ENSSSCP00000007089	ENSSSCP00000003343	Cathepsin S; Belongs to the peptidase C1 family.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.473
GPNMB	APOE	ENSSSCP00000031610	ENSSSCP00000003343	Glycoprotein nmb.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.560
HPSE	AGRN	ENSSSCP00000009850	ENSSSCP00000034280	Heparanase isoform 1 preproprotein.	Agrin.	0.418
HPSE	HPSE2	ENSSSCP00000009850	ENSSSCP00000011224	Heparanase isoform 1 preproprotein.	Inactive heparanase-2 isoform 1.	0.904
HPSE2	AGRN	ENSSSCP00000011224	ENSSSCP00000034280	Inactive heparanase-2 isoform 1.	Agrin.	0.511
HPSE2	HPSE	ENSSSCP00000011224	ENSSSCP00000009850	Inactive heparanase-2 isoform 1.	Heparanase isoform 1 preproprotein.	0.904
HRG	AZU1	ENSSSCP00000012572	ENSSSCP00000014264	Uncharacterized protein.	Azurocidin; This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin; Belongs to the peptidase S1 family. Elastase subfamily.	0.632
NID1	AGRN	ENSSSCP00000010826	ENSSSCP00000034280	Nidogen 1.	Agrin.	0.857