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DPP4 | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] (833 aa) | ||||
CDH13 | Uncharacterized protein. (771 aa) | ||||
VSTM4 | V-set and transmembrane domain containing 4. (382 aa) | ||||
PXN | Uncharacterized protein. (1072 aa) | ||||
ADGRA2 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1336 aa) | ||||
PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5. (1078 aa) | ||||
ROBO1 | Roundabout guidance receptor 1. (1687 aa) | ||||
NRP1 | Neuropilin; Belongs to the neuropilin family. (924 aa) | ||||
PLXND1 | Plexin D1. (1926 aa) | ||||
CCBE1 | Collagen and calcium binding EGF domains 1. (407 aa) | ||||
GIPC1 | GIPC PDZ domain containing family member 1. (405 aa) | ||||
AMOT | Angiomotin isoform X1. (1088 aa) | ||||
FAP | Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa) | ||||
S100A2 | S100 calcium binding protein A2. (170 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1360 aa) | ||||
S100Z | Protein S100; Belongs to the S-100 family. (99 aa) | ||||
LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) | ||||
CLEC14A | C-type lectin domain family 14 member A. (493 aa) | ||||
LGALS12 | Galectin. (330 aa) | ||||
VHL | Von Hippel-Lindau disease tumor suppressor isoform 1. (205 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB- containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. (509 aa) | ||||
STARD13 | Uncharacterized protein. (541 aa) | ||||
ADTRP | Androgen dependent TFPI regulating protein. (230 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (906 aa) | ||||
SRF | Serum response factor. (512 aa) | ||||
CCN3 | Cellular communication network factor 3. (398 aa) | ||||
RAB13 | Uncharacterized protein. (203 aa) | ||||
EPHB4 | EPH receptor B4. (935 aa) | ||||
SLIT2 | Slit guidance ligand 2. (1542 aa) | ||||
FSTL1 | Follistatin like 1. (307 aa) | ||||
GIPC2 | PDZ domain-containing protein GIPC2 isoform 1. (313 aa) | ||||
CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (451 aa) | ||||
LGALS8 | Galectin. (368 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1146 aa) | ||||
EGR3 | Early growth response protein 3 isoform 1. (387 aa) | ||||
LOC100511937 | Uncharacterized protein. (532 aa) | ||||
MMRN2 | Multimerin 2. (931 aa) | ||||
CORO1B | Coronin; Belongs to the WD repeat coronin family. (496 aa) | ||||
CLN3 | Battenin. (414 aa) | ||||
NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity). (1239 aa) | ||||
CDH5 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] (782 aa) | ||||
SOX18 | SRY-box transcription factor 18. (389 aa) | ||||
RHOA | Transforming protein RhoA isoform 1. (193 aa) | ||||
A0A287ANG8_PIG | Protein kinase domain-containing protein. (183 aa) | ||||
NR4A1 | Nuclear receptor subfamily 4 group A member 1 isoform 2. (598 aa) | ||||
LOXL2 | Lysyl oxidase like 2. (758 aa) | ||||
CXCL13 | C-X-C motif chemokine. (111 aa) | ||||
GIPC3 | GIPC PDZ domain containing family member 3. (314 aa) | ||||
EDN2 | Endothelin 2. (180 aa) | ||||
GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) | ||||
EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) | ||||
EFNB2 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (335 aa) | ||||
PAXIP1 | PAX interacting protein 1. (1030 aa) | ||||
PTP4A3 | Protein tyrosine phosphatase 4A3. (173 aa) | ||||
PRKX | Uncharacterized protein; Belongs to the protein kinase superfamily. (358 aa) | ||||
APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa) | ||||
TGFBR1 | TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] (560 aa) | ||||
ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa) |