Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARG2 | CD80 | ENSSSCP00000002491 | ENSSSCP00000012679 | Arginase. | CD80 molecule. | 0.488 |
| ARG2 | CD86 | ENSSSCP00000002491 | ENSSSCP00000028828 | Arginase. | T-lymphocyte activation antigen CD86 isoform 1. | 0.442 |
| ARG2 | IDO1 | ENSSSCP00000002491 | ENSSSCP00000007468 | Arginase. | Uncharacterized protein. | 0.458 |
| ARG2 | IL10 | ENSSSCP00000002491 | ENSSSCP00000016594 | Arginase. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.804 |
| BMP4 | IHH | ENSSSCP00000005423 | ENSSSCP00000017167 | Bone morphogenetic protein 4. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.721 |
| BMP4 | SHH | ENSSSCP00000005423 | ENSSSCP00000017394 | Bone morphogenetic protein 4. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.850 |
| BMP4 | TWSG1 | ENSSSCP00000005423 | ENSSSCP00000068029 | Bone morphogenetic protein 4. | Twisted gastrulation BMP signaling modulator 1. | 0.476 |
| BTK | LYN | ENSSSCP00000025530 | ENSSSCP00000006663 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.952 |
| BTK | PTPN6 | ENSSSCP00000025530 | ENSSSCP00000036336 | Tyrosine-protein kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.928 |
| BTK | TYROBP | ENSSSCP00000025530 | ENSSSCP00000003143 | Tyrosine-protein kinase. | TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...] | 0.665 |
| CBLB | ERBB2 | ENSSSCP00000048070 | ENSSSCP00000018545 | E3 ubiquitin-protein ligase CBL-B isoform X1. | Receptor protein-tyrosine kinase. | 0.639 |
| CBLB | LYN | ENSSSCP00000048070 | ENSSSCP00000006663 | E3 ubiquitin-protein ligase CBL-B isoform X1. | Tyrosine-protein kinase. | 0.613 |
| CD274 | CD80 | ENSSSCP00000005602 | ENSSSCP00000012679 | CD274 molecule. | CD80 molecule. | 0.993 |
| CD274 | CD86 | ENSSSCP00000005602 | ENSSSCP00000028828 | CD274 molecule. | T-lymphocyte activation antigen CD86 isoform 1. | 0.590 |
| CD274 | CTLA4 | ENSSSCP00000005602 | ENSSSCP00000031088 | CD274 molecule. | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | 0.603 |
| CD274 | FOXP3 | ENSSSCP00000005602 | ENSSSCP00000049858 | CD274 molecule. | Forkhead box protein P3 isoform a. | 0.489 |
| CD274 | HAVCR2 | ENSSSCP00000005602 | ENSSSCP00000026109 | CD274 molecule. | Hepatitis A virus cellular receptor 2. | 0.670 |
| CD274 | IDO1 | ENSSSCP00000005602 | ENSSSCP00000007468 | CD274 molecule. | Uncharacterized protein. | 0.607 |
| CD274 | IL10 | ENSSSCP00000005602 | ENSSSCP00000016594 | CD274 molecule. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.501 |
| CD274 | IL2 | ENSSSCP00000005602 | ENSSSCP00000059176 | CD274 molecule. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.431 |
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