STRINGSTRING
DCSTAMP DCSTAMP SPP1 SPP1 TNFSF11 TNFSF11 FSHB FSHB PPARGC1B PPARGC1B PLEKHM1 PLEKHM1 TNFRSF11A TNFRSF11A ADAM8 ADAM8 SYK SYK TMEM64 TMEM64 FCGR3A FCGR3A LTBP3 LTBP3 DEF8 DEF8 TF-2 TF-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCSTAMPDendrocyte expressed seven transmembrane protein. (487 aa)
SPP1Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. (303 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa)
FSHBFollitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1. (1028 aa)
PLEKHM1Pleckstrin homology domain-containing family M member 1 isoform X1. (1048 aa)
TNFRSF11ATNF receptor superfamily member 11a. (629 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8. (835 aa)
SYK40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...] (628 aa)
TMEM64Transmembrane protein 64. (387 aa)
FCGR3ALow affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. (259 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1332 aa)
DEF8Differentially expressed in FDCP 8 homolog. (522 aa)
TF-2Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (702 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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