(21 nodes) Arachidonic acid secretion network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A5G2R3N8_PIG	Uncharacterized protein. (135 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	PLA2G2E	Phospholipase A(2). (142 aa)
	PLA2G10	Phospholipase A(2). (188 aa)
	PLA2G2D	Phospholipase A(2). (161 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	PROCA1	Protein interacting with cyclin A1. (392 aa)
	PLA2G2C	PA2c domain-containing protein. (174 aa)
	PLA2G4F	Phospholipase A2. (852 aa)
	ANXA1	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa)
	OC90	Uncharacterized protein. (472 aa)
	PLA2G3	Phospholipase A2 group III. (501 aa)
	PLA2G12B	Phospholipase A2 group XIIB. (194 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
	PNPLA8	Calcium-independent phospholipase A2-gamma isoform 1. (783 aa)
	NMUR2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (410 aa)
	BDKRB2	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (440 aa)
	PLA2G2A	Phospholipase A(2). (125 aa)
	PLA2G2F	Phospholipase A(2). (302 aa)
	PLA2G1B	Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family. (146 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	NMUR2	ENSSSCP00000005658	ENSSSCP00000018092	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.499
DRD3	DRD4	ENSSSCP00000012691	ENSSSCP00000013661	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.851
DRD4	DRD3	ENSSSCP00000013661	ENSSSCP00000012691	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.851
NMUR2	ANXA1	ENSSSCP00000018092	ENSSSCP00000005658	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	0.499
PLA2G10	PLA2G12B	ENSSSCP00000048031	ENSSSCP00000010971	Phospholipase A(2).	Phospholipase A2 group XIIB.	0.614
PLA2G10	PLA2G1B	ENSSSCP00000048031	ENSSSCP00000072242	Phospholipase A(2).	Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family.	0.607
PLA2G10	PLA2G2A	ENSSSCP00000048031	ENSSSCP00000031428	Phospholipase A(2).	Phospholipase A(2).	0.584
PLA2G10	PLA2G2D	ENSSSCP00000048031	ENSSSCP00000038538	Phospholipase A(2).	Phospholipase A(2).	0.569
PLA2G10	PLA2G2E	ENSSSCP00000048031	ENSSSCP00000048306	Phospholipase A(2).	Phospholipase A(2).	0.555
PLA2G10	PLA2G2F	ENSSSCP00000048031	ENSSSCP00000032667	Phospholipase A(2).	Phospholipase A(2).	0.592
PLA2G10	PLA2G3	ENSSSCP00000048031	ENSSSCP00000010694	Phospholipase A(2).	Phospholipase A2 group III.	0.848
PLA2G10	PLA2G4F	ENSSSCP00000048031	ENSSSCP00000005102	Phospholipase A(2).	Phospholipase A2.	0.510
PLA2G10	PLA2G5	ENSSSCP00000048031	ENSSSCP00000036267	Phospholipase A(2).	Phospholipase A(2).	0.591
PLA2G12B	PLA2G10	ENSSSCP00000010971	ENSSSCP00000048031	Phospholipase A2 group XIIB.	Phospholipase A(2).	0.614
PLA2G12B	PLA2G1B	ENSSSCP00000010971	ENSSSCP00000072242	Phospholipase A2 group XIIB.	Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family.	0.701
PLA2G12B	PLA2G2A	ENSSSCP00000010971	ENSSSCP00000031428	Phospholipase A2 group XIIB.	Phospholipase A(2).	0.551
PLA2G12B	PLA2G2C	ENSSSCP00000010971	ENSSSCP00000003799	Phospholipase A2 group XIIB.	PA2c domain-containing protein.	0.684
PLA2G12B	PLA2G2D	ENSSSCP00000010971	ENSSSCP00000038538	Phospholipase A2 group XIIB.	Phospholipase A(2).	0.523
PLA2G12B	PLA2G2E	ENSSSCP00000010971	ENSSSCP00000048306	Phospholipase A2 group XIIB.	Phospholipase A(2).	0.642
PLA2G12B	PLA2G2F	ENSSSCP00000010971	ENSSSCP00000032667	Phospholipase A2 group XIIB.	Phospholipase A(2).	0.762