43 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CPT1B	Carnitine O-palmitoyltransferase 1, muscle isoform. (807 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (906 aa)
	LPCAT4	Lysophosphatidylcholine acyltransferase 4. (539 aa)
	LPCAT2	Lysophosphatidylcholine acyltransferase 2. (543 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (458 aa)
	MBOAT7	Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
	GPAT4	PlsC domain-containing protein. (457 aa)
	PLA2G3	Phospholipase A2 group III. (501 aa)
	CHKA	Choline kinase alpha. (565 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (470 aa)
	PNPLA8	Calcium-independent phospholipase A2-gamma isoform 1. (783 aa)
	LPCAT1	Lysophosphatidylcholine acyltransferase 1. (534 aa)
	MBOAT2	Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family. (520 aa)
	GDPD3	Glycerophosphodiester phosphodiesterase domain containing 3. (305 aa)
	LCAT	Phosphatidylcholine-sterol acyltransferase. (471 aa)
	PCYT1B	Phosphate cytidylyltransferase 1, choline, beta. (368 aa)
	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X3. (1006 aa)
	PLA2G2F	Phospholipase A(2). (302 aa)
	CEPT1	Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (447 aa)
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa)
	PNPLA6	Patatin like phospholipase domain containing 6. (1363 aa)
	PLA2G6	Phospholipase A2 group VI. (806 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	FABP5	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (235 aa)
	DHRS7B	Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)
	ABHD3	Abhydrolase domain containing 3. (417 aa)
	PLA2G10	Phospholipase A(2). (188 aa)
	PLA2G2E	Phospholipase A(2). (142 aa)
	PON1	Paraoxonase 1. (355 aa)
	SLC27A1	Solute carrier family 27 (Fatty acid transporter), member 1. (646 aa)
	DBI	Acyl-CoA-binding protein; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor; Belongs to the ACBP family. (88 aa)
	CHPT1	Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (406 aa)
	PLA2G7	Platelet-activating factor acetylhydrolase. (441 aa)
	APOA4	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. (392 aa)
	PLA2G4A	Phospholipase A2. (758 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (489 aa)
	PCYT1A	Phosphate cytidylyltransferase 1, choline, alpha. (468 aa)
	LPCAT3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
	PNPLA7	Patatin like phospholipase domain containing 7. (1413 aa)
	PEMT	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (267 aa)
	APOA2	Apolipoprotein A-II preproprotein. (100 aa)
	A0A5G2R3N8_PIG	Uncharacterized protein. (135 aa)
	PLA2G1B	Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family. (146 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD3	PNPLA8	ENSSSCP00000037949	ENSSSCP00000016377	Abhydrolase domain containing 3.	Calcium-independent phospholipase A2-gamma isoform 1.	0.499
APOA1	APOA2	ENSSSCP00000033805	ENSSSCP00000069906	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein A-II preproprotein.	0.992
APOA1	APOA4	ENSSSCP00000033805	ENSSSCP00000057231	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.	0.861
APOA1	DBI	ENSSSCP00000033805	ENSSSCP00000049861	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Acyl-CoA-binding protein; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor; Belongs to the ACBP family.	0.466
APOA1	LCAT	ENSSSCP00000033805	ENSSSCP00000024443	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Phosphatidylcholine-sterol acyltransferase.	0.981
APOA1	PON1	ENSSSCP00000033805	ENSSSCP00000048590	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Paraoxonase 1.	0.752
APOA2	APOA1	ENSSSCP00000069906	ENSSSCP00000033805	Apolipoprotein A-II preproprotein.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.992
APOA2	APOA4	ENSSSCP00000069906	ENSSSCP00000057231	Apolipoprotein A-II preproprotein.	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.	0.961
APOA2	GPLD1	ENSSSCP00000069906	ENSSSCP00000001160	Apolipoprotein A-II preproprotein.	Glycosylphosphatidylinositol specific phospholipase D1.	0.497
APOA2	LCAT	ENSSSCP00000069906	ENSSSCP00000024443	Apolipoprotein A-II preproprotein.	Phosphatidylcholine-sterol acyltransferase.	0.844
APOA2	PON1	ENSSSCP00000069906	ENSSSCP00000048590	Apolipoprotein A-II preproprotein.	Paraoxonase 1.	0.763
APOA4	APOA1	ENSSSCP00000057231	ENSSSCP00000033805	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.861
APOA4	APOA2	ENSSSCP00000057231	ENSSSCP00000069906	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.	Apolipoprotein A-II preproprotein.	0.961
APOA4	LCAT	ENSSSCP00000057231	ENSSSCP00000024443	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.	Phosphatidylcholine-sterol acyltransferase.	0.813
APOA4	PON1	ENSSSCP00000057231	ENSSSCP00000048590	Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.	Paraoxonase 1.	0.513
CEPT1	CHKA	ENSSSCP00000032814	ENSSSCP00000013705	Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Choline kinase alpha.	0.504
CEPT1	CHPT1	ENSSSCP00000032814	ENSSSCP00000052534	Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.901
CEPT1	GPAT4	ENSSSCP00000032814	ENSSSCP00000007481	Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	PlsC domain-containing protein.	0.481
CEPT1	LPCAT1	ENSSSCP00000032814	ENSSSCP00000018133	Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Lysophosphatidylcholine acyltransferase 1.	0.916
CEPT1	LPCAT2	ENSSSCP00000032814	ENSSSCP00000003048	Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Lysophosphatidylcholine acyltransferase 2.	0.475