STRINGSTRING
ITGA1 ITGA1 EXT1 EXT1 TRIM55 TRIM55 SELE SELE ITGAL ITGAL CRKL CRKL CD99L2 CD99L2 PRTN3 PRTN3 ADD2 ADD2 I3L9Z6_PIG I3L9Z6_PIG FER FER K7GLG1_PIG K7GLG1_PIG ITGB1 ITGB1 JAM2 JAM2 CRK CRK MADCAM1 MADCAM1 XG XG A0A287A3F2_PIG A0A287A3F2_PIG A0A287AB18_PIG A0A287AB18_PIG LOC110257335 LOC110257335 ITGA4 ITGA4 A0A287AEV6_PIG A0A287AEV6_PIG ITGB7 ITGB7 PECAM1 PECAM1 JAML JAML PODXL2 PODXL2 XG-2 XG-2 GCNT1 GCNT1 ROCK1 ROCK1 SELL SELL F11R F11R SELP SELP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1175 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
TRIM55Tripartite motif containing 55. (540 aa)
SELEE-selectin; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis (By similarity). Belongs to the selectin/LECAM family. (484 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1235 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CD99L2CD99 molecule like 2. (213 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (268 aa)
ADD2Adducin 2. (725 aa)
I3L9Z6_PIGUncharacterized protein. (335 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
K7GLG1_PIGUncharacterized protein. (449 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa)
JAM2Junctional adhesion molecule 2. (307 aa)
CRKCRK proto-oncogene, adaptor protein. (385 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1 isoform a. (390 aa)
XGXg glycoprotein (Xg blood group). (210 aa)
A0A287A3F2_PIGUncharacterized protein. (100 aa)
A0A287AB18_PIGUncharacterized protein. (385 aa)
LOC110257335Golgi phosphoprotein 3 (Coat-protein). (298 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1055 aa)
A0A287AEV6_PIGUncharacterized protein. (213 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (882 aa)
PECAM1Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] (740 aa)
JAMLJunction adhesion molecule like. (410 aa)
PODXL2Podocalyxin like 2. (691 aa)
XG-2Uncharacterized protein. (194 aa)
GCNT1Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase. (428 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
SELLSelectin L. (399 aa)
F11RUncharacterized protein. (347 aa)
SELPUncharacterized protein. (671 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.