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| | POU4F1 | POU domain protein. (421 aa) |
| | ANKRD54 | Ankyrin repeat domain 54. (397 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (829 aa) |
| | IL17A | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. Belongs to the IL-17 family. (153 aa) |
| | WDR61 | WD repeat-containing protein 61 isoform a. (305 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | CIB1 | Calcium and integrin-binding protein 1 isoform b. (191 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. (314 aa) |
| | RCOR1 | REST corepressor 1. (487 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | FOXO3 | Forkhead box protein O3 isoform X1. (672 aa) |
| | FBN1 | Fibrillin-1; [Fibrillin-1]: Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus [...] (2871 aa) |
| | DCSTAMP | Dendrocyte expressed seven transmembrane protein. (487 aa) |
| | KLF10 | Kruppel-like factor 10. (480 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools; Belongs to the HAX1 family. (284 aa) |
| | PIAS3 | Protein inhibitor of activated STAT 3. (628 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa) |
| | RBM15 | RNA binding motif protein 15. (1006 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa) |
| | FAM210B | Family with sequence similarity 210 member B. (239 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (523 aa) |
| | RB1 | RB transcriptional corepressor 1. (938 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | HMGB2 | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] (210 aa) |
| | TESC | Calcineurin B homologous protein 3 isoform 1. (240 aa) |
| | PLA2G3 | Phospholipase A2 group III. (501 aa) |
| | ABCB10 | ATP binding cassette subfamily B member 10. (725 aa) |
| | LDB1 | LID domain-containing protein. (411 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | P4HTM | Prolyl 4-hydroxylase, transmembrane. (496 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | TFE3 | Transcription factor binding to IGHM enhancer 3. (575 aa) |
| | GPR137 | G protein-coupled receptor 137. (423 aa) |
| | FSHB | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa) |
| | CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1169 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa) |
| | LOX | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family. (419 aa) |
| | PPARGC1B | Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1. (1028 aa) |
| | HOXA5 | Homeobox domain-containing protein. (381 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa) |
| | STAT3 | Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa) |
| | STAT5A | Signal transducer and activator of transcription 5A; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation (By similarity). (799 aa) |
| | STAT5B | Signal transducer and activator of transcription 5B; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. (787 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa) |
| | HOXB8 | Homeobox protein Hox-B8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (242 aa) |
| | NF1 | Neurofibromin 1. (2847 aa) |
| | CD4 | CD4 molecule. (494 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | TNFAIP6 | Uncharacterized protein. (277 aa) |
| | PITHD1 | PITH domain containing 1. (211 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) |
| | OCSTAMP | Osteoclast stimulatory transmembrane protein. (503 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (779 aa) |
| | ZFP36 | Uncharacterized protein. (372 aa) |
| | GATA1 | Erythroid transcription factor. (412 aa) |
| | THPO | Thrombopoietin; Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. (477 aa) |
| | TMEM178A | Transmembrane protein 178A. (297 aa) |
| | HOXA7 | Homeobox A7. (234 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (766 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (729 aa) |
| | CASP8 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. (486 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (520 aa) |
| | LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa) |
| | CD101 | CD101 molecule. (1018 aa) |
| | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (1045 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | CTNNB1 | Catenin beta 1. (808 aa) |
| | RBFOX2 | RNA binding fox-1 homolog 2. (578 aa) |
| | RARG | Retinoic acid receptor gamma. (554 aa) |
| | SMAP1 | Small ArfGAP 1. (474 aa) |
| | STAT1 | Signal transducer and activator of transcription 1; Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to [...] (856 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (429 aa) |
| | TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (541 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | C1QC | Complement C1q subcomponent subunit C isoform 1. (245 aa) |
| | HSF1 | Heat shock transcription factor 1. (590 aa) |
| | APCS | Serum amyloid P-component; Belongs to the pentraxin family. (224 aa) |
| | RARA | Retinoic acid receptor alpha isoform X1. (462 aa) |
| | MTURN | Maturin, neural progenitor differentiation regulator homolog. (135 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa) |
| | ZNF16 | Zinc finger protein 16. (576 aa) |
| | MEIS2 | Meis homeobox 2. (477 aa) |
| | LIF | Leukemia inhibitory factor isoform X1. (202 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa) |
| | TREM2 | Ig-like domain-containing protein. (248 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform 1. (317 aa) |
| | EVI2B | Ecotropic viral integration site 2B. (459 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa) |
| | GPR55 | G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | IL23A | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] (193 aa) |
| | RHEX | Regulator of hemoglobinization and erythroid cell expansion. (171 aa) |
| | MEIS1 | Homeobox protein Meis1. (465 aa) |
| | IL34 | Interleukin 34. (243 aa) |
| | ISG15 | Ubiquitin-like modifier. (167 aa) |
| | BRD1 | Bromodomain containing 1. (1187 aa) |
| | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1199 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) |
| | SCIN | Adseverin; Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Severing activity is inhibited by phosphatidylinositol 4,5-bis- phosphate (PIP2) (By similarity). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskel [...] (715 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (200 aa) |
| | TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa) |
| | FOXP1 | Forkhead box P1. (692 aa) |
| | GABPA | GA binding protein transcription factor subunit alpha. (454 aa) |
| | LEO1 | LEO1 homolog, Paf1/RNA polymerase II complex component. (668 aa) |
| | FAXDC2 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (338 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (324 aa) |
| | TMEM64 | Transmembrane protein 64. (387 aa) |
| | ADIPOQ | C1q domain-containing protein. (332 aa) |
| | FSTL3 | Follistatin-related protein 3. (262 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (965 aa) |
| | NDFIP1 | Uncharacterized protein. (254 aa) |
| | CNOT4 | CCR4-NOT transcription complex subunit 4. (710 aa) |
| | PTX4 | Pentraxin 4. (477 aa) |
| | CD74 | Thyroglobulin type-1 domain-containing protein. (347 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (824 aa) |
| | ZBTB46 | Zinc finger and BTB domain-containing protein 46. (589 aa) |
| | RASSF2 | Ras association domain-containing protein 2 isoform X2. (326 aa) |
| | MITF | Microphthalmia-associated transcription factor isoform 1. (520 aa) |
| | INHBA | Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (424 aa) |
| | GPR137B | G protein-coupled receptor 137B. (415 aa) |
| | PRXL2A | Peroxiredoxin like 2A. (229 aa) |
| | UBASH3B | Ubiquitin associated and SH3 domain containing B. (638 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (650 aa) |
| | TOB2 | Protein Tob2 isoform X1. (353 aa) |
| | SLC9B2 | Solute carrier family 9 member B2. (537 aa) |
| | LRRC17 | Leucine rich repeat containing 17. (438 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (447 aa) |
| | CSF1 | Colony stimulating factor 1. (656 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (668 aa) |
| | PRMT1 | Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (383 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (348 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (621 aa) |
| | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (560 aa) |
| | A0A5G2QKY7_PIG | Kinase; Belongs to the inositol phosphokinase (IPK) family. (363 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1128 aa) |
| | CSF3 | Granulocyte colony-stimulating factor; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes (By similarity); Belongs to the IL-6 superfamily. (204 aa) |
| | CSF3R | Granulocyte colony-stimulating factor receptor. (848 aa) |
| | GPR171 | Putative G-protein coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. (319 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (712 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (246 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (525 aa) |
| | IL20 | Interleukin 20. (175 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (547 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa) |
