15 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (527 aa)
	RXRA	Retinoid X receptor alpha. (701 aa)
	RXRG	Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). (463 aa)
	ESRRG	Estrogen-related receptor gamma isoform 1. (458 aa)
	ACTN4	Actinin alpha 4. (1160 aa)
	A0A287A514_PIG	NR LBD domain-containing protein. (88 aa)
	RARA	Retinoic acid receptor alpha isoform X1. (462 aa)
	RARG	Retinoic acid receptor gamma. (554 aa)
	PTF1A	Pancreas associated transcription factor 1a. (328 aa)
	SNW1	SNW domain-containing protein 1 isoform 2. (536 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	PML	Promyelocytic leukemia. (827 aa)
	RXRB	Retinoid X receptor beta. (536 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	CYP26B1	ENSSSCP00000074195	ENSSSCP00000008873	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.941
CYP26B1	ALDH1A2	ENSSSCP00000008873	ENSSSCP00000074195	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	0.941
CYP26B1	RARG	ENSSSCP00000008873	ENSSSCP00000032642	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Retinoic acid receptor gamma.	0.413
ESRRG	PPARG	ENSSSCP00000053415	ENSSSCP00000012339	Estrogen-related receptor gamma isoform 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.474
PML	RARA	ENSSSCP00000002091	ENSSSCP00000035518	Promyelocytic leukemia.	Retinoic acid receptor alpha isoform X1.	0.963
PML	RARG	ENSSSCP00000002091	ENSSSCP00000032642	Promyelocytic leukemia.	Retinoic acid receptor gamma.	0.413
PPARG	ESRRG	ENSSSCP00000012339	ENSSSCP00000053415	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Estrogen-related receptor gamma isoform 1.	0.474
PPARG	RARA	ENSSSCP00000012339	ENSSSCP00000035518	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoic acid receptor alpha isoform X1.	0.557
PPARG	RARG	ENSSSCP00000012339	ENSSSCP00000032642	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoic acid receptor gamma.	0.510
PPARG	RXRA	ENSSSCP00000012339	ENSSSCP00000070850	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoid X receptor alpha.	0.995
PPARG	RXRB	ENSSSCP00000012339	ENSSSCP00000001600	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoid X receptor beta.	0.961
PPARG	RXRG	ENSSSCP00000012339	ENSSSCP00000057363	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).	0.977
RARA	PML	ENSSSCP00000035518	ENSSSCP00000002091	Retinoic acid receptor alpha isoform X1.	Promyelocytic leukemia.	0.963
RARA	PPARG	ENSSSCP00000035518	ENSSSCP00000012339	Retinoic acid receptor alpha isoform X1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.557
RARA	RARG	ENSSSCP00000035518	ENSSSCP00000032642	Retinoic acid receptor alpha isoform X1.	Retinoic acid receptor gamma.	0.414
RARA	RXRA	ENSSSCP00000035518	ENSSSCP00000070850	Retinoic acid receptor alpha isoform X1.	Retinoid X receptor alpha.	0.982
RARA	RXRB	ENSSSCP00000035518	ENSSSCP00000001600	Retinoic acid receptor alpha isoform X1.	Retinoid X receptor beta.	0.895
RARA	RXRG	ENSSSCP00000035518	ENSSSCP00000057363	Retinoic acid receptor alpha isoform X1.	Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).	0.912
RARG	CYP26B1	ENSSSCP00000032642	ENSSSCP00000008873	Retinoic acid receptor gamma.	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.413
RARG	PML	ENSSSCP00000032642	ENSSSCP00000002091	Retinoic acid receptor gamma.	Promyelocytic leukemia.	0.413