STRINGSTRING
SH3GL1 SH3GL1 ITSN1 ITSN1 NOSTRIN NOSTRIN DNM2 DNM2 A0A287AZ68_PIG A0A287AZ68_PIG CANX CANX DENND1A DENND1A FCHO2 FCHO2 PACSIN1 PACSIN1 LOC100624109-2 LOC100624109-2 ACTG1 ACTG1 A0A287AA37_PIG A0A287AA37_PIG NLGN3 NLGN3 DNM3 DNM3 SYNJ1 SYNJ1 ACTB ACTB SNAP91 SNAP91 DNAJC6 DNAJC6 STON2 STON2 SYNPR SYNPR LOC100624109 LOC100624109 TBC1D24 TBC1D24 SNCA SNCA SYT5 SYT5 DNM1 DNM1 SYT8 SYT8 AMPH AMPH SYNJ2 SYNJ2 PICALM PICALM SNCB SNCB SNCG SNCG SYP SYP NLGN1 NLGN1 SYT2 SYT2 STX1A STX1A SH3GL2 SH3GL2 LRRC1 LRRC1 SYT1 SYT1 VAMP2 VAMP2 OPHN1 OPHN1 SH3GL3 SH3GL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (405 aa)
ITSN1Intersectin 1. (1485 aa)
NOSTRINNitric oxide synthase trafficking. (504 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (877 aa)
A0A287AZ68_PIGPDZ domain-containing protein. (909 aa)
CANXCalnexin. (615 aa)
DENND1ADENN domain-containing protein 1A isoform 3. (1069 aa)
FCHO2F-BAR domain only protein 2 isoform X1. (809 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (376 aa)
LOC100624109-2COesterase domain-containing protein. (836 aa)
ACTG1Actin gamma 1. (381 aa)
A0A287AA37_PIGENTH domain-containing protein. (274 aa)
NLGN3Neuroligin-3 isoform 1. (848 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (863 aa)
SYNJ1Synaptojanin 1. (1576 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
SNAP91Synaptosome associated protein 91. (906 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (973 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (955 aa)
SYNPRSynaptoporin. (288 aa)
LOC100624109COesterase domain-containing protein. (835 aa)
TBC1D24Uncharacterized protein. (559 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (142 aa)
SYT5Synaptotagmin 5. (385 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
SYT8Synaptotagmin 8. (381 aa)
AMPHUncharacterized protein. (678 aa)
SYNJ2Synaptojanin 2. (1402 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (700 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (183 aa)
SNCGGamma-synuclein; Belongs to the synuclein family. (153 aa)
SYPSynaptophysin. (319 aa)
NLGN1Neuroligin 1. (823 aa)
SYT2Synaptotagmin 2. (417 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (295 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
SYT1Synaptotagmin 1. (379 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (189 aa)
OPHN1Oligophrenin 1. (808 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (512 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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