STRINGSTRING
DDX17 DDX17 CELF2 CELF2 NOVA2 NOVA2 RBM24 RBM24 NSRP1 NSRP1 REST REST LOC100526209 LOC100526209 TRA2A TRA2A CEP57L1 CEP57L1 RBFOX1 RBFOX1 CELF6 CELF6 PCBP4 PCBP4 LOC102161120 LOC102161120 C1QBP C1QBP NCBP1 NCBP1 PTBP1 PTBP1 JMJD6 JMJD6 RAVER2 RAVER2 LOC110258135 LOC110258135 SRSF4 SRSF4 RBM25 RBM25 DDX5 DDX5 ZC3H10 ZC3H10 SON SON CELF3 CELF3 PRDX6 PRDX6 RBM39 RBM39 QKI QKI CELF1 CELF1 YTHDC1 YTHDC1 PUF60 PUF60 CELF4 CELF4 SRRM1 SRRM1 SRSF12 SRSF12 SRSF7 SRSF7 RBM11 RBM11 SLC39A5 SLC39A5 DYRK1A DYRK1A MBNL1 MBNL1 U2AF2 U2AF2 CELF5 CELF5 NOVA1 NOVA1 SRSF2 SRSF2 ZBTB7A ZBTB7A WTAP WTAP KHDRBS2 KHDRBS2 RBM42 RBM42 RBM23 RBM23 HNRNPU HNRNPU SRSF3 SRSF3 SF3B4 SF3B4 RBM15 RBM15 RBM38 RBM38 MBNL2 MBNL2 SRRM4 SRRM4 HMX2 HMX2 SMU1 SMU1 RBM15B RBM15B PRPF19 PRPF19 MYOD1 MYOD1 NUP98 NUP98 NCL NCL EIF4A3 EIF4A3 FXR2 FXR2 FAM172A FAM172A SNW1 SNW1 TRA2B TRA2B FXR1 FXR1 RBM8A RBM8A THRAP3 THRAP3 KHDRBS1 KHDRBS1 HNRNPK HNRNPK TIA1 TIA1 RBM7 RBM7 PRR3 PRR3 RBM10 RBM10 RBMX RBMX KHDRBS3 KHDRBS3 MBNL3 MBNL3 FMR1 FMR1 LOC110257929 LOC110257929 DAZAP1 DAZAP1 RBM5 RBM5 RBFOX2 RBFOX2 RBFOX3 RBFOX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (588 aa)
CELF2Uncharacterized protein. (542 aa)
NOVA2NOVA alternative splicing regulator 2. (492 aa)
RBM24RRM domain-containing protein. (528 aa)
NSRP1Nuclear speckle splicing regulatory protein 1. (614 aa)
RESTRE1 silencing transcription factor. (1108 aa)
LOC100526209Uncharacterized protein. (788 aa)
TRA2ATransformer 2 alpha homolog. (294 aa)
CEP57L1Centrosomal protein 57 like 1. (630 aa)
RBFOX1RNA binding fox-1 homolog 1. (577 aa)
CELF6Uncharacterized protein. (610 aa)
PCBP4Poly(rC) binding protein 4. (404 aa)
LOC102161120Uncharacterized protein. (392 aa)
C1QBPMitochondrial complement component 1 Q subcomponent-binding protein. (281 aa)
NCBP1Nuclear cap binding protein subunit 1. (1117 aa)
PTBP1Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). (647 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa)
RAVER2Ribonucleoprotein, PTB binding 2. (691 aa)
LOC110258135Uncharacterized protein. (177 aa)
SRSF4Serine and arginine rich splicing factor 4. (489 aa)
RBM25RNA binding motif protein 25. (862 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
ZC3H10Zinc finger CCCH-type containing 10. (435 aa)
SONSON DNA binding protein. (2447 aa)
CELF3CUGBP Elav-like family member 3. (495 aa)
PRDX6Peroxiredoxin-6; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role [...] (224 aa)
RBM39RNA-binding protein 39 isoform a. (530 aa)
QKIProtein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). (338 aa)
CELF1CUGBP Elav-like family member 1. (551 aa)
YTHDC1YTH domain containing 1. (743 aa)
PUF60Poly(U)-binding-splicing factor PUF60 isoform a. (587 aa)
CELF4CUGBP Elav-like family member 4. (545 aa)
SRRM1Serine and arginine repetitive matrix 1. (968 aa)
SRSF12Serine and arginine rich splicing factor 12. (262 aa)
SRSF7Serine/arginine-rich splicing factor 7 isoform 1. (238 aa)
RBM11Splicing regulator RBM11 isoform X1. (237 aa)
SLC39A5Solute carrier family 39 member 5. (554 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (764 aa)
MBNL1Muscleblind like splicing regulator 1. (436 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa)
CELF5CUGBP Elav-like family member 5 isoform X1. (485 aa)
NOVA1NOVA alternative splicing regulator 1. (487 aa)
SRSF2Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5 [...] (221 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (596 aa)
WTAPUncharacterized protein. (649 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (349 aa)
RBM42RNA binding motif protein 42. (477 aa)
RBM23RNA binding motif protein 23. (429 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform a. (825 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
RBM15RNA binding motif protein 15. (1006 aa)
RBM38RNA-binding region (RNP1, RRM) containing 1. (239 aa)
MBNL2Muscleblind like splicing regulator 2. (391 aa)
SRRM4Serine/arginine repetitive matrix 4. (611 aa)
HMX2H6 family homeobox 2. (281 aa)
SMU1Uncharacterized protein. (511 aa)
RBM15BRNA binding motif protein 15B. (854 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
MYOD1Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa)
NUP98Nucleoporin 98. (1753 aa)
NCLZinc finger protein Pegasus. (724 aa)
EIF4A3Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] (488 aa)
FXR2FMR1 autosomal homolog 2. (667 aa)
FAM172AFamily with sequence similarity 172 member A. (416 aa)
SNW1SNW domain-containing protein 1 isoform 2. (536 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X1. (677 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
THRAP3Thyroid hormone receptor-associated protein 3 isoform 1. (958 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
HNRNPKUncharacterized protein. (464 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
RBM7RNA-binding protein 7 isoform b. (265 aa)
PRR3Proline-rich protein 3. (222 aa)
RBM10RNA binding motif protein 10. (931 aa)
RBMXRNA binding motif protein X-linked. (408 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (352 aa)
MBNL3Muscleblind like splicing regulator 3. (369 aa)
FMR1Fragile X mental retardation protein 1. (632 aa)
LOC110257929RRM domain-containing protein. (307 aa)
DAZAP1DAZ associated protein 1. (417 aa)
RBM5RNA binding motif protein 5. (893 aa)
RBFOX2RNA binding fox-1 homolog 2. (578 aa)
RBFOX3RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (371 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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