STRINGSTRING
PDGFRB PDGFRB COL1A2 COL1A2 PDGFB PDGFB COL5A1 COL5A1 COL2A1 COL2A1 COL1A1 COL1A1 COL3A1 COL3A1 COL6A1 COL6A1 A0A5G2QUL4_PIG A0A5G2QUL4_PIG PDGFRA PDGFRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1181 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1135 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
COL5A1Fibrillar collagen NC1 domain-containing protein. (1918 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1471 aa)
COL6A1Collagen type VI alpha 1 chain. (1028 aa)
A0A5G2QUL4_PIGUncharacterized protein. (536 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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