27 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (415 aa)
	FOXQ1	Forkhead box Q1. (397 aa)
	FOXE1	Forkhead box E1. (373 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	GORAB	RAB6-interacting golgin isoform a. (369 aa)
	TMEM79	Transmembrane protein 79. (395 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	FST	Follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). (343 aa)
	KRT27	IF rod domain-containing protein; Belongs to the intermediate filament family. (460 aa)
	KRT26	Keratin 26; Belongs to the intermediate filament family. (469 aa)
	DLX3	Distal-less homeobox 3. (287 aa)
	NGFR	Nerve growth factor receptor. (414 aa)
	KRT25	Keratin 25; Belongs to the intermediate filament family. (452 aa)
	A0A5G2R3N8_PIG	Uncharacterized protein. (135 aa)
	SOSTDC1	Sclerostin domain containing 1. (229 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	PLOD3	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa)
	INTU	Inturned planar cell polarity protein. (937 aa)
	KLK14	Kallikrein related peptidase 14; Belongs to the peptidase S1 family. (252 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	NOTCH1	Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
	PLA2G10	Phospholipase A(2). (188 aa)
	TGFB2	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa)
	CTNNB1	Catenin beta 1. (808 aa)
	IGFBP5	Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (271 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	FGF10	ENSSSCP00000031836	ENSSSCP00000017886	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.527
CTNNB1	NOTCH1	ENSSSCP00000031836	ENSSSCP00000050060	Catenin beta 1.	Neurogenic locus notch homolog protein 1 preproprotein.	0.665
CTNNB1	SHH	ENSSSCP00000031836	ENSSSCP00000017394	Catenin beta 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.621
CTNNB1	SMO	ENSSSCP00000031836	ENSSSCP00000017553	Catenin beta 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.484
CTNNB1	SNAI1	ENSSSCP00000031836	ENSSSCP00000050258	Catenin beta 1.	Snail family transcriptional repressor 1.	0.568
CTNNB1	TGFB2	ENSSSCP00000031836	ENSSSCP00000035439	Catenin beta 1.	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...]	0.490
CTNNB1	WNT10A	ENSSSCP00000031836	ENSSSCP00000019894	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.553
DLX3	FGF10	ENSSSCP00000018642	ENSSSCP00000017886	Distal-less homeobox 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
DLX3	SHH	ENSSSCP00000018642	ENSSSCP00000017394	Distal-less homeobox 3.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.518
FGF10	CTNNB1	ENSSSCP00000017886	ENSSSCP00000031836	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Catenin beta 1.	0.527
FGF10	DLX3	ENSSSCP00000017886	ENSSSCP00000018642	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Distal-less homeobox 3.	0.467
FGF10	FST	ENSSSCP00000017886	ENSSSCP00000017901	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).	0.564
FGF10	NGFR	ENSSSCP00000017886	ENSSSCP00000018596	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Nerve growth factor receptor.	0.688
FGF10	SHH	ENSSSCP00000017886	ENSSSCP00000017394	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.880
FGF10	TGFB2	ENSSSCP00000017886	ENSSSCP00000035439	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...]	0.433
FOXQ1	TP63	ENSSSCP00000001059	ENSSSCP00000064786	Forkhead box Q1.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.445
FST	FGF10	ENSSSCP00000017901	ENSSSCP00000017886	Follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.564
INTU	KRT27	ENSSSCP00000056694	ENSSSCP00000018505	Inturned planar cell polarity protein.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.532
INTU	SMO	ENSSSCP00000056694	ENSSSCP00000017553	Inturned planar cell polarity protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.405
KRT25	KRT26	ENSSSCP00000018507	ENSSSCP00000018506	Keratin 25; Belongs to the intermediate filament family.	Keratin 26; Belongs to the intermediate filament family.	0.410