Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACVRL1 | BMP4 | ENSSSCP00000000247 | ENSSSCP00000005423 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 4. | 0.823 |
| ACVRL1 | BMPR1A | ENSSSCP00000000247 | ENSSSCP00000039959 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.412 |
| ACVRL1 | BMPR2 | ENSSSCP00000000247 | ENSSSCP00000070805 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.952 |
| ACVRL1 | ENG | ENSSSCP00000000247 | ENSSSCP00000030121 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] | 0.807 |
| ACVRL1 | SMAD7 | ENSSSCP00000000247 | ENSSSCP00000004862 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.608 |
| ANGPTL3 | APOB | ENSSSCP00000004131 | ENSSSCP00000042786 | Fibrinogen C-terminal domain-containing protein. | Apolipoprotein B-100. | 0.650 |
| ANGPTL3 | MYLK | ENSSSCP00000004131 | ENSSSCP00000040501 | Fibrinogen C-terminal domain-containing protein. | Myosin light chain kinase, smooth muscle; Phosphorylates a specific serine in the N-terminus of a myosin light chain. Also regulates actin-myosin interaction through a non-kinase activity (By similarity). | 0.476 |
| ANGPTL3 | SEC24B | ENSSSCP00000004131 | ENSSSCP00000009748 | Fibrinogen C-terminal domain-containing protein. | SEC24 homolog B, COPII coat complex component. | 0.562 |
| ANGPTL3 | STRA6 | ENSSSCP00000004131 | ENSSSCP00000002088 | Fibrinogen C-terminal domain-containing protein. | Stimulated by retinoic acid 6. | 0.453 |
| APOB | ANGPTL3 | ENSSSCP00000042786 | ENSSSCP00000004131 | Apolipoprotein B-100. | Fibrinogen C-terminal domain-containing protein. | 0.650 |
| APOB | APOE | ENSSSCP00000042786 | ENSSSCP00000003343 | Apolipoprotein B-100. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.988 |
| APOB | LDLR | ENSSSCP00000042786 | ENSSSCP00000070219 | Apolipoprotein B-100. | Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. | 0.696 |
| APOE | APOB | ENSSSCP00000003343 | ENSSSCP00000042786 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Apolipoprotein B-100. | 0.988 |
| APOE | EDN1 | ENSSSCP00000003343 | ENSSSCP00000043269 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.542 |
| APOE | LDLR | ENSSSCP00000003343 | ENSSSCP00000070219 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. | 0.715 |
| APOE | LRP2 | ENSSSCP00000003343 | ENSSSCP00000049411 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] | 0.547 |
| ARID2 | NF1 | ENSSSCP00000039026 | ENSSSCP00000018804 | AT-rich interaction domain 2. | Neurofibromin 1. | 0.441 |
| BMP4 | ACVRL1 | ENSSSCP00000005423 | ENSSSCP00000000247 | Bone morphogenetic protein 4. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.823 |
| BMP4 | BMPR1A | ENSSSCP00000005423 | ENSSSCP00000039959 | Bone morphogenetic protein 4. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.995 |
| BMP4 | BMPR2 | ENSSSCP00000005423 | ENSSSCP00000070805 | Bone morphogenetic protein 4. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.985 |
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